SSNA1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	30 studies	27% ± 9%	Explore
T cell	22 studies	23% ± 8%	Explore
CD4-positive, alpha-beta T cell	21 studies	27% ± 12%	Explore
B cell	20 studies	26% ± 8%	Explore
CD8-positive, alpha-beta T cell	20 studies	30% ± 12%	Explore
regulatory T cell	19 studies	27% ± 7%	Explore
non-classical monocyte	18 studies	32% ± 16%	Explore
macrophage	16 studies	22% ± 9%	Explore
endothelial cell	15 studies	26% ± 12%	Explore
memory B cell	14 studies	21% ± 4%	Explore
classical monocyte	14 studies	27% ± 12%	Explore
naive B cell	14 studies	20% ± 3%	Explore
conventional dendritic cell	13 studies	28% ± 16%	Explore
ciliated cell	13 studies	34% ± 17%	Explore
gamma-delta T cell	13 studies	28% ± 12%	Explore
monocyte	12 studies	21% ± 6%	Explore
epithelial cell	12 studies	34% ± 21%	Explore
plasmacytoid dendritic cell	12 studies	29% ± 11%	Explore
plasma cell	11 studies	28% ± 11%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	11 studies	21% ± 5%	Explore
fibroblast	11 studies	23% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	31% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	26% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	28% ± 6%	Explore
mature NK T cell	10 studies	25% ± 7%	Explore
pericyte	10 studies	22% ± 6%	Explore
smooth muscle cell	10 studies	22% ± 4%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	29% ± 12%	Explore
mucosal invariant T cell	9 studies	23% ± 4%	Explore
type I pneumocyte	8 studies	25% ± 11%	Explore
dendritic cell	8 studies	37% ± 25%	Explore
plasmablast	7 studies	42% ± 23%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	28% ± 8%	Explore
basal cell	7 studies	37% ± 18%	Explore
abnormal cell	7 studies	25% ± 6%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	34% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	29% ± 6%	Explore
oligodendrocyte	6 studies	22% ± 7%	Explore
myofibroblast cell	6 studies	22% ± 2%	Explore
endothelial cell of lymphatic vessel	6 studies	27% ± 8%	Explore
T follicular helper cell	6 studies	23% ± 5%	Explore
epithelial cell of proximal tubule	5 studies	19% ± 2%	Explore
neuron	5 studies	26% ± 16%	Explore
enterocyte	5 studies	19% ± 4%	Explore
precursor B cell	5 studies	32% ± 7%	Explore
connective tissue cell	5 studies	25% ± 9%	Explore
myeloid cell	5 studies	26% ± 12%	Explore
club cell	5 studies	21% ± 7%	Explore
type II pneumocyte	5 studies	30% ± 16%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	31% ± 10%	Explore
innate lymphoid cell	5 studies	22% ± 6%	Explore
erythrocyte	5 studies	31% ± 18%	Explore
hematopoietic precursor cell	4 studies	36% ± 15%	Explore
leukocyte	4 studies	27% ± 8%	Explore
exhausted T cell	4 studies	40% ± 11%	Explore
goblet cell	4 studies	28% ± 17%	Explore
mesothelial cell	4 studies	27% ± 17%	Explore
pro-B cell	4 studies	27% ± 5%	Explore
immature B cell	4 studies	24% ± 7%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	34% ± 3%	Explore
endothelial cell of vascular tree	4 studies	18% ± 2%	Explore
T-helper 17 cell	4 studies	26% ± 15%	Explore
deuterosomal cell	3 studies	27% ± 5%	Explore
pancreatic A cell	3 studies	24% ± 11%	Explore
endothelial cell of artery	3 studies	21% ± 3%	Explore
neural crest cell	3 studies	21% ± 1%	Explore
vein endothelial cell	3 studies	19% ± 3%	Explore
transit amplifying cell	3 studies	20% ± 1%	Explore
erythroblast	3 studies	39% ± 25%	Explore
lymphocyte	3 studies	31% ± 11%	Explore
capillary endothelial cell	3 studies	24% ± 6%	Explore
intraepithelial lymphocyte	3 studies	28% ± 7%	Explore
Mueller cell	3 studies	21% ± 4%	Explore
germinal center B cell	3 studies	25% ± 1%	Explore
intermediate monocyte	3 studies	37% ± 17%	Explore
glutamatergic neuron	3 studies	32% ± 6%	Explore
enteroendocrine cell	3 studies	33% ± 16%	Explore
group 3 innate lymphoid cell	3 studies	28% ± 13%	Explore
T-helper 1 cell	3 studies	30% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	24% ± 4%	Explore
double negative thymocyte	3 studies	36% ± 15%	Explore
oligodendrocyte precursor cell	3 studies	23% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	27% ± 9%	Explore
lung	10 studies	28% ± 13%	Explore
intestine	7 studies	23% ± 12%	Explore
brain	6 studies	22% ± 6%	Explore
lymph node	5 studies	22% ± 5%	Explore
kidney	4 studies	22% ± 4%	Explore
bone marrow	3 studies	19% ± 4%	Explore
eye	3 studies	23% ± 6%	Explore
liver	3 studies	37% ± 26%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	2179.83	258 / 258	100%	116.85	230 / 230
esophagus	100%	2568.34	1445 / 1445	100%	108.77	183 / 183
ovary	100%	1329.68	180 / 180	100%	132.12	430 / 430
pancreas	100%	1836.35	328 / 328	100%	140.21	178 / 178
thymus	100%	1908.66	653 / 653	100%	150.08	605 / 605
uterus	100%	1862.71	170 / 170	100%	193.42	459 / 459
brain	100%	2054.15	2639 / 2642	100%	134.45	705 / 705
liver	100%	1590.57	226 / 226	100%	116.71	405 / 406
intestine	100%	2268.82	966 / 966	99%	163.54	524 / 527
stomach	100%	2234.20	359 / 359	99%	138.31	284 / 286
prostate	100%	2458.96	245 / 245	99%	182.02	498 / 502
skin	100%	2441.27	1809 / 1809	99%	151.87	468 / 472
kidney	100%	2429.62	89 / 89	99%	108.42	893 / 901
breast	100%	2033.19	459 / 459	99%	149.47	1102 / 1118
bladder	100%	2222.62	21 / 21	98%	178.06	496 / 504
lung	99%	1893.89	575 / 578	99%	132.65	1140 / 1155
adipose	100%	1914.50	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	198.43	80 / 80
lymph node	0%	0	0 / 0	100%	277.44	29 / 29
spleen	100%	2484.73	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	194.08	45 / 45
ureter	0%	0	0 / 0	100%	289.42	1 / 1
heart	100%	1884.80	859 / 861	0%	0	0 / 0
muscle	100%	1897.94	801 / 803	0%	0	0 / 0
blood vessel	100%	1818.47	1331 / 1335	0%	0	0 / 0
peripheral blood	99%	1851.10	920 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0051301	Biological process	cell division
GO_0007020	Biological process	microtubule nucleation
GO_0140060	Biological process	axon arborization
GO_0043113	Biological process	receptor clustering
GO_0007409	Biological process	axonogenesis
GO_0000226	Biological process	microtubule cytoskeleton organization
GO_0048675	Biological process	axon extension
GO_0042073	Biological process	intraciliary transport
GO_0099512	Cellular component	supramolecular fiber
GO_0030496	Cellular component	midbody
GO_0005886	Cellular component	plasma membrane
GO_0005813	Cellular component	centrosome
GO_0031514	Cellular component	motile cilium
GO_0005814	Cellular component	centriole
GO_0005930	Cellular component	axoneme
GO_0005829	Cellular component	cytosol
GO_0030424	Cellular component	axon
GO_0036064	Cellular component	ciliary basal body
GO_0005634	Cellular component	nucleus
GO_0042802	Molecular function	identical protein binding
GO_0008017	Molecular function	microtubule binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	SSNA1
Protein name	SS nuclear autoantigen 1 Microtubule nucleation factor SSNA1 (Nuclear autoantigen of 14 kDa) (Sjoegren syndrome nuclear autoantigen 1)
Synonyms	NA14
Description	FUNCTION: Microtubule-binding protein which stabilizes dynamic microtubules by slowing growth and shrinkage at both plus and minus ends and serves as a sensor of microtubule damage, protecting microtubules from the microtubule-severing enzyme SPAST . Induces microtubule branching which is mediated by the formation of long SSNA1 fibrils which guide microtubule protofilaments to split apart from the mother microtubule and form daughter microtubules (By similarity). Plays a role in axon outgrowth and branching . Required for cell division . .
Accessions	ENST00000322310.10 ENST00000464553.2 O43805 A0A087WV26

SSNA1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review