PTBP3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	31 studies	28% ± 13%	Explore
endothelial cell	25 studies	27% ± 10%	Explore
classical monocyte	22 studies	26% ± 12%	Explore
natural killer cell	21 studies	23% ± 5%	Explore
B cell	19 studies	22% ± 5%	Explore
CD8-positive, alpha-beta T cell	19 studies	22% ± 5%	Explore
conventional dendritic cell	18 studies	25% ± 13%	Explore
non-classical monocyte	18 studies	28% ± 13%	Explore
CD4-positive, alpha-beta T cell	18 studies	21% ± 4%	Explore
regulatory T cell	18 studies	22% ± 4%	Explore
monocyte	17 studies	29% ± 12%	Explore
plasmacytoid dendritic cell	17 studies	34% ± 11%	Explore
naive B cell	16 studies	22% ± 5%	Explore
T cell	14 studies	25% ± 10%	Explore
dendritic cell	14 studies	39% ± 21%	Explore
ciliated cell	14 studies	34% ± 13%	Explore
gamma-delta T cell	13 studies	24% ± 8%	Explore
mast cell	12 studies	22% ± 7%	Explore
epithelial cell	12 studies	37% ± 21%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	24% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	22% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	21% ± 3%	Explore
memory B cell	11 studies	22% ± 5%	Explore
mucosal invariant T cell	11 studies	23% ± 4%	Explore
myeloid cell	11 studies	33% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	26% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	21% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	22% ± 3%	Explore
microglial cell	10 studies	37% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	9 studies	20% ± 2%	Explore
mature NK T cell	9 studies	23% ± 3%	Explore
endothelial cell of lymphatic vessel	8 studies	27% ± 9%	Explore
basal cell	8 studies	36% ± 20%	Explore
pericyte	7 studies	20% ± 6%	Explore
leukocyte	6 studies	29% ± 8%	Explore
interneuron	6 studies	33% ± 15%	Explore
lymphocyte	6 studies	30% ± 12%	Explore
neutrophil	6 studies	26% ± 11%	Explore
club cell	6 studies	28% ± 12%	Explore
fibroblast	6 studies	27% ± 5%	Explore
type II pneumocyte	6 studies	23% ± 6%	Explore
GABAergic neuron	6 studies	34% ± 14%	Explore
type I pneumocyte	5 studies	25% ± 7%	Explore
hematopoietic precursor cell	5 studies	38% ± 20%	Explore
respiratory goblet cell	5 studies	24% ± 6%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	24% ± 2%	Explore
mononuclear phagocyte	5 studies	25% ± 8%	Explore
podocyte	5 studies	39% ± 13%	Explore
neuron	5 studies	37% ± 18%	Explore
oligodendrocyte precursor cell	5 studies	28% ± 11%	Explore
brush cell	5 studies	29% ± 10%	Explore
capillary endothelial cell	5 studies	20% ± 4%	Explore
secretory cell	5 studies	26% ± 5%	Explore
abnormal cell	5 studies	25% ± 14%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	22% ± 5%	Explore
glutamatergic neuron	5 studies	49% ± 20%	Explore
goblet cell	5 studies	36% ± 24%	Explore
alveolar macrophage	5 studies	36% ± 12%	Explore
smooth muscle cell	5 studies	19% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	22% ± 4%	Explore
squamous epithelial cell	4 studies	39% ± 23%	Explore
exhausted T cell	4 studies	24% ± 6%	Explore
precursor B cell	4 studies	22% ± 4%	Explore
pro-B cell	4 studies	25% ± 5%	Explore
vein endothelial cell	4 studies	28% ± 11%	Explore
T follicular helper cell	4 studies	21% ± 4%	Explore
innate lymphoid cell	4 studies	20% ± 3%	Explore
transit amplifying cell	4 studies	36% ± 32%	Explore
renal principal cell	4 studies	44% ± 8%	Explore
hillock cell	3 studies	21% ± 6%	Explore
progenitor cell	3 studies	18% ± 2%	Explore
endothelial cell of artery	3 studies	21% ± 3%	Explore
tissue-resident macrophage	3 studies	24% ± 7%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	24% ± 1%	Explore
endothelial cell of vascular tree	3 studies	27% ± 14%	Explore
hematopoietic stem cell	3 studies	28% ± 9%	Explore
enteroendocrine cell	3 studies	25% ± 5%	Explore
group 3 innate lymphoid cell	3 studies	26% ± 8%	Explore
astrocyte	3 studies	29% ± 13%	Explore
T-helper 1 cell	3 studies	20% ± 5%	Explore
immature B cell	3 studies	22% ± 4%	Explore
double negative thymocyte	3 studies	29% ± 5%	Explore
oligodendrocyte	3 studies	22% ± 9%	Explore
renal alpha-intercalated cell	3 studies	44% ± 5%	Explore
mural cell	3 studies	28% ± 14%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	13 studies	25% ± 8%	Explore
lung	10 studies	29% ± 13%	Explore
brain	6 studies	39% ± 15%	Explore
kidney	6 studies	22% ± 5%	Explore
bone marrow	4 studies	28% ± 10%	Explore
intestine	3 studies	18% ± 1%	Explore
adipose	3 studies	20% ± 1%	Explore
liver	3 studies	33% ± 15%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	5756.74	578 / 578	100%	73.51	1155 / 1155
bladder	100%	3950.00	21 / 21	100%	74.77	503 / 504
esophagus	100%	5066.11	1441 / 1445	100%	126.22	183 / 183
breast	100%	4740.18	459 / 459	100%	76.89	1114 / 1118
stomach	100%	3223.70	358 / 359	100%	94.48	285 / 286
intestine	100%	3973.33	965 / 966	99%	90.48	524 / 527
uterus	100%	3303.24	170 / 170	99%	68.35	454 / 459
prostate	100%	3253.11	245 / 245	97%	32.65	489 / 502
thymus	100%	3526.47	652 / 653	97%	32.03	588 / 605
pancreas	98%	2356.72	321 / 328	98%	66.65	175 / 178
kidney	100%	5596.22	89 / 89	96%	42.04	866 / 901
ovary	100%	2836.93	180 / 180	96%	30.78	412 / 430
skin	100%	6974.31	1809 / 1809	88%	29.62	417 / 472
adrenal gland	100%	2475.20	258 / 258	76%	17.32	174 / 230
liver	96%	1668.35	218 / 226	72%	18.77	294 / 406
brain	85%	1433.88	2256 / 2642	62%	11.08	437 / 705
adipose	100%	4760.51	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	50.15	29 / 29
spleen	100%	4633.07	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	97.19	45 / 45
ureter	0%	0	0 / 0	100%	41.43	1 / 1
blood vessel	100%	3002.53	1332 / 1335	0%	0	0 / 0
peripheral blood	99%	7983.03	922 / 929	0%	0	0 / 0
heart	88%	1593.07	755 / 861	0%	0	0 / 0
muscle	69%	1033.59	551 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	55%	11.14	44 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0043484	Biological process	regulation of RNA splicing
GO_0033119	Biological process	negative regulation of RNA splicing
GO_0008380	Biological process	RNA splicing
GO_0006397	Biological process	mRNA processing
GO_0045595	Biological process	regulation of cell differentiation
GO_0043249	Biological process	erythrocyte maturation
GO_0009653	Biological process	anatomical structure morphogenesis
GO_0005634	Cellular component	nucleus
GO_0003729	Molecular function	mRNA binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	PTBP3
Protein name	Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1) Polypyrimidine tract binding protein 3
Synonyms	ROD1
Description	FUNCTION: RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U). .
Accessions	B1ALY4 ENST00000374257.6 [O95758-6] ENST00000334318.10 [O95758-5] ENST00000374255.6 [O95758-3] ENST00000450374.1 ENST00000458258.5 [O95758-4] ENST00000210227.4 ENST00000343327.6 [O95758-7] O95758 X6R242

PTBP3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review