RTF2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	25 studies	24% ± 6%	Explore
endothelial cell	25 studies	26% ± 12%	Explore
conventional dendritic cell	23 studies	28% ± 14%	Explore
macrophage	20 studies	23% ± 9%	Explore
classical monocyte	19 studies	24% ± 11%	Explore
B cell	18 studies	21% ± 7%	Explore
smooth muscle cell	17 studies	23% ± 6%	Explore
pericyte	16 studies	23% ± 6%	Explore
regulatory T cell	16 studies	21% ± 4%	Explore
CD8-positive, alpha-beta T cell	15 studies	24% ± 6%	Explore
fibroblast	15 studies	26% ± 11%	Explore
monocyte	14 studies	22% ± 7%	Explore
CD4-positive, alpha-beta T cell	14 studies	22% ± 6%	Explore
naive B cell	13 studies	18% ± 3%	Explore
non-classical monocyte	13 studies	29% ± 13%	Explore
plasmacytoid dendritic cell	13 studies	32% ± 10%	Explore
T cell	12 studies	21% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	26% ± 6%	Explore
mature NK T cell	11 studies	20% ± 4%	Explore
mast cell	10 studies	27% ± 6%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	25% ± 5%	Explore
dendritic cell	10 studies	30% ± 20%	Explore
gamma-delta T cell	10 studies	24% ± 14%	Explore
endothelial cell of lymphatic vessel	9 studies	32% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	21% ± 5%	Explore
capillary endothelial cell	9 studies	21% ± 3%	Explore
myofibroblast cell	9 studies	25% ± 6%	Explore
myeloid cell	9 studies	24% ± 11%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	20% ± 4%	Explore
connective tissue cell	8 studies	23% ± 8%	Explore
endothelial cell of vascular tree	8 studies	23% ± 5%	Explore
endothelial cell of artery	7 studies	22% ± 4%	Explore
epithelial cell	7 studies	38% ± 19%	Explore
ciliated cell	7 studies	28% ± 10%	Explore
memory B cell	7 studies	20% ± 2%	Explore
abnormal cell	7 studies	26% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	24% ± 9%	Explore
vein endothelial cell	6 studies	19% ± 4%	Explore
oligodendrocyte	6 studies	25% ± 11%	Explore
hematopoietic precursor cell	5 studies	35% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	25% ± 5%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	27% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	24% ± 5%	Explore
hematopoietic stem cell	5 studies	22% ± 4%	Explore
precursor B cell	5 studies	28% ± 9%	Explore
innate lymphoid cell	5 studies	21% ± 2%	Explore
astrocyte	5 studies	26% ± 10%	Explore
microglial cell	5 studies	28% ± 6%	Explore
oligodendrocyte precursor cell	5 studies	29% ± 12%	Explore
basal cell	5 studies	33% ± 12%	Explore
mucosal invariant T cell	5 studies	18% ± 2%	Explore
plasma cell	4 studies	31% ± 12%	Explore
leukocyte	4 studies	23% ± 7%	Explore
exhausted T cell	4 studies	31% ± 9%	Explore
kidney loop of Henle epithelial cell	4 studies	20% ± 2%	Explore
retinal ganglion cell	4 studies	47% ± 28%	Explore
T follicular helper cell	4 studies	21% ± 1%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	27% ± 5%	Explore
neuron	4 studies	33% ± 15%	Explore
glutamatergic neuron	4 studies	41% ± 14%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	23% ± 4%	Explore
plasmablast	3 studies	56% ± 3%	Explore
neutrophil	3 studies	21% ± 2%	Explore
mononuclear phagocyte	3 studies	35% ± 13%	Explore
glomerular endothelial cell	3 studies	19% ± 3%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	18% ± 0%	Explore
epithelial cell of proximal tubule	3 studies	18% ± 3%	Explore
neural crest cell	3 studies	19% ± 2%	Explore
lymphocyte	3 studies	27% ± 10%	Explore
immature B cell	3 studies	22% ± 6%	Explore
pro-B cell	3 studies	24% ± 6%	Explore
type II pneumocyte	3 studies	26% ± 12%	Explore
retina horizontal cell	3 studies	26% ± 12%	Explore
retinal cone cell	3 studies	36% ± 14%	Explore
retinal rod cell	3 studies	26% ± 9%	Explore
Mueller cell	3 studies	32% ± 6%	Explore
germinal center B cell	3 studies	23% ± 1%	Explore
intermediate monocyte	3 studies	35% ± 16%	Explore
granulocyte	3 studies	30% ± 9%	Explore
goblet cell	3 studies	28% ± 7%	Explore
group 3 innate lymphoid cell	3 studies	29% ± 14%	Explore
double negative thymocyte	3 studies	31% ± 15%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	13 studies	24% ± 8%	Explore
lung	8 studies	28% ± 8%	Explore
kidney	7 studies	18% ± 3%	Explore
brain	7 studies	33% ± 11%	Explore
eye	5 studies	26% ± 10%	Explore
intestine	4 studies	24% ± 13%	Explore
uterus	4 studies	25% ± 11%	Explore
lymph node	4 studies	21% ± 6%	Explore
liver	4 studies	28% ± 14%	Explore
bone marrow	3 studies	18% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	4517.60	2642 / 2642	100%	96.95	705 / 705
esophagus	100%	4179.99	1445 / 1445	100%	44.43	183 / 183
kidney	100%	3608.45	89 / 89	100%	58.00	901 / 901
liver	100%	1907.96	226 / 226	100%	40.79	406 / 406
lung	100%	3671.50	578 / 578	100%	53.49	1155 / 1155
ovary	100%	3962.43	180 / 180	100%	56.87	430 / 430
prostate	100%	3713.29	245 / 245	100%	58.01	502 / 502
skin	100%	4199.76	1809 / 1809	100%	87.59	472 / 472
stomach	100%	2944.90	359 / 359	100%	65.11	286 / 286
uterus	100%	4243.85	170 / 170	100%	67.03	459 / 459
thymus	100%	3537.15	653 / 653	100%	61.05	604 / 605
breast	100%	4135.02	459 / 459	100%	72.28	1116 / 1118
bladder	100%	4474.00	21 / 21	100%	64.08	502 / 504
adrenal gland	100%	4211.04	258 / 258	100%	56.56	229 / 230
intestine	100%	4112.78	966 / 966	99%	69.61	524 / 527
pancreas	98%	1670.19	322 / 328	100%	57.55	178 / 178
adipose	100%	4147.50	1204 / 1204	0%	0	0 / 0
blood vessel	100%	4891.53	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	75.69	80 / 80
lymph node	0%	0	0 / 0	100%	76.29	29 / 29
muscle	100%	4591.11	803 / 803	0%	0	0 / 0
spleen	100%	4146.89	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	57.41	45 / 45
ureter	0%	0	0 / 0	100%	25.26	1 / 1
peripheral blood	100%	7104.79	928 / 929	0%	0	0 / 0
heart	99%	3065.97	853 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0072711	Biological process	cellular response to hydroxyurea
GO_1902979	Biological process	mitotic DNA replication termination
GO_0006274	Biological process	DNA replication termination
GO_0097752	Biological process	regulation of DNA stability
GO_0005657	Cellular component	replication fork
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	RTF2
Protein name	Replication termination factor 2 (RTF2) (Replication termination factor 2 domain-containing protein 1) Replication termination factor 2 (Replication termination factor 2 domain-containing protein 1)
Synonyms	HSPC169 RTFDC1 HSPC164 AD-007 CDA05 C20orf43
Description	FUNCTION: Replication termination factor which is a component of the elongating replisome (Probable). Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion (Probable). Interacts with nascent DNA . .
Accessions	ENST00000023939.8 ENST00000449062.1 Q9BY42 A2A2L5 ENST00000357348.10 ENST00000395881.7 A0A0A0MQR2 A2A2L6

RTF2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review