CCT5 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	26 studies	22% ± 7%	Explore
endothelial cell	26 studies	29% ± 11%	Explore
natural killer cell	25 studies	25% ± 12%	Explore
conventional dendritic cell	22 studies	28% ± 14%	Explore
macrophage	22 studies	26% ± 10%	Explore
fibroblast	21 studies	25% ± 9%	Explore
classical monocyte	20 studies	26% ± 10%	Explore
T cell	19 studies	25% ± 9%	Explore
non-classical monocyte	19 studies	36% ± 12%	Explore
CD8-positive, alpha-beta T cell	19 studies	31% ± 15%	Explore
smooth muscle cell	18 studies	25% ± 6%	Explore
pericyte	18 studies	27% ± 8%	Explore
basal cell	16 studies	28% ± 13%	Explore
regulatory T cell	16 studies	26% ± 14%	Explore
monocyte	15 studies	25% ± 8%	Explore
endothelial cell of lymphatic vessel	15 studies	36% ± 13%	Explore
CD4-positive, alpha-beta T cell	15 studies	33% ± 19%	Explore
ciliated cell	14 studies	39% ± 12%	Explore
gamma-delta T cell	13 studies	25% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	22% ± 6%	Explore
connective tissue cell	12 studies	29% ± 9%	Explore
epithelial cell	12 studies	39% ± 19%	Explore
mature NK T cell	11 studies	23% ± 6%	Explore
naive B cell	10 studies	22% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	10 studies	21% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	22% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	26% ± 7%	Explore
memory B cell	10 studies	25% ± 12%	Explore
dendritic cell	9 studies	33% ± 18%	Explore
endothelial cell of vascular tree	9 studies	25% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	25% ± 9%	Explore
secretory cell	8 studies	26% ± 11%	Explore
myofibroblast cell	8 studies	28% ± 7%	Explore
abnormal cell	8 studies	31% ± 11%	Explore
neuron	8 studies	35% ± 16%	Explore
endothelial cell of artery	8 studies	22% ± 5%	Explore
vein endothelial cell	8 studies	24% ± 9%	Explore
mucosal invariant T cell	8 studies	22% ± 5%	Explore
myeloid cell	8 studies	27% ± 12%	Explore
plasmablast	7 studies	44% ± 20%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	28% ± 10%	Explore
progenitor cell	7 studies	34% ± 14%	Explore
innate lymphoid cell	7 studies	22% ± 5%	Explore
capillary endothelial cell	7 studies	27% ± 11%	Explore
alveolar macrophage	6 studies	23% ± 3%	Explore
hematopoietic precursor cell	6 studies	39% ± 17%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	38% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	23% ± 6%	Explore
plasma cell	5 studies	39% ± 18%	Explore
erythroblast	5 studies	49% ± 18%	Explore
hematopoietic stem cell	5 studies	32% ± 14%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	28% ± 8%	Explore
glutamatergic neuron	5 studies	33% ± 14%	Explore
oligodendrocyte precursor cell	5 studies	29% ± 6%	Explore
plasmacytoid dendritic cell	5 studies	22% ± 6%	Explore
deuterosomal cell	4 studies	30% ± 4%	Explore
leukocyte	4 studies	29% ± 9%	Explore
exhausted T cell	4 studies	26% ± 8%	Explore
enteroendocrine cell	4 studies	33% ± 11%	Explore
transit amplifying cell	4 studies	21% ± 3%	Explore
immature B cell	4 studies	25% ± 11%	Explore
mesothelial cell	4 studies	32% ± 15%	Explore
precursor B cell	4 studies	39% ± 11%	Explore
pro-B cell	4 studies	34% ± 5%	Explore
erythrocyte	4 studies	42% ± 26%	Explore
T follicular helper cell	4 studies	18% ± 1%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	32% ± 10%	Explore
GABAergic neuron	4 studies	29% ± 9%	Explore
goblet cell	4 studies	29% ± 9%	Explore
interneuron	4 studies	24% ± 11%	Explore
oligodendrocyte	4 studies	23% ± 5%	Explore
mast cell	3 studies	27% ± 12%	Explore
precursor cell	3 studies	56% ± 13%	Explore
respiratory goblet cell	3 studies	31% ± 18%	Explore
mononuclear phagocyte	3 studies	32% ± 11%	Explore
kidney loop of Henle epithelial cell	3 studies	17% ± 2%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	39% ± 17%	Explore
intestinal crypt stem cell	3 studies	22% ± 9%	Explore
neural crest cell	3 studies	43% ± 2%	Explore
retinal ganglion cell	3 studies	43% ± 23%	Explore
extravillous trophoblast	3 studies	30% ± 6%	Explore
placental villous trophoblast	3 studies	44% ± 6%	Explore
common myeloid progenitor	3 studies	32% ± 11%	Explore
lymphocyte	3 studies	42% ± 3%	Explore
club cell	3 studies	28% ± 5%	Explore
type I pneumocyte	3 studies	28% ± 7%	Explore
type II pneumocyte	3 studies	26% ± 11%	Explore
muscle cell	3 studies	28% ± 14%	Explore
germinal center B cell	3 studies	28% ± 11%	Explore
intermediate monocyte	3 studies	39% ± 13%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	25% ± 9%	Explore
granulocyte monocyte progenitor cell	3 studies	41% ± 18%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	54% ± 17%	Explore
group 3 innate lymphoid cell	3 studies	31% ± 18%	Explore
T-helper 17 cell	3 studies	35% ± 26%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	21% ± 6%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	27% ± 12%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	15 studies	26% ± 10%	Explore
peripheral blood	13 studies	26% ± 9%	Explore
brain	9 studies	23% ± 7%	Explore
intestine	6 studies	24% ± 9%	Explore
liver	6 studies	29% ± 18%	Explore
kidney	5 studies	24% ± 6%	Explore
bone marrow	5 studies	23% ± 4%	Explore
lymph node	5 studies	28% ± 17%	Explore
eye	4 studies	21% ± 7%	Explore
uterus	4 studies	30% ± 15%	Explore
breast	4 studies	22% ± 6%	Explore
placenta	3 studies	34% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4942.10	1444 / 1445	100%	129.45	183 / 183
ovary	100%	3714.05	180 / 180	100%	103.25	429 / 430
stomach	100%	3682.31	358 / 359	100%	121.47	286 / 286
breast	100%	5344.54	459 / 459	100%	130.31	1113 / 1118
lung	99%	4685.97	575 / 578	100%	152.43	1154 / 1155
intestine	100%	4359.91	965 / 966	99%	129.61	522 / 527
uterus	100%	4439.56	170 / 170	99%	143.40	453 / 459
skin	100%	7308.63	1808 / 1809	99%	123.24	466 / 472
bladder	100%	4836.24	21 / 21	99%	138.58	497 / 504
prostate	100%	3142.84	245 / 245	97%	68.06	488 / 502
pancreas	98%	2511.02	320 / 328	99%	80.39	176 / 178
thymus	100%	4484.44	653 / 653	96%	56.57	582 / 605
brain	96%	2924.83	2541 / 2642	100%	69.56	702 / 705
kidney	100%	3549.27	89 / 89	94%	58.30	851 / 901
adrenal gland	100%	5753.53	258 / 258	88%	60.88	203 / 230
liver	87%	2184.41	197 / 226	88%	52.29	359 / 406
adipose	100%	5861.35	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	121.28	29 / 29
muscle	100%	5754.30	803 / 803	0%	0	0 / 0
spleen	100%	4479.02	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	129.55	45 / 45
ureter	0%	0	0 / 0	100%	58.35	1 / 1
blood vessel	100%	4334.74	1332 / 1335	0%	0	0 / 0
peripheral blood	94%	5734.31	872 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	94%	62.35	75 / 80
heart	93%	3413.42	802 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007339	Biological process	binding of sperm to zona pellucida
GO_1904871	Biological process	positive regulation of protein localization to Cajal body
GO_0061077	Biological process	chaperone-mediated protein folding
GO_0009615	Biological process	response to virus
GO_1904874	Biological process	positive regulation of telomerase RNA localization to Cajal body
GO_1904851	Biological process	positive regulation of establishment of protein localization to telomere
GO_0006457	Biological process	protein folding
GO_0050821	Biological process	protein stabilization
GO_0032212	Biological process	positive regulation of telomere maintenance via telomerase
GO_0005874	Cellular component	microtubule
GO_0005832	Cellular component	chaperonin-containing T-complex
GO_0005813	Cellular component	centrosome
GO_0070062	Cellular component	extracellular exosome
GO_0005829	Cellular component	cytosol
GO_0044297	Cellular component	cell body
GO_0048487	Molecular function	beta-tubulin binding
GO_0031681	Molecular function	G-protein beta-subunit binding
GO_0048027	Molecular function	mRNA 5'-UTR binding
GO_0044183	Molecular function	protein folding chaperone
GO_0051082	Molecular function	unfolded protein binding
GO_0140662	Molecular function	ATP-dependent protein folding chaperone
GO_0005524	Molecular function	ATP binding
GO_0003730	Molecular function	mRNA 3'-UTR binding
GO_0005515	Molecular function	protein binding
GO_0016887	Molecular function	ATP hydrolysis activity

IV. Literature review

[source]

Gene name	CCT5
Protein name	T-complex protein 1 subunit epsilon (CCT-epsilon) T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) Chaperonin containing TCP1 subunit 5
Synonyms	KIAA0098 CCTE
Description	FUNCTION: Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis . The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance . As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia . The TRiC complex plays a role in the folding of actin and tubulin (Probable). .
Accessions	H0Y958 B7ZAR1 ENST00000503026.5 ENST00000515390.5 ENST00000503454.5 ENST00000280326.9 [P48643-1] H0Y914 P48643 E7ENZ3 ENST00000515676.5 ENST00000506600.1 [P48643-2] D6RIZ7 ENST00000511700.1 E9PCA1 ENST00000625723.1 ENST00000512975.5

CCT5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review