Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 18 studies | 29% ± 11% | |
peripheral blood | 10 studies | 30% ± 16% | |
brain | 10 studies | 36% ± 16% | |
intestine | 7 studies | 27% ± 10% | |
liver | 7 studies | 35% ± 12% | |
kidney | 7 studies | 22% ± 2% | |
heart | 5 studies | 22% ± 5% | |
uterus | 5 studies | 40% ± 15% | |
adipose | 5 studies | 29% ± 13% | |
bone marrow | 4 studies | 22% ± 6% | |
eye | 4 studies | 39% ± 17% | |
esophagus | 4 studies | 32% ± 17% | |
breast | 4 studies | 38% ± 17% | |
prostate | 4 studies | 21% ± 3% | |
placenta | 3 studies | 31% ± 16% | |
adrenal gland | 3 studies | 20% ± 3% | |
thymus | 3 studies | 33% ± 8% | |
lymph node | 3 studies | 27% ± 3% | |
skin | 3 studies | 47% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 16841.89 | 1444 / 1445 | 100% | 210.14 | 183 / 183 |
lung | 100% | 29979.32 | 578 / 578 | 100% | 137.86 | 1153 / 1155 |
uterus | 100% | 24030.21 | 170 / 170 | 100% | 163.97 | 457 / 459 |
ovary | 100% | 23866.42 | 180 / 180 | 100% | 114.99 | 428 / 430 |
breast | 100% | 17978.17 | 458 / 459 | 100% | 121.37 | 1113 / 1118 |
bladder | 100% | 16500.05 | 21 / 21 | 99% | 158.60 | 498 / 504 |
prostate | 99% | 14048.97 | 243 / 245 | 99% | 72.98 | 495 / 502 |
thymus | 100% | 17330.43 | 652 / 653 | 97% | 69.73 | 589 / 605 |
intestine | 100% | 14547.20 | 964 / 966 | 97% | 76.12 | 510 / 527 |
stomach | 99% | 12646.38 | 356 / 359 | 96% | 75.44 | 275 / 286 |
kidney | 97% | 8822.81 | 86 / 89 | 98% | 97.28 | 885 / 901 |
pancreas | 95% | 7530.13 | 312 / 328 | 98% | 103.54 | 175 / 178 |
adrenal gland | 100% | 22408.41 | 257 / 258 | 93% | 64.98 | 215 / 230 |
skin | 100% | 47177.55 | 1809 / 1809 | 93% | 114.11 | 438 / 472 |
liver | 97% | 18467.47 | 219 / 226 | 95% | 90.26 | 386 / 406 |
brain | 66% | 4465.21 | 1737 / 2642 | 99% | 83.17 | 701 / 705 |
blood vessel | 100% | 21225.51 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 12614.08 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 183.86 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 63.21 | 1 / 1 |
adipose | 100% | 23237.83 | 1203 / 1204 | 0% | 0 | 0 / 0 |
muscle | 99% | 15510.06 | 792 / 803 | 0% | 0 | 0 / 0 |
heart | 89% | 9697.03 | 769 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 76% | 40.59 | 22 / 29 |
peripheral blood | 57% | 5638.46 | 530 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 54% | 27.33 | 43 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_1903841 | Biological process | cellular response to arsenite(3-) |
GO_0071260 | Biological process | cellular response to mechanical stimulus |
GO_1903812 | Biological process | L-serine import across plasma membrane |
GO_0006868 | Biological process | glutamine transport |
GO_0033120 | Biological process | positive regulation of RNA splicing |
GO_0150104 | Biological process | transport across blood-brain barrier |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0031460 | Biological process | glycine betaine transport |
GO_0007565 | Biological process | female pregnancy |
GO_0032328 | Biological process | alanine transport |
GO_0014850 | Biological process | response to muscle activity |
GO_0015804 | Biological process | neutral amino acid transport |
GO_0034198 | Biological process | cellular response to amino acid starvation |
GO_0003333 | Biological process | amino acid transmembrane transport |
GO_0006836 | Biological process | neurotransmitter transport |
GO_0015824 | Biological process | proline transport |
GO_1903294 | Biological process | regulation of glutamate secretion, neurotransmission |
GO_0015825 | Biological process | L-serine transport |
GO_0006865 | Biological process | amino acid transport |
GO_0021987 | Biological process | cerebral cortex development |
GO_0080135 | Biological process | regulation of cellular response to stress |
GO_1903803 | Biological process | L-glutamine import across plasma membrane |
GO_1904271 | Biological process | L-proline import across plasma membrane |
GO_0043090 | Biological process | amino acid import |
GO_0035725 | Biological process | sodium ion transmembrane transport |
GO_0015800 | Biological process | acidic amino acid transport |
GO_0005903 | Cellular component | brush border |
GO_0005886 | Cellular component | plasma membrane |
GO_0042383 | Cellular component | sarcolemma |
GO_0043025 | Cellular component | neuronal cell body |
GO_0030425 | Cellular component | dendrite |
GO_0005737 | Cellular component | cytoplasm |
GO_0030424 | Cellular component | axon |
GO_0015172 | Molecular function | acidic amino acid transmembrane transporter activity |
GO_0005283 | Molecular function | amino acid:sodium symporter activity |
GO_0015171 | Molecular function | amino acid transmembrane transporter activity |
GO_0015655 | Molecular function | alanine:sodium symporter activity |
GO_0015194 | Molecular function | L-serine transmembrane transporter activity |
GO_0015186 | Molecular function | L-glutamine transmembrane transporter activity |
GO_0005298 | Molecular function | proline:sodium symporter activity |
GO_0005515 | Molecular function | protein binding |
GO_0005295 | Molecular function | neutral L-amino acid:sodium symporter activity |
Gene name | SLC38A2 |
Protein name | Solute carrier family 38 member 2 Sodium-coupled neutral amino acid symporter 2 (Amino acid transporter A2) (Solute carrier family 38 member 2) (System A amino acid transporter 2) (System A transporter 1) (System N amino acid transporter 2) Sodium-coupled neutral amino acid symporter 2 (Amino acid transporter A2) (Protein 40-9-1) (Solute carrier family 38 member 2) (System A amino acid transporter 2) (System A transporter 1) (System N amino acid transporter 2) |
Synonyms | SAT2 SNAT2 KIAA1382 ATA2 |
Description | FUNCTION: Symporter that cotransports neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane . The trasnport is pH-sensitive, Li(+)-intolerant, electrogenic, driven by the Na(+) electrochemical gradient and cotransports of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier . May function in the transport of amino acids in the supply of maternal nutrients to the fetus through the placenta (By similarity). Maintains a key metabolic glutamine/glutamate balance underpinning retrograde signaling by dendritic release of the neurotransmitter glutamate (By similarity). Transports L-proline in differentiating osteoblasts for the efficient synthesis of proline-enriched proteins and provides proline essential for osteoblast differentiation and bone formation during bone development (By similarity). . |
Accessions | ENST00000612232.1 [Q96QD8-2] Q96QD8 ENST00000549258.5 ENST00000551374.5 F8VQW8 F8VUY8 ENST00000256689.10 [Q96QD8-1] |