MAPRE1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	27 studies	23% ± 5%	Explore
CD8-positive, alpha-beta T cell	19 studies	20% ± 5%	Explore
macrophage	18 studies	22% ± 9%	Explore
mast cell	18 studies	29% ± 8%	Explore
CD4-positive, alpha-beta T cell	16 studies	22% ± 7%	Explore
endothelial cell	16 studies	25% ± 8%	Explore
smooth muscle cell	15 studies	24% ± 5%	Explore
T cell	14 studies	21% ± 4%	Explore
regulatory T cell	14 studies	19% ± 4%	Explore
classical monocyte	13 studies	24% ± 11%	Explore
non-classical monocyte	13 studies	25% ± 12%	Explore
pericyte	13 studies	21% ± 4%	Explore
B cell	11 studies	22% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	22% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	26% ± 5%	Explore
mature NK T cell	10 studies	19% ± 3%	Explore
plasmacytoid dendritic cell	10 studies	24% ± 8%	Explore
fibroblast	10 studies	26% ± 7%	Explore
gamma-delta T cell	10 studies	26% ± 13%	Explore
monocyte	9 studies	23% ± 7%	Explore
conventional dendritic cell	9 studies	31% ± 14%	Explore
memory B cell	9 studies	19% ± 3%	Explore
mucosal invariant T cell	9 studies	22% ± 6%	Explore
naive B cell	8 studies	21% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	21% ± 5%	Explore
myeloid cell	8 studies	28% ± 10%	Explore
endothelial cell of vascular tree	8 studies	21% ± 5%	Explore
basal cell	8 studies	26% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	19% ± 3%	Explore
precursor B cell	7 studies	36% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	25% ± 6%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	19% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	23% ± 6%	Explore
myofibroblast cell	6 studies	23% ± 5%	Explore
connective tissue cell	6 studies	22% ± 3%	Explore
innate lymphoid cell	6 studies	21% ± 4%	Explore
epithelial cell	6 studies	36% ± 18%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	23% ± 6%	Explore
mononuclear phagocyte	5 studies	23% ± 10%	Explore
hematopoietic precursor cell	5 studies	30% ± 9%	Explore
endothelial cell of artery	5 studies	19% ± 4%	Explore
pro-B cell	5 studies	28% ± 8%	Explore
platelet	5 studies	20% ± 6%	Explore
plasmablast	4 studies	44% ± 16%	Explore
pancreatic A cell	4 studies	57% ± 16%	Explore
leukocyte	4 studies	25% ± 6%	Explore
exhausted T cell	4 studies	21% ± 4%	Explore
vein endothelial cell	4 studies	18% ± 3%	Explore
capillary endothelial cell	4 studies	21% ± 3%	Explore
ciliated cell	4 studies	30% ± 8%	Explore
abnormal cell	4 studies	21% ± 6%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	23% ± 7%	Explore
dendritic cell	4 studies	38% ± 21%	Explore
T follicular helper cell	4 studies	18% ± 2%	Explore
neuron	4 studies	27% ± 17%	Explore
type B pancreatic cell	3 studies	59% ± 19%	Explore
neural crest cell	3 studies	19% ± 1%	Explore
lymphocyte	3 studies	23% ± 8%	Explore
plasma cell	3 studies	27% ± 13%	Explore
immature B cell	3 studies	31% ± 9%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	18% ± 2%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	24% ± 5%	Explore
granulocyte	3 studies	35% ± 8%	Explore
endothelial cell of lymphatic vessel	3 studies	25% ± 7%	Explore
glutamatergic neuron	3 studies	26% ± 2%	Explore
pancreatic ductal cell	3 studies	49% ± 19%	Explore
hematopoietic stem cell	3 studies	22% ± 4%	Explore
megakaryocyte	3 studies	31% ± 3%	Explore
enteroendocrine cell	3 studies	23% ± 11%	Explore
goblet cell	3 studies	18% ± 3%	Explore
group 3 innate lymphoid cell	3 studies	36% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	17% ± 3%	Explore
double negative thymocyte	3 studies	32% ± 14%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	13 studies	22% ± 9%	Explore
lung	8 studies	25% ± 7%	Explore
kidney	4 studies	17% ± 2%	Explore
bone marrow	4 studies	22% ± 5%	Explore
uterus	4 studies	22% ± 7%	Explore
lymph node	4 studies	17% ± 1%	Explore
brain	4 studies	20% ± 4%	Explore
pancreas	3 studies	58% ± 9%	Explore
intestine	3 studies	22% ± 9%	Explore
liver	3 studies	29% ± 16%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	6329.08	1445 / 1445	100%	186.15	183 / 183
lung	100%	6206.36	578 / 578	100%	207.24	1155 / 1155
ovary	100%	4481.83	180 / 180	100%	159.75	430 / 430
stomach	100%	4472.51	359 / 359	100%	221.33	286 / 286
uterus	100%	6291.63	170 / 170	100%	229.47	459 / 459
skin	100%	5078.41	1808 / 1809	100%	237.04	472 / 472
breast	100%	5748.27	459 / 459	100%	237.47	1117 / 1118
intestine	100%	6891.11	966 / 966	100%	225.91	526 / 527
bladder	100%	6807.29	21 / 21	100%	218.57	503 / 504
thymus	100%	5469.01	653 / 653	100%	186.04	603 / 605
prostate	100%	4929.34	244 / 245	100%	145.25	501 / 502
kidney	100%	4583.97	89 / 89	99%	150.08	894 / 901
adrenal gland	100%	4202.70	258 / 258	98%	139.27	225 / 230
brain	98%	3432.57	2578 / 2642	100%	274.18	705 / 705
pancreas	97%	2359.41	318 / 328	99%	167.93	176 / 178
liver	47%	785.09	107 / 226	72%	57.49	292 / 406
adipose	100%	6230.70	1204 / 1204	0%	0	0 / 0
blood vessel	100%	7395.15	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	151.62	80 / 80
lymph node	0%	0	0 / 0	100%	221.45	29 / 29
spleen	100%	5042.22	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	237.43	45 / 45
ureter	0%	0	0 / 0	100%	92.65	1 / 1
muscle	99%	2419.04	797 / 803	0%	0	0 / 0
peripheral blood	99%	6665.30	922 / 929	0%	0	0 / 0
heart	97%	3716.64	831 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0