NDUFV1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	26 studies	31% ± 11%	Explore
CD8-positive, alpha-beta T cell	22 studies	30% ± 11%	Explore
fibroblast	19 studies	26% ± 10%	Explore
pericyte	19 studies	25% ± 8%	Explore
smooth muscle cell	18 studies	24% ± 10%	Explore
conventional dendritic cell	17 studies	27% ± 15%	Explore
CD4-positive, alpha-beta T cell	17 studies	29% ± 12%	Explore
endothelial cell	17 studies	26% ± 10%	Explore
B cell	16 studies	26% ± 7%	Explore
basal cell	16 studies	28% ± 14%	Explore
macrophage	15 studies	24% ± 7%	Explore
regulatory T cell	15 studies	28% ± 8%	Explore
epithelial cell	14 studies	35% ± 19%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	32% ± 9%	Explore
classical monocyte	13 studies	23% ± 8%	Explore
T cell	12 studies	26% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	34% ± 7%	Explore
naive B cell	12 studies	23% ± 4%	Explore
memory B cell	11 studies	24% ± 7%	Explore
plasma cell	11 studies	35% ± 12%	Explore
plasmacytoid dendritic cell	11 studies	29% ± 9%	Explore
gamma-delta T cell	11 studies	31% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	28% ± 9%	Explore
ciliated cell	10 studies	30% ± 10%	Explore
mature NK T cell	10 studies	31% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	10 studies	24% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	29% ± 5%	Explore
myofibroblast cell	10 studies	29% ± 9%	Explore
connective tissue cell	10 studies	26% ± 9%	Explore
plasmablast	9 studies	42% ± 23%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	28% ± 7%	Explore
non-classical monocyte	9 studies	26% ± 8%	Explore
mucosal invariant T cell	9 studies	28% ± 4%	Explore
progenitor cell	8 studies	27% ± 7%	Explore
abnormal cell	8 studies	30% ± 12%	Explore
transit amplifying cell	7 studies	32% ± 12%	Explore
dendritic cell	7 studies	40% ± 17%	Explore
astrocyte	7 studies	30% ± 10%	Explore
monocyte	7 studies	23% ± 8%	Explore
club cell	6 studies	26% ± 7%	Explore
secretory cell	6 studies	29% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	26% ± 5%	Explore
epithelial cell of proximal tubule	6 studies	39% ± 6%	Explore
renal alpha-intercalated cell	6 studies	47% ± 13%	Explore
goblet cell	6 studies	27% ± 7%	Explore
neuron	6 studies	37% ± 15%	Explore
retinal rod cell	6 studies	23% ± 4%	Explore
endothelial cell of vascular tree	6 studies	19% ± 2%	Explore
oligodendrocyte precursor cell	6 studies	31% ± 8%	Explore
hematopoietic precursor cell	5 studies	36% ± 15%	Explore
kidney loop of Henle epithelial cell	5 studies	43% ± 8%	Explore
enterocyte	5 studies	26% ± 1%	Explore
glutamatergic neuron	5 studies	41% ± 23%	Explore
retinal ganglion cell	5 studies	64% ± 28%	Explore
erythroblast	5 studies	31% ± 16%	Explore
precursor B cell	5 studies	28% ± 7%	Explore
endothelial cell of lymphatic vessel	5 studies	28% ± 8%	Explore
cardiac muscle cell	5 studies	26% ± 7%	Explore
T follicular helper cell	5 studies	23% ± 4%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	38% ± 9%	Explore
GABAergic neuron	5 studies	34% ± 18%	Explore
oligodendrocyte	5 studies	35% ± 12%	Explore
respiratory goblet cell	4 studies	36% ± 16%	Explore
exhausted T cell	4 studies	33% ± 4%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	38% ± 13%	Explore
capillary endothelial cell	4 studies	23% ± 7%	Explore
intestinal crypt stem cell	4 studies	29% ± 9%	Explore
leukocyte	4 studies	23% ± 7%	Explore
vein endothelial cell	4 studies	23% ± 8%	Explore
hematopoietic stem cell	4 studies	28% ± 8%	Explore
pro-B cell	4 studies	26% ± 5%	Explore
myeloid cell	4 studies	25% ± 8%	Explore
mesothelial cell	4 studies	36% ± 15%	Explore
type I pneumocyte	4 studies	27% ± 6%	Explore
amacrine cell	4 studies	29% ± 11%	Explore
retina horizontal cell	4 studies	29% ± 10%	Explore
retinal cone cell	4 studies	35% ± 12%	Explore
Mueller cell	4 studies	20% ± 1%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	32% ± 1%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	30% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	24% ± 5%	Explore
ionocyte	3 studies	33% ± 6%	Explore
mononuclear phagocyte	3 studies	29% ± 17%	Explore
endothelial cell of artery	3 studies	17% ± 0%	Explore
neural crest cell	3 studies	27% ± 3%	Explore
retinal bipolar neuron	3 studies	31% ± 12%	Explore
common myeloid progenitor	3 studies	37% ± 16%	Explore
immature B cell	3 studies	30% ± 6%	Explore
type II pneumocyte	3 studies	30% ± 11%	Explore
serous secreting cell	3 studies	23% ± 5%	Explore
OFF-bipolar cell	3 studies	43% ± 28%	Explore
ON-bipolar cell	3 studies	48% ± 29%	Explore
rod bipolar cell	3 studies	35% ± 3%	Explore
intermediate monocyte	3 studies	30% ± 14%	Explore
adipocyte	3 studies	28% ± 14%	Explore
microglial cell	3 studies	20% ± 6%	Explore
granulocyte monocyte progenitor cell	3 studies	35% ± 14%	Explore
enteroendocrine cell	3 studies	32% ± 10%	Explore
group 3 innate lymphoid cell	3 studies	35% ± 10%	Explore
interneuron	3 studies	33% ± 14%	Explore
double negative thymocyte	3 studies	41% ± 13%	Explore
hepatocyte	3 studies	32% ± 19%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	26% ± 7%	Explore
lung	10 studies	26% ± 7%	Explore
kidney	8 studies	27% ± 5%	Explore
intestine	8 studies	25% ± 10%	Explore
eye	8 studies	25% ± 7%	Explore
brain	6 studies	37% ± 16%	Explore
lymph node	5 studies	25% ± 10%	Explore
liver	4 studies	28% ± 18%	Explore
bone marrow	3 studies	20% ± 5%	Explore
heart	3 studies	17% ± 2%	Explore
uterus	3 studies	28% ± 12%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	7773.58	1445 / 1445	100%	66.51	183 / 183
liver	100%	7733.36	226 / 226	100%	108.40	406 / 406
ovary	100%	8346.20	180 / 180	100%	97.99	430 / 430
pancreas	100%	5314.81	328 / 328	100%	79.88	178 / 178
skin	100%	8128.03	1809 / 1809	100%	115.47	472 / 472
uterus	100%	7843.23	170 / 170	100%	102.49	459 / 459
brain	100%	8745.44	2635 / 2642	100%	130.32	705 / 705
thymus	100%	9674.95	653 / 653	100%	91.44	603 / 605
intestine	100%	9475.91	966 / 966	100%	110.80	525 / 527
kidney	100%	12686.67	89 / 89	100%	100.08	897 / 901
prostate	100%	7184.01	245 / 245	99%	85.28	499 / 502
stomach	100%	7894.18	359 / 359	99%	91.19	284 / 286
lung	100%	6476.99	576 / 578	99%	81.30	1149 / 1155
bladder	100%	7188.43	21 / 21	99%	103.52	498 / 504
adrenal gland	100%	9555.42	258 / 258	99%	77.58	227 / 230
breast	100%	7660.26	459 / 459	98%	74.80	1101 / 1118
adipose	100%	7321.67	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	164.90	80 / 80
lymph node	0%	0	0 / 0	100%	151.99	29 / 29
muscle	100%	16385.64	803 / 803	0%	0	0 / 0
spleen	100%	8574.03	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	111.99	45 / 45
ureter	0%	0	0 / 0	100%	75.96	1 / 1
blood vessel	100%	6276.45	1334 / 1335	0%	0	0 / 0
heart	99%	17120.09	850 / 861	0%	0	0 / 0
peripheral blood	87%	5143.58	811 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0042775	Biological process	mitochondrial ATP synthesis coupled electron transport
GO_0009060	Biological process	aerobic respiration
GO_0006120	Biological process	mitochondrial electron transport, NADH to ubiquinone
GO_0042776	Biological process	proton motive force-driven mitochondrial ATP synthesis
GO_0055085	Biological process	transmembrane transport
GO_0045271	Cellular component	respiratory chain complex I
GO_0005829	Cellular component	cytosol
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0005739	Cellular component	mitochondrion
GO_0051287	Molecular function	NAD binding
GO_0010181	Molecular function	FMN binding
GO_0008137	Molecular function	NADH dehydrogenase (ubiquinone) activity
GO_0005515	Molecular function	protein binding
GO_0051539	Molecular function	4 iron, 4 sulfur cluster binding
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	NDUFV1
Protein name	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC 7.1.1.2) NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (NDUFV1) (EC 7.1.1.2) (Complex I-51kD) (CI-51kD) (NADH dehydrogenase flavoprotein 1) (NADH-ubiquinone oxidoreductase 51 kDa subunit) NADH:ubiquinone oxidoreductase core subunit V1 (cDNA FLJ57949, highly similar to NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial) (cDNA, FLJ79021, highly similar to NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial) NADH:ubiquinone oxidoreductase core subunit V1
Synonyms	hCG_21057 UQOR1
Description	FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor . Part of the peripheral arm of the enzyme, where the electrons from NADH are accepted by flavin mononucleotide (FMN) and then passed along a chain of iron-sulfur clusters by electron tunnelling to the final acceptor ubiquinone . Contains FMN, which is the initial electron acceptor as well as one iron-sulfur cluster . . FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I. .
Accessions	ENST00000529867.5 E9PMX3 E9PPD6 ENST00000528314.1 ENST00000533919.5 ENST00000529927.5 [P49821-2] B4DE93 E9PPR0 ENST00000530638.1 E9PPS5 ENST00000527355.5 E9PPE0 ENST00000322776.11 [P49821-1] E9PLC6 H0YE81 ENST00000532303.5 ENST00000415352.6 P49821 G3V0I5 ENST00000532244.5 ENST00000647561.1 [P49821-1] ENST00000533075.5 E9PJL9 E9PQP1 ENST00000528328.1 ENST00000532343.5 H0YD04 ENST00000530103.5

NDUFV1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review