Biological process

down regulation of GDP-dissociation stimulator activity, down regulation of GDS, down regulation of GEF, down regulation of guanyl-nucleotide exchange factor activity, down regulation of guanyl-nucleotide release factor activity, down regulation of guanyl-nucleotide releasing factor, down-regulation of GDP-dissociation stimulator activity, down-regulation of GDS, down-regulation of GEF, down-regulation of guanyl-nucleotide exchange factor activity, down-regulation of guanyl-nucleotide release factor activity, down-regulation of guanyl-nucleotide releasing factor, downregulation of GDP-dissociation stimulator activity, downregulation of GDS, downregulation of GEF, downregulation of guanyl-nucleotide exchange factor activity, downregulation of guanyl-nucleotide release factor activity, downregulation of guanyl-nucleotide releasing factor, negative regulation of GDP-dissociation stimulator activity, negative regulation of GDS, negative regulation of GEF, negative regulation of guanyl-nucleotide release factor activity, negative regulation of guanyl-nucleotide releasing factor

Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity.