IMP3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	25 studies	25% ± 6%	Explore
CD8-positive, alpha-beta T cell	24 studies	27% ± 7%	Explore
CD4-positive, alpha-beta T cell	22 studies	26% ± 6%	Explore
regulatory T cell	17 studies	28% ± 6%	Explore
memory B cell	16 studies	23% ± 6%	Explore
B cell	16 studies	25% ± 6%	Explore
T cell	14 studies	22% ± 7%	Explore
naive B cell	14 studies	24% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	28% ± 8%	Explore
gamma-delta T cell	13 studies	29% ± 11%	Explore
endothelial cell	13 studies	29% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	26% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	29% ± 4%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	27% ± 6%	Explore
basal cell	11 studies	30% ± 14%	Explore
mature NK T cell	11 studies	26% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	25% ± 5%	Explore
fibroblast	10 studies	26% ± 13%	Explore
mucosal invariant T cell	9 studies	28% ± 5%	Explore
plasmacytoid dendritic cell	9 studies	25% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	29% ± 5%	Explore
conventional dendritic cell	8 studies	26% ± 12%	Explore
non-classical monocyte	8 studies	23% ± 8%	Explore
macrophage	8 studies	22% ± 8%	Explore
epithelial cell	8 studies	41% ± 19%	Explore
endothelial cell of lymphatic vessel	7 studies	23% ± 8%	Explore
plasma cell	7 studies	28% ± 10%	Explore
capillary endothelial cell	7 studies	20% ± 5%	Explore
endothelial cell of artery	7 studies	19% ± 4%	Explore
abnormal cell	7 studies	26% ± 10%	Explore
ciliated cell	7 studies	33% ± 13%	Explore
mast cell	6 studies	21% ± 4%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	29% ± 5%	Explore
classical monocyte	6 studies	21% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	30% ± 5%	Explore
T follicular helper cell	6 studies	25% ± 4%	Explore
hematopoietic precursor cell	5 studies	29% ± 12%	Explore
plasmablast	5 studies	38% ± 21%	Explore
exhausted T cell	5 studies	31% ± 3%	Explore
epithelial cell of proximal tubule	5 studies	22% ± 4%	Explore
erythroblast	5 studies	30% ± 13%	Explore
endothelial cell of vascular tree	5 studies	22% ± 4%	Explore
innate lymphoid cell	5 studies	21% ± 5%	Explore
club cell	4 studies	21% ± 6%	Explore
secretory cell	4 studies	26% ± 11%	Explore
vein endothelial cell	4 studies	18% ± 1%	Explore
connective tissue cell	4 studies	22% ± 4%	Explore
pericyte	4 studies	23% ± 3%	Explore
myeloid cell	4 studies	22% ± 9%	Explore
immature B cell	4 studies	18% ± 2%	Explore
precursor B cell	4 studies	28% ± 6%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	30% ± 2%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	29% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	25% ± 6%	Explore
pancreatic A cell	3 studies	30% ± 4%	Explore
leukocyte	3 studies	22% ± 4%	Explore
kidney loop of Henle epithelial cell	3 studies	16% ± 1%	Explore
enterocyte	3 studies	16% ± 1%	Explore
common myeloid progenitor	3 studies	26% ± 12%	Explore
hematopoietic stem cell	3 studies	20% ± 4%	Explore
smooth muscle cell	3 studies	20% ± 3%	Explore
type II pneumocyte	3 studies	28% ± 13%	Explore
intraepithelial lymphocyte	3 studies	30% ± 11%	Explore
type I pneumocyte	3 studies	27% ± 9%	Explore
dendritic cell	3 studies	43% ± 11%	Explore
enteroendocrine cell	3 studies	28% ± 13%	Explore
goblet cell	3 studies	26% ± 11%	Explore
group 3 innate lymphoid cell	3 studies	26% ± 9%	Explore
T-helper 1 cell	3 studies	27% ± 2%	Explore
T-helper 17 cell	3 studies	26% ± 9%	Explore
double negative thymocyte	3 studies	38% ± 12%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	25% ± 4%	Explore
lung	10 studies	23% ± 9%	Explore
kidney	4 studies	21% ± 4%	Explore
lymph node	4 studies	27% ± 6%	Explore
intestine	4 studies	23% ± 10%	Explore
pancreas	3 studies	35% ± 5%	Explore
bone marrow	3 studies	23% ± 4%	Explore
liver	3 studies	32% ± 16%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	1189.63	89 / 89	100%	24.41	901 / 901
liver	100%	1328.32	226 / 226	100%	21.81	406 / 406
ovary	100%	892.42	180 / 180	100%	27.13	430 / 430
uterus	100%	862.55	170 / 170	100%	32.91	459 / 459
esophagus	100%	1231.14	1444 / 1445	100%	24.72	183 / 183
thymus	100%	1098.08	653 / 653	100%	29.31	604 / 605
intestine	100%	1117.37	966 / 966	100%	29.23	526 / 527
skin	100%	1752.62	1809 / 1809	100%	33.45	471 / 472
brain	100%	1130.37	2635 / 2642	100%	28.14	705 / 705
pancreas	100%	767.93	327 / 328	100%	23.51	178 / 178
stomach	100%	1066.55	359 / 359	100%	25.21	285 / 286
prostate	100%	1162.50	245 / 245	100%	34.50	500 / 502
bladder	100%	982.43	21 / 21	99%	29.81	501 / 504
breast	100%	1261.36	459 / 459	99%	29.85	1111 / 1118
adrenal gland	100%	1593.85	258 / 258	99%	24.80	227 / 230
lung	99%	1014.45	570 / 578	100%	25.82	1154 / 1155
adipose	100%	1265.26	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	36.82	80 / 80
lymph node	0%	0	0 / 0	100%	40.35	29 / 29
spleen	100%	1736.44	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	31.68	45 / 45
ureter	0%	0	0 / 0	100%	30.24	1 / 1
muscle	100%	1098.27	802 / 803	0%	0	0 / 0
blood vessel	100%	1079.98	1332 / 1335	0%	0	0 / 0
heart	99%	808.14	855 / 861	0%	0	0 / 0
peripheral blood	85%	707.91	788 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006364	Biological process	rRNA processing
GO_0030490	Biological process	maturation of SSU-rRNA
GO_0042274	Biological process	ribosomal small subunit biogenesis
GO_0005730	Cellular component	nucleolus
GO_0034457	Cellular component	Mpp10 complex
GO_0030684	Cellular component	preribosome
GO_0005634	Cellular component	nucleus
GO_0005654	Cellular component	nucleoplasm
GO_0032040	Cellular component	small-subunit processome
GO_0030515	Molecular function	snoRNA binding
GO_0019843	Molecular function	rRNA binding
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	IMP3
Protein name	U3 small nucleolar ribonucleoprotein protein IMP3 (U3 snoRNP protein IMP3) (BRMS2)
Synonyms	MRPS4 C15orf12
Description	FUNCTION: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing . Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome . .
Accessions	Q9NV31 ENST00000403490.3 ENST00000314852.2

IMP3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review