NASP | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	39 studies	34% ± 13%	Explore
B cell	30 studies	27% ± 8%	Explore
fibroblast	29 studies	29% ± 12%	Explore
natural killer cell	27 studies	31% ± 16%	Explore
T cell	21 studies	31% ± 12%	Explore
CD4-positive, alpha-beta T cell	21 studies	29% ± 16%	Explore
CD8-positive, alpha-beta T cell	21 studies	32% ± 15%	Explore
macrophage	19 studies	24% ± 7%	Explore
pericyte	19 studies	30% ± 11%	Explore
regulatory T cell	18 studies	26% ± 12%	Explore
endothelial cell of lymphatic vessel	17 studies	28% ± 11%	Explore
smooth muscle cell	17 studies	29% ± 10%	Explore
memory B cell	15 studies	25% ± 12%	Explore
conventional dendritic cell	14 studies	27% ± 12%	Explore
naive B cell	13 studies	26% ± 9%	Explore
oligodendrocyte	13 studies	34% ± 12%	Explore
endothelial cell of vascular tree	13 studies	34% ± 11%	Explore
gamma-delta T cell	13 studies	30% ± 18%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	24% ± 7%	Explore
epithelial cell	12 studies	38% ± 20%	Explore
oligodendrocyte precursor cell	12 studies	32% ± 13%	Explore
plasmacytoid dendritic cell	12 studies	27% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	23% ± 5%	Explore
connective tissue cell	11 studies	38% ± 16%	Explore
vein endothelial cell	11 studies	30% ± 12%	Explore
astrocyte	11 studies	32% ± 14%	Explore
basal cell	11 studies	30% ± 9%	Explore
ciliated cell	11 studies	28% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	10 studies	23% ± 9%	Explore
capillary endothelial cell	10 studies	27% ± 13%	Explore
endothelial cell of artery	10 studies	29% ± 10%	Explore
mature NK T cell	9 studies	22% ± 7%	Explore
myofibroblast cell	9 studies	36% ± 11%	Explore
mucosal invariant T cell	9 studies	22% ± 7%	Explore
mast cell	8 studies	24% ± 11%	Explore
plasmablast	8 studies	47% ± 21%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	38% ± 17%	Explore
mesothelial cell	8 studies	33% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	30% ± 13%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	24% ± 8%	Explore
GABAergic neuron	7 studies	29% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	26% ± 11%	Explore
progenitor cell	7 studies	46% ± 11%	Explore
monocyte	7 studies	23% ± 7%	Explore
abnormal cell	7 studies	36% ± 15%	Explore
neuron	7 studies	38% ± 12%	Explore
precursor B cell	7 studies	40% ± 10%	Explore
myeloid cell	7 studies	26% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	33% ± 10%	Explore
hematopoietic precursor cell	6 studies	44% ± 22%	Explore
classical monocyte	6 studies	23% ± 8%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	26% ± 9%	Explore
leukocyte	6 studies	33% ± 11%	Explore
transit amplifying cell	6 studies	29% ± 13%	Explore
microglial cell	6 studies	25% ± 6%	Explore
hematopoietic stem cell	6 studies	41% ± 19%	Explore
dendritic cell	6 studies	31% ± 20%	Explore
T follicular helper cell	6 studies	21% ± 5%	Explore
innate lymphoid cell	6 studies	26% ± 9%	Explore
non-classical monocyte	5 studies	30% ± 9%	Explore
interneuron	5 studies	33% ± 17%	Explore
pro-B cell	5 studies	51% ± 10%	Explore
plasma cell	5 studies	36% ± 21%	Explore
immature B cell	5 studies	38% ± 14%	Explore
retinal rod cell	5 studies	19% ± 1%	Explore
secretory cell	5 studies	28% ± 9%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	31% ± 10%	Explore
type I pneumocyte	4 studies	24% ± 5%	Explore
exhausted T cell	4 studies	29% ± 8%	Explore
enteroendocrine cell	4 studies	28% ± 7%	Explore
intestinal crypt stem cell	4 studies	23% ± 6%	Explore
erythroblast	4 studies	50% ± 15%	Explore
lymphocyte	4 studies	40% ± 14%	Explore
glutamatergic neuron	4 studies	41% ± 9%	Explore
neural crest cell	3 studies	65% ± 7%	Explore
glial cell	3 studies	38% ± 19%	Explore
extravillous trophoblast	3 studies	26% ± 5%	Explore
placental villous trophoblast	3 studies	61% ± 11%	Explore
brush cell	3 studies	30% ± 11%	Explore
club cell	3 studies	22% ± 8%	Explore
type II pneumocyte	3 studies	23% ± 5%	Explore
retinal cone cell	3 studies	28% ± 5%	Explore
Mueller cell	3 studies	19% ± 3%	Explore
germinal center B cell	3 studies	28% ± 13%	Explore
myoepithelial cell	3 studies	35% ± 9%	Explore
granulocyte monocyte progenitor cell	3 studies	53% ± 27%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	65% ± 10%	Explore
goblet cell	3 studies	23% ± 6%	Explore
erythrocyte	3 studies	49% ± 24%	Explore
group 3 innate lymphoid cell	3 studies	38% ± 17%	Explore
hepatocyte	3 studies	33% ± 12%	Explore
double negative thymocyte	3 studies	37% ± 25%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	29% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	14 studies	28% ± 13%	Explore
lung	11 studies	26% ± 6%	Explore
peripheral blood	9 studies	27% ± 11%	Explore
intestine	8 studies	28% ± 13%	Explore
liver	6 studies	31% ± 18%	Explore
kidney	5 studies	24% ± 10%	Explore
eye	5 studies	24% ± 9%	Explore
uterus	5 studies	32% ± 16%	Explore
lymph node	5 studies	29% ± 15%	Explore
breast	4 studies	28% ± 9%	Explore
adipose	4 studies	19% ± 2%	Explore
placenta	3 studies	39% ± 9%	Explore
bone marrow	3 studies	26% ± 8%	Explore
ovary	3 studies	26% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	5829.00	21 / 21	100%	56.61	504 / 504
esophagus	100%	5486.31	1445 / 1445	100%	39.40	183 / 183
uterus	100%	8588.35	170 / 170	100%	96.22	459 / 459
brain	100%	4994.95	2639 / 2642	100%	55.51	705 / 705
thymus	100%	6274.13	653 / 653	100%	39.55	604 / 605
lung	100%	6284.63	578 / 578	100%	45.20	1152 / 1155
prostate	100%	6885.35	245 / 245	100%	27.90	500 / 502
breast	100%	7103.89	459 / 459	100%	46.46	1113 / 1118
ovary	100%	9115.63	180 / 180	99%	36.05	427 / 430
intestine	100%	6037.63	966 / 966	99%	41.00	523 / 527
skin	100%	5405.44	1809 / 1809	99%	43.38	466 / 472
stomach	100%	4159.91	359 / 359	99%	35.57	282 / 286
pancreas	98%	2271.44	320 / 328	98%	34.59	175 / 178
kidney	100%	4169.07	89 / 89	94%	25.54	849 / 901
adrenal gland	100%	3701.66	258 / 258	93%	19.81	215 / 230
liver	100%	2907.94	226 / 226	92%	23.64	375 / 406
adipose	100%	7027.95	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	86.32	29 / 29
spleen	100%	9140.95	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	79.53	45 / 45
ureter	0%	0	0 / 0	100%	38.88	1 / 1
blood vessel	100%	4908.36	1334 / 1335	0%	0	0 / 0
muscle	99%	2896.56	796 / 803	0%	0	0 / 0
heart	99%	3852.83	849 / 861	0%	0	0 / 0
peripheral blood	87%	4349.30	807 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	59%	11.68	47 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0008584	Biological process	male gonad development
GO_0033574	Biological process	response to testosterone
GO_0015031	Biological process	protein transport
GO_0006335	Biological process	DNA replication-dependent chromatin assembly
GO_0001824	Biological process	blastocyst development
GO_0034080	Biological process	CENP-A containing chromatin assembly
GO_0006260	Biological process	DNA replication
GO_0006334	Biological process	nucleosome assembly
GO_0032991	Cellular component	protein-containing complex
GO_0005654	Cellular component	nucleoplasm
GO_0000785	Cellular component	chromatin
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0042393	Molecular function	histone binding

IV. Literature review

[source]

Gene name	NASP
Protein name	Nuclear autoantigenic sperm protein (NASP) NASP protein Nuclear autoantigenic sperm protein
Synonyms	hCG_40880
Description	FUNCTION: Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA. .
Accessions	ENST00000531612.5 ENST00000528084.5 E9PAU3 Q5T626 E9PPQ8 ENST00000437901.6 ENST00000470768.5 E9PJQ2 H0YDS9 Q6PJY7 ENST00000534450.1 ENST00000529333.5 E9PRH9 P49321 E9PI86 ENST00000525515.5 ENST00000527359.5 Q9P1N1 ENST00000528238.5 ENST00000530840.5 E9PPR5 ENST00000437362.6 E9PKR5 ENST00000531532.5 E9PNB5 ENST00000527470.5 Q5T624 E9PQG5 H0YF33 ENST00000453748.5 ENST00000372052.8 ENST00000350030.8 [P49321-1] ENST00000537798.5 [P49321-4] ENST00000629893.1 ENST00000351223.7 [P49321-2]

NASP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review