ATXN10 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	29 studies	31% ± 14%	Explore
fibroblast	27 studies	29% ± 12%	Explore
smooth muscle cell	20 studies	26% ± 8%	Explore
astrocyte	19 studies	38% ± 18%	Explore
ciliated cell	17 studies	30% ± 13%	Explore
pericyte	17 studies	30% ± 12%	Explore
oligodendrocyte precursor cell	16 studies	43% ± 18%	Explore
natural killer cell	16 studies	22% ± 7%	Explore
mast cell	14 studies	21% ± 6%	Explore
basal cell	14 studies	39% ± 16%	Explore
macrophage	14 studies	28% ± 13%	Explore
B cell	13 studies	24% ± 7%	Explore
glutamatergic neuron	13 studies	46% ± 24%	Explore
oligodendrocyte	13 studies	37% ± 13%	Explore
epithelial cell	13 studies	36% ± 16%	Explore
CD4-positive, alpha-beta T cell	12 studies	22% ± 8%	Explore
microglial cell	12 studies	37% ± 12%	Explore
CD8-positive, alpha-beta T cell	12 studies	23% ± 8%	Explore
GABAergic neuron	11 studies	45% ± 23%	Explore
endothelial cell of lymphatic vessel	11 studies	26% ± 7%	Explore
T cell	10 studies	25% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	20% ± 5%	Explore
myofibroblast cell	10 studies	32% ± 11%	Explore
dendritic cell	10 studies	29% ± 17%	Explore
adipocyte	10 studies	29% ± 7%	Explore
conventional dendritic cell	9 studies	29% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	20% ± 5%	Explore
connective tissue cell	9 studies	35% ± 13%	Explore
neuron	9 studies	54% ± 17%	Explore
abnormal cell	8 studies	26% ± 15%	Explore
mesothelial cell	8 studies	38% ± 14%	Explore
type I pneumocyte	8 studies	33% ± 10%	Explore
type II pneumocyte	8 studies	34% ± 11%	Explore
regulatory T cell	8 studies	22% ± 6%	Explore
interneuron	7 studies	51% ± 23%	Explore
myeloid cell	7 studies	24% ± 6%	Explore
club cell	7 studies	33% ± 11%	Explore
naive B cell	7 studies	22% ± 5%	Explore
plasma cell	6 studies	26% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	19% ± 2%	Explore
retinal ganglion cell	6 studies	43% ± 22%	Explore
plasmacytoid dendritic cell	6 studies	25% ± 8%	Explore
mucosal invariant T cell	6 studies	18% ± 3%	Explore
hematopoietic precursor cell	5 studies	38% ± 12%	Explore
respiratory goblet cell	5 studies	37% ± 16%	Explore
secretory cell	5 studies	26% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	19% ± 2%	Explore
mature NK T cell	5 studies	23% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	20% ± 4%	Explore
non-classical monocyte	5 studies	26% ± 10%	Explore
kidney loop of Henle epithelial cell	5 studies	19% ± 2%	Explore
progenitor cell	5 studies	36% ± 3%	Explore
retinal bipolar neuron	5 studies	26% ± 9%	Explore
precursor B cell	5 studies	31% ± 6%	Explore
amacrine cell	5 studies	33% ± 13%	Explore
retina horizontal cell	5 studies	33% ± 10%	Explore
retinal rod cell	5 studies	23% ± 4%	Explore
cardiac muscle cell	5 studies	28% ± 2%	Explore
Mueller cell	5 studies	23% ± 7%	Explore
memory B cell	5 studies	18% ± 3%	Explore
endothelial cell of vascular tree	5 studies	22% ± 10%	Explore
gamma-delta T cell	5 studies	29% ± 22%	Explore
plasmablast	4 studies	44% ± 15%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	21% ± 5%	Explore
precursor cell	4 studies	39% ± 12%	Explore
vein endothelial cell	4 studies	22% ± 8%	Explore
glial cell	4 studies	35% ± 17%	Explore
granule cell	4 studies	38% ± 14%	Explore
capillary endothelial cell	4 studies	27% ± 8%	Explore
immature B cell	4 studies	24% ± 8%	Explore
pro-B cell	4 studies	33% ± 5%	Explore
retinal pigment epithelial cell	4 studies	39% ± 10%	Explore
lymphocyte	4 studies	28% ± 4%	Explore
OFF-bipolar cell	4 studies	27% ± 4%	Explore
ON-bipolar cell	4 studies	29% ± 5%	Explore
T follicular helper cell	4 studies	18% ± 1%	Explore
hepatocyte	4 studies	55% ± 19%	Explore
hematopoietic stem cell	4 studies	21% ± 7%	Explore
enteroendocrine cell	4 studies	28% ± 14%	Explore
leukocyte	4 studies	24% ± 5%	Explore
monocyte	4 studies	25% ± 6%	Explore
goblet cell	4 studies	28% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	22% ± 7%	Explore
renal principal cell	4 studies	20% ± 5%	Explore
pancreatic A cell	3 studies	50% ± 15%	Explore
type B pancreatic cell	3 studies	40% ± 15%	Explore
classical monocyte	3 studies	28% ± 6%	Explore
podocyte	3 studies	40% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	31% ± 10%	Explore
epithelial cell of proximal tubule	3 studies	19% ± 2%	Explore
neural crest cell	3 studies	30% ± 6%	Explore
GABAergic interneuron	3 studies	44% ± 4%	Explore
mononuclear phagocyte	3 studies	27% ± 9%	Explore
GABAergic amacrine cell	3 studies	31% ± 1%	Explore
glycinergic amacrine cell	3 studies	30% ± 2%	Explore
rod bipolar cell	3 studies	34% ± 1%	Explore
exhausted T cell	3 studies	20% ± 1%	Explore
cholangiocyte	3 studies	57% ± 12%	Explore
neural progenitor cell	3 studies	36% ± 5%	Explore
ependymal cell	3 studies	41% ± 17%	Explore
granulocyte monocyte progenitor cell	3 studies	28% ± 10%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	43% ± 20%	Explore
intestinal crypt stem cell	3 studies	22% ± 6%	Explore
adventitial cell	3 studies	25% ± 2%	Explore
chondrocyte	3 studies	35% ± 2%	Explore
transit amplifying cell	3 studies	39% ± 23%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	16% ± 2%	Explore
mucus secreting cell	3 studies	26% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	18 studies	42% ± 20%	Explore
lung	12 studies	29% ± 13%	Explore
peripheral blood	8 studies	21% ± 8%	Explore
eye	8 studies	28% ± 11%	Explore
kidney	6 studies	22% ± 4%	Explore
intestine	6 studies	22% ± 11%	Explore
heart	5 studies	23% ± 4%	Explore
liver	5 studies	35% ± 19%	Explore
lymph node	4 studies	18% ± 2%	Explore
adipose	4 studies	29% ± 11%	Explore
pancreas	3 studies	44% ± 13%	Explore
bone marrow	3 studies	22% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	6203.86	2642 / 2642	100%	110.63	705 / 705
esophagus	100%	4155.85	1445 / 1445	100%	46.33	183 / 183
lung	100%	4358.93	578 / 578	100%	69.64	1155 / 1155
ovary	100%	5851.28	180 / 180	100%	44.15	430 / 430
breast	100%	4531.23	459 / 459	100%	86.41	1117 / 1118
prostate	100%	4968.76	245 / 245	100%	89.72	501 / 502
pancreas	100%	3025.97	327 / 328	100%	49.67	178 / 178
bladder	100%	5007.81	21 / 21	100%	62.50	502 / 504
uterus	100%	5638.61	170 / 170	100%	69.16	457 / 459
thymus	100%	4944.88	653 / 653	99%	71.09	601 / 605
stomach	100%	3262.80	359 / 359	99%	40.86	284 / 286
intestine	100%	4118.51	965 / 966	99%	45.05	522 / 527
liver	100%	2773.49	225 / 226	99%	50.42	402 / 406
kidney	100%	3931.93	89 / 89	98%	47.50	886 / 901
skin	100%	4604.28	1808 / 1809	98%	74.61	462 / 472
adrenal gland	100%	6681.80	258 / 258	94%	57.90	216 / 230
adipose	100%	4331.72	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	65.65	29 / 29
muscle	100%	4235.06	803 / 803	0%	0	0 / 0
spleen	100%	3590.90	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	62.73	45 / 45
ureter	0%	0	0 / 0	100%	39.87	1 / 1
blood vessel	100%	4611.03	1334 / 1335	0%	0	0 / 0
heart	96%	4313.82	823 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	95%	48.33	76 / 80
peripheral blood	75%	2605.87	700 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0060271	Biological process	cilium assembly
GO_0007399	Biological process	nervous system development
GO_0051301	Biological process	cell division
GO_0032465	Biological process	regulation of cytokinesis
GO_0031175	Biological process	neuron projection development
GO_0005814	Cellular component	centriole
GO_0005615	Cellular component	extracellular space
GO_0036064	Cellular component	ciliary basal body
GO_0030496	Cellular component	midbody
GO_0005829	Cellular component	cytosol
GO_0030425	Cellular component	dendrite
GO_0043025	Cellular component	neuronal cell body
GO_0005886	Cellular component	plasma membrane
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0016020	Cellular component	membrane
GO_0005737	Cellular component	cytoplasm
GO_0005515	Molecular function	protein binding

Gene name	ATXN10
Protein name	Ataxin 10 Ataxin-10 (Brain protein E46 homolog) (Spinocerebellar ataxia type 10 protein)
Synonyms	SCA10
Description	FUNCTION: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. .
Accessions	ENST00000252934.10 [Q9UBB4-1] ENST00000381061.8 [Q9UBB4-2] B1AHE4 Q9UBB4 ENST00000402380.3 B1AHE3 ENST00000435026.5

ATXN10 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review