STMN1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
plasmacytoid dendritic cell	25 studies	66% ± 16%	Explore
macrophage	24 studies	33% ± 18%	Explore
endothelial cell	24 studies	43% ± 25%	Explore
mast cell	23 studies	42% ± 18%	Explore
endothelial cell of lymphatic vessel	22 studies	68% ± 18%	Explore
T cell	21 studies	50% ± 31%	Explore
B cell	17 studies	38% ± 22%	Explore
fibroblast	17 studies	42% ± 24%	Explore
basal cell	15 studies	31% ± 14%	Explore
CD8-positive, alpha-beta T cell	15 studies	50% ± 28%	Explore
natural killer cell	15 studies	45% ± 27%	Explore
oligodendrocyte	13 studies	39% ± 17%	Explore
conventional dendritic cell	13 studies	31% ± 18%	Explore
smooth muscle cell	13 studies	50% ± 30%	Explore
epithelial cell	12 studies	53% ± 27%	Explore
connective tissue cell	12 studies	57% ± 27%	Explore
glutamatergic neuron	11 studies	53% ± 25%	Explore
endothelial cell of artery	11 studies	48% ± 21%	Explore
astrocyte	11 studies	38% ± 20%	Explore
CD4-positive, alpha-beta T cell	10 studies	58% ± 30%	Explore
pericyte	10 studies	51% ± 26%	Explore
progenitor cell	9 studies	69% ± 25%	Explore
neuron	9 studies	67% ± 29%	Explore
regulatory T cell	9 studies	36% ± 20%	Explore
plasmablast	8 studies	55% ± 23%	Explore
capillary endothelial cell	8 studies	35% ± 28%	Explore
abnormal cell	8 studies	40% ± 24%	Explore
microglial cell	8 studies	21% ± 4%	Explore
naive B cell	8 studies	23% ± 12%	Explore
dendritic cell	8 studies	32% ± 17%	Explore
myeloid cell	8 studies	41% ± 24%	Explore
gamma-delta T cell	8 studies	33% ± 25%	Explore
oligodendrocyte precursor cell	8 studies	43% ± 25%	Explore
interneuron	7 studies	56% ± 23%	Explore
hematopoietic stem cell	7 studies	73% ± 13%	Explore
brush cell	7 studies	51% ± 33%	Explore
GABAergic neuron	7 studies	50% ± 22%	Explore
kidney loop of Henle epithelial cell	6 studies	30% ± 9%	Explore
myofibroblast cell	6 studies	79% ± 14%	Explore
monocyte	6 studies	41% ± 14%	Explore
enteroendocrine cell	6 studies	60% ± 23%	Explore
leukocyte	6 studies	42% ± 23%	Explore
mesothelial cell	6 studies	78% ± 22%	Explore
transit amplifying cell	6 studies	45% ± 23%	Explore
amacrine cell	6 studies	57% ± 24%	Explore
retinal ganglion cell	6 studies	63% ± 26%	Explore
retinal rod cell	6 studies	40% ± 19%	Explore
retinal cone cell	6 studies	60% ± 30%	Explore
precursor B cell	6 studies	76% ± 16%	Explore
endothelial cell of vascular tree	6 studies	26% ± 4%	Explore
plasma cell	6 studies	45% ± 9%	Explore
ciliated cell	6 studies	41% ± 12%	Explore
retina horizontal cell	6 studies	54% ± 26%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	51% ± 25%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	21% ± 4%	Explore
hematopoietic precursor cell	5 studies	74% ± 18%	Explore
innate lymphoid cell	5 studies	44% ± 24%	Explore
erythroblast	5 studies	69% ± 21%	Explore
vein endothelial cell	5 studies	54% ± 30%	Explore
OFF-bipolar cell	5 studies	64% ± 23%	Explore
ON-bipolar cell	5 studies	54% ± 19%	Explore
pro-B cell	5 studies	77% ± 16%	Explore
immature B cell	5 studies	49% ± 26%	Explore
erythrocyte	5 studies	56% ± 29%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	38% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	27% ± 8%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	33% ± 13%	Explore
alveolar macrophage	4 studies	33% ± 6%	Explore
type I pneumocyte	4 studies	43% ± 28%	Explore
deuterosomal cell	4 studies	29% ± 2%	Explore
pancreatic A cell	4 studies	45% ± 18%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	68% ± 30%	Explore
mature NK T cell	4 studies	22% ± 10%	Explore
epithelial cell of proximal tubule	4 studies	39% ± 28%	Explore
goblet cell	4 studies	31% ± 11%	Explore
intestinal crypt stem cell	4 studies	31% ± 11%	Explore
retinal bipolar neuron	4 studies	67% ± 26%	Explore
GABAergic amacrine cell	4 studies	59% ± 16%	Explore
glycinergic amacrine cell	4 studies	55% ± 19%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	24% ± 7%	Explore
Mueller cell	4 studies	42% ± 14%	Explore
germinal center B cell	4 studies	45% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	23% ± 6%	Explore
memory B cell	4 studies	27% ± 9%	Explore
granulocyte	4 studies	52% ± 21%	Explore
melanocyte	4 studies	44% ± 18%	Explore
pancreatic D cell	3 studies	36% ± 16%	Explore
mononuclear phagocyte	3 studies	27% ± 8%	Explore
neural crest cell	3 studies	87% ± 17%	Explore
extravillous trophoblast	3 studies	54% ± 19%	Explore
lymphocyte	3 studies	65% ± 20%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	18% ± 1%	Explore
Schwann cell	3 studies	71% ± 23%	Explore
precursor cell	3 studies	73% ± 21%	Explore
secretory cell	3 studies	41% ± 18%	Explore
rod bipolar cell	3 studies	53% ± 23%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	33% ± 12%	Explore
myoepithelial cell	3 studies	56% ± 19%	Explore
neural progenitor cell	3 studies	33% ± 10%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	88% ± 9%	Explore
glial cell	3 studies	55% ± 28%	Explore
group 3 innate lymphoid cell	3 studies	44% ± 25%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	19% ± 2%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	32% ± 11%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	31% ± 14%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	14 studies	43% ± 17%	Explore
lung	12 studies	34% ± 18%	Explore
eye	9 studies	52% ± 14%	Explore
kidney	6 studies	36% ± 22%	Explore
pancreas	4 studies	38% ± 10%	Explore
intestine	4 studies	61% ± 7%	Explore
bone marrow	4 studies	40% ± 14%	Explore
liver	4 studies	39% ± 22%	Explore
lymph node	4 studies	38% ± 26%	Explore
peripheral blood	3 studies	30% ± 9%	Explore
placenta	3 studies	41% ± 10%	Explore
adrenal gland	3 studies	31% ± 15%	Explore
thymus	3 studies	71% ± 33%	Explore
breast	3 studies	24% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	24779.74	2630 / 2642	100%	190.15	705 / 705
ovary	97%	7747.33	174 / 180	98%	112.87	420 / 430
uterus	90%	4834.72	153 / 170	99%	243.20	456 / 459
intestine	84%	3329.75	812 / 966	93%	83.01	489 / 527
skin	68%	5125.61	1237 / 1809	99%	174.98	466 / 472
lung	69%	2574.64	396 / 578	92%	98.23	1066 / 1155
breast	63%	2024.36	288 / 459	97%	118.28	1089 / 1118
esophagus	56%	2462.51	807 / 1445	92%	79.59	168 / 183
stomach	42%	1482.67	149 / 359	91%	69.85	260 / 286
bladder	29%	702.81	6 / 21	97%	144.06	491 / 504
kidney	61%	2268.76	54 / 89	59%	25.55	532 / 901
thymus	28%	817.53	186 / 653	83%	130.82	504 / 605
adrenal gland	17%	525.60	44 / 258	83%	84.70	191 / 230
lymph node	0%	0	0 / 0	100%	170.95	29 / 29
tonsil	0%	0	0 / 0	100%	203.42	45 / 45
ureter	0%	0	0 / 0	100%	132.09	1 / 1
pancreas	2%	57.12	5 / 328	90%	62.24	160 / 178
spleen	83%	3427.01	200 / 241	0%	0	0 / 0
eye	0%	0	0 / 0	74%	40.58	59 / 80
prostate	25%	695.37	61 / 245	43%	18.98	217 / 502
liver	4%	176.13	10 / 226	53%	31.72	215 / 406
adipose	56%	1876.08	675 / 1204	0%	0	0 / 0
blood vessel	41%	1290.99	554 / 1335	0%	0	0 / 0
peripheral blood	30%	4337.51	280 / 929	0%	0	0 / 0
heart	13%	390.79	109 / 861	0%	0	0 / 0
muscle	2%	62.95	19 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0035024	Biological process	negative regulation of Rho protein signal transduction
GO_0007019	Biological process	microtubule depolymerization
GO_1905098	Biological process	negative regulation of guanyl-nucleotide exchange factor activity
GO_0061436	Biological process	establishment of skin barrier
GO_0007052	Biological process	mitotic spindle organization
GO_0031175	Biological process	neuron projection development
GO_0031115	Biological process	negative regulation of microtubule polymerization
GO_0007165	Biological process	signal transduction
GO_0009615	Biological process	response to virus
GO_0031110	Biological process	regulation of microtubule polymerization or depolymerization
GO_0000281	Biological process	mitotic cytokinesis
GO_0007409	Biological process	axonogenesis
GO_0035556	Biological process	intracellular signal transduction
GO_0030334	Biological process	regulation of cell migration
GO_0070495	Biological process	negative regulation of thrombin-activated receptor signaling pathway
GO_0048012	Biological process	hepatocyte growth factor receptor signaling pathway
GO_0051497	Biological process	negative regulation of stress fiber assembly
GO_0005874	Cellular component	microtubule
GO_0016020	Cellular component	membrane
GO_0070062	Cellular component	extracellular exosome
GO_0043005	Cellular component	neuron projection
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0015631	Molecular function	tubulin binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	STMN1
Protein name	Stathmin (Leukemia-associated phosphoprotein p18) (Metablastin) (Oncoprotein 18) (Op18) (Phosphoprotein p19) (pp19) (Prosolin) (Protein Pr22) (pp17) Stathmin
Synonyms	OP18 LAP18 C1orf215
Description	FUNCTION: Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity). .
Accessions	ENST00000357865.6 [P16949-1] Q96CE4 ENST00000374291.5 [P16949-1] ENST00000455785.7 [P16949-1] B5BU83 P16949 ENST00000399728.5 [P16949-1] ENST00000426559.6 [P16949-2] ENST00000446334.1 A2A2D0

STMN1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review