GO_0002755 | MyD88-dependent toll-like receptor signaling pathway | OmnibusX

MyD88-dependent toll-like receptor signaling pathway

I. Involved cell types

	Genes	Cell types	No. of supported studies
Group 1	TRAF6 IKBKB MAP3K7 HSPD1	dopaminergic neuron GABAergic neuron glutamatergic neuron	6 studies
Group 2	IRAK3 IRAK4 IRAK1 TNIP1 MYD88	epithelial cell myeloid cell	5 studies
Group 3	TLR4 BTK	myeloid cell	9 studies
Group 4	IRAK2	myeloid cell transit amplifying cell	13 studies

II. Literature review

Name	MyD88-dependent toll-like receptor signaling pathway
ID	GO_0002755
collection_id	Biological process
Exact synonym	MyD88-dependent TLR signaling pathway, MyD88-dependent toll-like receptor signalling pathway
Description	A toll-like receptor signaling pathway in which the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.
External URL
Genes	REG3G TRAF6 TIRAP IRAK4 HSPD1 MAP3K7 IRAK2 MYD88 IRAK1 TLR6 IRAK3 TLR9 IKBKB BTK TNIP1 TLR4 tlr4_tlr6_human