OLA1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	18 studies	22% ± 7%	Explore
endothelial cell	18 studies	31% ± 11%	Explore
CD4-positive, alpha-beta T cell	16 studies	26% ± 10%	Explore
pericyte	16 studies	21% ± 6%	Explore
B cell	15 studies	21% ± 6%	Explore
CD8-positive, alpha-beta T cell	15 studies	25% ± 8%	Explore
epithelial cell	14 studies	36% ± 20%	Explore
fibroblast	14 studies	23% ± 9%	Explore
smooth muscle cell	14 studies	21% ± 5%	Explore
regulatory T cell	14 studies	21% ± 6%	Explore
conventional dendritic cell	13 studies	28% ± 17%	Explore
T cell	12 studies	22% ± 8%	Explore
basal cell	12 studies	31% ± 17%	Explore
dendritic cell	12 studies	33% ± 22%	Explore
astrocyte	12 studies	32% ± 15%	Explore
GABAergic neuron	11 studies	42% ± 23%	Explore
glutamatergic neuron	11 studies	47% ± 25%	Explore
macrophage	11 studies	27% ± 9%	Explore
oligodendrocyte precursor cell	11 studies	36% ± 15%	Explore
oligodendrocyte	11 studies	31% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	22% ± 4%	Explore
myofibroblast cell	10 studies	21% ± 5%	Explore
endothelial cell of lymphatic vessel	10 studies	24% ± 7%	Explore
neuron	9 studies	44% ± 19%	Explore
naive B cell	9 studies	19% ± 5%	Explore
microglial cell	9 studies	27% ± 9%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	20% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	21% ± 4%	Explore
mesothelial cell	8 studies	28% ± 12%	Explore
mucosal invariant T cell	8 studies	19% ± 3%	Explore
adipocyte	8 studies	24% ± 7%	Explore
memory B cell	8 studies	20% ± 5%	Explore
plasmacytoid dendritic cell	8 studies	25% ± 8%	Explore
gamma-delta T cell	8 studies	25% ± 18%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	21% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	23% ± 5%	Explore
progenitor cell	7 studies	28% ± 8%	Explore
monocyte	7 studies	19% ± 4%	Explore
retinal ganglion cell	7 studies	43% ± 24%	Explore
club cell	7 studies	23% ± 8%	Explore
type I pneumocyte	7 studies	27% ± 7%	Explore
type II pneumocyte	7 studies	25% ± 7%	Explore
abnormal cell	7 studies	31% ± 16%	Explore
mature NK T cell	6 studies	19% ± 5%	Explore
connective tissue cell	6 studies	24% ± 7%	Explore
interneuron	6 studies	52% ± 23%	Explore
hematopoietic stem cell	6 studies	41% ± 14%	Explore
retina horizontal cell	6 studies	31% ± 9%	Explore
retinal cone cell	6 studies	33% ± 10%	Explore
retinal rod cell	6 studies	26% ± 7%	Explore
mast cell	5 studies	23% ± 7%	Explore
hematopoietic precursor cell	5 studies	44% ± 15%	Explore
classical monocyte	5 studies	27% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	21% ± 3%	Explore
enteroendocrine cell	5 studies	26% ± 12%	Explore
erythroblast	5 studies	33% ± 15%	Explore
lymphocyte	5 studies	24% ± 7%	Explore
precursor B cell	5 studies	28% ± 10%	Explore
pro-B cell	5 studies	29% ± 1%	Explore
myeloid cell	5 studies	28% ± 6%	Explore
amacrine cell	5 studies	33% ± 7%	Explore
cardiac muscle cell	5 studies	18% ± 2%	Explore
ciliated cell	5 studies	31% ± 9%	Explore
goblet cell	5 studies	31% ± 18%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	22% ± 8%	Explore
non-classical monocyte	4 studies	28% ± 9%	Explore
kidney loop of Henle epithelial cell	4 studies	17% ± 1%	Explore
epithelial cell of proximal tubule	4 studies	22% ± 5%	Explore
intestinal crypt stem cell	4 studies	28% ± 2%	Explore
leukocyte	4 studies	20% ± 5%	Explore
granule cell	4 studies	32% ± 8%	Explore
immature B cell	4 studies	22% ± 6%	Explore
retinal bipolar neuron	4 studies	29% ± 5%	Explore
Mueller cell	4 studies	27% ± 12%	Explore
OFF-bipolar cell	4 studies	35% ± 14%	Explore
ON-bipolar cell	4 studies	36% ± 16%	Explore
T follicular helper cell	4 studies	18% ± 1%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	29% ± 5%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	25% ± 8%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	29% ± 6%	Explore
hepatocyte	4 studies	42% ± 22%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	25% ± 7%	Explore
transit amplifying cell	4 studies	36% ± 26%	Explore
plasmablast	3 studies	57% ± 6%	Explore
pancreatic A cell	3 studies	35% ± 12%	Explore
type B pancreatic cell	3 studies	42% ± 20%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	31% ± 10%	Explore
enterocyte	3 studies	19% ± 3%	Explore
neural crest cell	3 studies	35% ± 4%	Explore
GABAergic interneuron	3 studies	36% ± 3%	Explore
glial cell	3 studies	32% ± 17%	Explore
placental villous trophoblast	3 studies	28% ± 4%	Explore
common myeloid progenitor	3 studies	37% ± 26%	Explore
plasma cell	3 studies	35% ± 14%	Explore
brush cell	3 studies	27% ± 13%	Explore
retinal pigment epithelial cell	3 studies	30% ± 13%	Explore
GABAergic amacrine cell	3 studies	34% ± 3%	Explore
glycinergic amacrine cell	3 studies	28% ± 2%	Explore
rod bipolar cell	3 studies	31% ± 7%	Explore
germinal center B cell	3 studies	22% ± 3%	Explore
exhausted T cell	3 studies	18% ± 4%	Explore
endothelial cell of vascular tree	3 studies	24% ± 11%	Explore
pancreatic ductal cell	3 studies	48% ± 17%	Explore
ependymal cell	3 studies	31% ± 13%	Explore
granulocyte monocyte progenitor cell	3 studies	31% ± 6%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	58% ± 19%	Explore
respiratory goblet cell	3 studies	30% ± 6%	Explore
alveolar macrophage	3 studies	26% ± 7%	Explore
group 3 innate lymphoid cell	3 studies	27% ± 12%	Explore
innate lymphoid cell	3 studies	19% ± 3%	Explore
double negative thymocyte	3 studies	36% ± 20%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	16 studies	36% ± 21%	Explore
peripheral blood	13 studies	22% ± 7%	Explore
lung	10 studies	26% ± 9%	Explore
eye	8 studies	29% ± 9%	Explore
intestine	6 studies	21% ± 8%	Explore
kidney	5 studies	19% ± 2%	Explore
bone marrow	4 studies	20% ± 4%	Explore
liver	4 studies	39% ± 22%	Explore
adipose	4 studies	23% ± 11%	Explore
pancreas	3 studies	40% ± 14%	Explore
lymph node	3 studies	25% ± 4%	Explore
breast	3 studies	17% ± 1%	Explore
placenta	3 studies	20% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2797.41	1445 / 1445	100%	62.59	183 / 183
ovary	100%	1981.01	180 / 180	100%	69.14	430 / 430
prostate	100%	2383.57	245 / 245	100%	51.52	502 / 502
breast	100%	2603.74	459 / 459	100%	68.82	1117 / 1118
intestine	100%	2548.77	966 / 966	100%	65.92	526 / 527
bladder	100%	2665.10	21 / 21	100%	52.00	503 / 504
uterus	100%	2092.43	170 / 170	100%	56.04	458 / 459
brain	100%	4347.61	2634 / 2642	100%	48.16	705 / 705
pancreas	100%	2348.77	327 / 328	100%	37.83	178 / 178
stomach	100%	2161.84	359 / 359	100%	60.64	285 / 286
thymus	100%	2336.15	652 / 653	100%	48.37	603 / 605
lung	99%	2001.81	573 / 578	100%	56.25	1155 / 1155
skin	100%	3906.54	1808 / 1809	99%	46.08	466 / 472
kidney	100%	2489.48	89 / 89	97%	38.87	877 / 901
adrenal gland	100%	2840.81	258 / 258	97%	35.09	222 / 230
liver	91%	1255.32	205 / 226	98%	27.83	396 / 406
adipose	100%	2534.35	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	43.68	29 / 29
muscle	100%	4491.25	803 / 803	0%	0	0 / 0
spleen	100%	1473.95	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	47.51	45 / 45
ureter	0%	0	0 / 0	100%	13.57	1 / 1
blood vessel	100%	2781.47	1334 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	96%	31.80	77 / 80
heart	93%	2145.13	801 / 861	0%	0	0 / 0
peripheral blood	79%	2560.46	733 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0046034	Biological process	ATP metabolic process
GO_0005813	Cellular component	centrosome
GO_0005730	Cellular component	nucleolus
GO_0070062	Cellular component	extracellular exosome
GO_0005829	Cellular component	cytosol
GO_0005576	Cellular component	extracellular region
GO_0031093	Cellular component	platelet alpha granule lumen
GO_0016020	Cellular component	membrane
GO_0005737	Cellular component	cytoplasm
GO_0043023	Molecular function	ribosomal large subunit binding
GO_0045296	Molecular function	cadherin binding
GO_0005525	Molecular function	GTP binding
GO_0005515	Molecular function	protein binding
GO_0016887	Molecular function	ATP hydrolysis activity
GO_0046872	Molecular function	metal ion binding
GO_0005524	Molecular function	ATP binding

IV. Literature review

[source]

Gene name	OLA1
Protein name	Obg-like ATPase 1 Obg like ATPase 1 Obg-like ATPase 1 (DNA damage-regulated overexpressed in cancer 45) (DOC45) (GTP-binding protein 9)
Synonyms	PTD004 PRO2455 GTPBP9
Description	FUNCTION: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. . FUNCTION: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. .
Accessions	ENST00000409546.5 ENST00000344357.9 [Q9NTK5-2] J3KQ32 C9JCJ9 Q9NTK5 ENST00000429575.1 C9JTK6 ENST00000428402.6 [Q9NTK5-3] ENST00000427472.2 ENST00000284719.8 [Q9NTK5-1]

OLA1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review