Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| lung | 14 studies | 36% ± 14% | |
| peripheral blood | 14 studies | 27% ± 8% | |
| intestine | 10 studies | 29% ± 14% | |
| kidney | 9 studies | 33% ± 7% | |
| brain | 8 studies | 23% ± 6% | |
| eye | 7 studies | 32% ± 16% | |
| liver | 6 studies | 31% ± 23% | |
| lymph node | 5 studies | 29% ± 11% | |
| pancreas | 4 studies | 46% ± 19% | |
| bone marrow | 4 studies | 22% ± 3% | |
| uterus | 4 studies | 30% ± 17% | |
| adrenal gland | 3 studies | 25% ± 4% | |
| thymus | 3 studies | 50% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 1778.28 | 2642 / 2642 | 100% | 147.55 | 705 / 705 |
| esophagus | 100% | 1556.59 | 1445 / 1445 | 100% | 128.77 | 183 / 183 |
| ovary | 100% | 725.14 | 180 / 180 | 100% | 173.54 | 430 / 430 |
| stomach | 100% | 1254.90 | 359 / 359 | 100% | 145.44 | 286 / 286 |
| intestine | 100% | 1655.03 | 966 / 966 | 100% | 151.12 | 526 / 527 |
| bladder | 100% | 1221.86 | 21 / 21 | 100% | 135.54 | 503 / 504 |
| kidney | 100% | 2612.85 | 89 / 89 | 100% | 126.08 | 899 / 901 |
| prostate | 100% | 1174.14 | 245 / 245 | 100% | 129.25 | 500 / 502 |
| adrenal gland | 100% | 2020.19 | 258 / 258 | 100% | 141.67 | 229 / 230 |
| liver | 100% | 1156.93 | 225 / 226 | 100% | 125.69 | 406 / 406 |
| breast | 100% | 1128.87 | 458 / 459 | 100% | 146.22 | 1114 / 1118 |
| thymus | 100% | 1351.21 | 650 / 653 | 100% | 132.62 | 604 / 605 |
| skin | 99% | 1314.01 | 1789 / 1809 | 100% | 132.14 | 472 / 472 |
| uterus | 99% | 841.65 | 168 / 170 | 100% | 161.09 | 459 / 459 |
| lung | 98% | 1091.16 | 569 / 578 | 100% | 138.35 | 1155 / 1155 |
| pancreas | 91% | 566.20 | 300 / 328 | 100% | 130.57 | 178 / 178 |
| eye | 0% | 0 | 0 / 0 | 100% | 100.10 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 199.87 | 29 / 29 |
| muscle | 100% | 3882.99 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1392.51 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 153.78 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 73.53 | 1 / 1 |
| adipose | 100% | 1162.56 | 1200 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 1114.33 | 1326 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 4535.97 | 848 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 69% | 1248.59 | 638 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0009060 | Biological process | aerobic respiration |
| GO_0006120 | Biological process | mitochondrial electron transport, NADH to ubiquinone |
| GO_0042776 | Biological process | proton motive force-driven mitochondrial ATP synthesis |
| GO_0055085 | Biological process | transmembrane transport |
| GO_0032981 | Biological process | mitochondrial respiratory chain complex I assembly |
| GO_0045271 | Cellular component | respiratory chain complex I |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0008137 | Molecular function | NADH dehydrogenase (ubiquinone) activity |
| Gene name | NDUFB3 |
| Protein name | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (Complex I-B12) (NADH-ubiquinone oxidoreductase B12 subunit) NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (Complex I-B12) (CI-B12) (NADH-ubiquinone oxidoreductase B12 subunit) |
| Synonyms | |
| Description | FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . |
| Accessions | ENST00000450023.6 O43676 ENST00000684175.1 ENST00000682325.1 ENST00000684420.1 C9JKQ2 ENST00000454214.1 ENST00000450023 ENST00000433898.5 ENST00000237889.9 |