GTF3A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	36 studies	40% ± 13%	Explore
natural killer cell	36 studies	42% ± 12%	Explore
CD8-positive, alpha-beta T cell	34 studies	41% ± 16%	Explore
CD4-positive, alpha-beta T cell	33 studies	44% ± 14%	Explore
T cell	27 studies	39% ± 13%	Explore
macrophage	27 studies	28% ± 9%	Explore
conventional dendritic cell	27 studies	37% ± 15%	Explore
regulatory T cell	26 studies	39% ± 11%	Explore
classical monocyte	22 studies	29% ± 12%	Explore
non-classical monocyte	21 studies	33% ± 14%	Explore
memory B cell	20 studies	41% ± 8%	Explore
naive B cell	20 studies	36% ± 8%	Explore
plasmacytoid dendritic cell	20 studies	49% ± 12%	Explore
mature NK T cell	19 studies	42% ± 12%	Explore
gamma-delta T cell	18 studies	44% ± 15%	Explore
endothelial cell	18 studies	26% ± 11%	Explore
mucosal invariant T cell	16 studies	44% ± 15%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	16 studies	42% ± 13%	Explore
monocyte	15 studies	31% ± 9%	Explore
endothelial cell of lymphatic vessel	15 studies	31% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	40% ± 15%	Explore
plasma cell	15 studies	45% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	43% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	50% ± 13%	Explore
dendritic cell	13 studies	42% ± 24%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	41% ± 20%	Explore
plasmablast	12 studies	51% ± 21%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	41% ± 14%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	40% ± 11%	Explore
epithelial cell	11 studies	33% ± 19%	Explore
fibroblast	11 studies	24% ± 13%	Explore
mast cell	10 studies	19% ± 2%	Explore
basal cell	10 studies	26% ± 13%	Explore
pericyte	10 studies	20% ± 3%	Explore
myeloid cell	10 studies	29% ± 13%	Explore
ciliated cell	9 studies	31% ± 13%	Explore
smooth muscle cell	8 studies	22% ± 4%	Explore
T follicular helper cell	8 studies	36% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	44% ± 17%	Explore
leukocyte	7 studies	33% ± 11%	Explore
abnormal cell	7 studies	32% ± 12%	Explore
connective tissue cell	7 studies	22% ± 4%	Explore
hematopoietic precursor cell	6 studies	51% ± 28%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	47% ± 15%	Explore
hematopoietic stem cell	6 studies	44% ± 7%	Explore
precursor B cell	6 studies	45% ± 12%	Explore
microglial cell	6 studies	26% ± 12%	Explore
erythrocyte	6 studies	40% ± 24%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	51% ± 15%	Explore
innate lymphoid cell	6 studies	35% ± 11%	Explore
alveolar macrophage	5 studies	27% ± 4%	Explore
CD4-positive helper T cell	5 studies	29% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	35% ± 12%	Explore
exhausted T cell	5 studies	44% ± 14%	Explore
platelet	5 studies	21% ± 4%	Explore
mononuclear phagocyte	5 studies	31% ± 14%	Explore
neuron	5 studies	28% ± 13%	Explore
endothelial cell of artery	5 studies	19% ± 3%	Explore
pro-B cell	5 studies	43% ± 9%	Explore
immature B cell	5 studies	55% ± 18%	Explore
endothelial cell of vascular tree	5 studies	20% ± 4%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	42% ± 14%	Explore
pancreatic A cell	4 studies	37% ± 15%	Explore
epithelial cell of proximal tubule	4 studies	20% ± 3%	Explore
intestinal crypt stem cell	4 studies	21% ± 5%	Explore
progenitor cell	4 studies	39% ± 21%	Explore
vein endothelial cell	4 studies	21% ± 6%	Explore
IgA plasma cell	4 studies	26% ± 9%	Explore
IgG plasma cell	4 studies	34% ± 6%	Explore
transit amplifying cell	4 studies	22% ± 4%	Explore
retinal ganglion cell	4 studies	43% ± 27%	Explore
erythroblast	4 studies	57% ± 13%	Explore
capillary endothelial cell	4 studies	19% ± 1%	Explore
retina horizontal cell	4 studies	29% ± 10%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	26% ± 3%	Explore
glutamatergic neuron	4 studies	41% ± 18%	Explore
granulocyte	4 studies	31% ± 8%	Explore
T-helper 17 cell	4 studies	46% ± 16%	Explore
double negative thymocyte	4 studies	61% ± 16%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	33% ± 14%	Explore
secretory cell	3 studies	29% ± 16%	Explore
type B pancreatic cell	3 studies	43% ± 12%	Explore
neural crest cell	3 studies	24% ± 1%	Explore
common myeloid progenitor	3 studies	44% ± 21%	Explore
lymphocyte	3 studies	42% ± 14%	Explore
megakaryocyte	3 studies	23% ± 7%	Explore
club cell	3 studies	22% ± 8%	Explore
intraepithelial lymphocyte	3 studies	43% ± 19%	Explore
germinal center B cell	3 studies	35% ± 5%	Explore
intermediate monocyte	3 studies	48% ± 23%	Explore
IgM plasma cell	3 studies	37% ± 12%	Explore
GABAergic neuron	3 studies	35% ± 7%	Explore
granulocyte monocyte progenitor cell	3 studies	48% ± 28%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	41% ± 28%	Explore
enteroendocrine cell	3 studies	27% ± 12%	Explore
goblet cell	3 studies	29% ± 12%	Explore
group 3 innate lymphoid cell	3 studies	39% ± 15%	Explore
interneuron	3 studies	27% ± 14%	Explore
oligodendrocyte	3 studies	21% ± 4%	Explore
T-helper 1 cell	3 studies	50% ± 8%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	52% ± 4%	Explore
hepatocyte	3 studies	43% ± 26%	Explore
oligodendrocyte precursor cell	3 studies	19% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	18 studies	44% ± 13%	Explore
lung	16 studies	27% ± 10%	Explore
brain	7 studies	30% ± 9%	Explore
intestine	6 studies	26% ± 8%	Explore
bone marrow	6 studies	26% ± 10%	Explore
lymph node	6 studies	32% ± 9%	Explore
liver	6 studies	34% ± 20%	Explore
kidney	5 studies	26% ± 7%	Explore
breast	4 studies	22% ± 5%	Explore
pancreas	3 studies	44% ± 14%	Explore
eye	3 studies	24% ± 5%	Explore
uterus	3 studies	31% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	4591.81	459 / 459	100%	137.90	1118 / 1118
liver	100%	3940.66	226 / 226	100%	89.83	406 / 406
ovary	100%	1971.06	180 / 180	100%	105.69	430 / 430
pancreas	100%	2966.91	328 / 328	100%	103.87	178 / 178
stomach	100%	3116.99	359 / 359	100%	170.44	286 / 286
uterus	100%	2722.68	170 / 170	100%	114.68	459 / 459
bladder	100%	3997.81	21 / 21	100%	140.96	503 / 504
kidney	100%	3106.30	89 / 89	100%	93.78	899 / 901
brain	100%	3897.33	2635 / 2642	100%	93.56	705 / 705
intestine	100%	3770.87	965 / 966	100%	194.44	526 / 527
lung	100%	3550.66	576 / 578	100%	104.39	1155 / 1155
skin	100%	3782.93	1806 / 1809	100%	131.17	471 / 472
prostate	100%	3332.10	244 / 245	100%	93.78	502 / 502
thymus	100%	2467.35	651 / 653	100%	86.31	604 / 605
esophagus	100%	3689.30	1445 / 1445	99%	88.53	182 / 183
adrenal gland	100%	2998.45	258 / 258	97%	73.05	222 / 230
adipose	100%	5026.94	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	228.78	29 / 29
muscle	100%	8551.82	803 / 803	0%	0	0 / 0
spleen	100%	5127.95	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	96.14	45 / 45
ureter	0%	0	0 / 0	100%	91.27	1 / 1
blood vessel	100%	3150.70	1331 / 1335	0%	0	0 / 0
peripheral blood	100%	4249.34	925 / 929	0%	0	0 / 0
heart	99%	6547.87	854 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	90%	63.48	72 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	GTF3A
Protein name	General transcription factor IIIA Transcription factor IIIA Transcription factor IIIA (TFIIIA)
Synonyms
Description	FUNCTION: Involved in ribosomal large subunit biogenesis. Binds the approximately 50 base pairs internal control region (ICR) of 5S ribosomal RNA genes. It is required for their RNA polymerase III-dependent transcription and may also maintain the transcription of other genes . Also binds the transcribed 5S RNA's (By similarity). .
Accessions	H7BZ51 ENST00000381140 A0A1X7SBT5 ENST00000419181.5 Q92664 H7C326 ENST00000438571.5 H7BZH7 ENST00000435781.5 ENST00000381140.10 [Q92664-1]

GO_0042273	Biological process	ribosomal large subunit biogenesis
GO_0009303	Biological process	rRNA transcription
GO_0006383	Biological process	transcription by RNA polymerase III
GO_0005654	Cellular component	nucleoplasm
GO_0005634	Cellular component	nucleus
GO_0008097	Molecular function	5S rRNA binding
GO_0003677	Molecular function	DNA binding
GO_0046872	Molecular function	metal ion binding

GTF3A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review