Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| lung | 14 studies | 31% ± 14% | |
| peripheral blood | 12 studies | 26% ± 8% | |
| intestine | 10 studies | 29% ± 13% | |
| kidney | 9 studies | 29% ± 7% | |
| brain | 7 studies | 24% ± 5% | |
| eye | 5 studies | 30% ± 13% | |
| uterus | 5 studies | 27% ± 15% | |
| lymph node | 5 studies | 24% ± 11% | |
| pancreas | 3 studies | 47% ± 9% | |
| bone marrow | 3 studies | 18% ± 1% | |
| ovary | 3 studies | 19% ± 2% | |
| adrenal gland | 3 studies | 19% ± 2% | |
| breast | 3 studies | 21% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2816.74 | 1445 / 1445 | 100% | 44.57 | 183 / 183 |
| liver | 100% | 2122.32 | 226 / 226 | 100% | 35.01 | 406 / 406 |
| ovary | 100% | 2202.38 | 180 / 180 | 100% | 66.65 | 430 / 430 |
| uterus | 100% | 1789.91 | 170 / 170 | 100% | 55.97 | 459 / 459 |
| brain | 100% | 4358.44 | 2641 / 2642 | 100% | 50.81 | 705 / 705 |
| kidney | 100% | 4161.83 | 89 / 89 | 100% | 46.25 | 899 / 901 |
| thymus | 100% | 2650.37 | 652 / 653 | 100% | 40.77 | 604 / 605 |
| bladder | 100% | 2769.81 | 21 / 21 | 100% | 42.57 | 502 / 504 |
| breast | 100% | 2708.28 | 459 / 459 | 100% | 45.59 | 1113 / 1118 |
| prostate | 100% | 2033.73 | 244 / 245 | 100% | 38.32 | 501 / 502 |
| adrenal gland | 100% | 4494.58 | 258 / 258 | 99% | 38.35 | 228 / 230 |
| stomach | 100% | 2799.89 | 359 / 359 | 99% | 41.37 | 283 / 286 |
| intestine | 100% | 3496.42 | 966 / 966 | 99% | 41.83 | 521 / 527 |
| lung | 99% | 2161.14 | 570 / 578 | 100% | 56.10 | 1155 / 1155 |
| pancreas | 98% | 1591.24 | 323 / 328 | 100% | 32.88 | 178 / 178 |
| skin | 100% | 2454.71 | 1805 / 1809 | 99% | 39.72 | 465 / 472 |
| adipose | 100% | 2938.06 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 53.49 | 29 / 29 |
| muscle | 100% | 5797.45 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2649.35 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 68.30 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 21.14 | 1 / 1 |
| blood vessel | 100% | 2018.46 | 1330 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 6233.07 | 851 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 98% | 32.92 | 78 / 80 |
| peripheral blood | 67% | 1419.45 | 620 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0009060 | Biological process | aerobic respiration |
| GO_0006120 | Biological process | mitochondrial electron transport, NADH to ubiquinone |
| GO_0042776 | Biological process | proton motive force-driven mitochondrial ATP synthesis |
| GO_0055085 | Biological process | transmembrane transport |
| GO_0032981 | Biological process | mitochondrial respiratory chain complex I assembly |
| GO_0045271 | Cellular component | respiratory chain complex I |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0008137 | Molecular function | NADH dehydrogenase (ubiquinone) activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | NDUFB5 |
| Protein name | NADH:ubiquinone oxidoreductase subunit B5 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (Complex I-SGDH) (NADH-ubiquinone oxidoreductase SGDH subunit) NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (Complex I-SGDH) (CI-SGDH) (NADH-ubiquinone oxidoreductase SGDH subunit) |
| Synonyms | hCG_1787208 |
| Description | FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . |
| Accessions | E7EWP0 ENST00000472629.5 ENST00000482604.5 ENST00000611971.4 H7C568 ENST00000493866.5 [O43674-2] H7C5C1 H0Y886 ENST00000259037.8 [O43674-1] ENST00000359944.10 ENST00000471112.1 ENST00000480374.1 F8WDD2 A0A087WYD0 O43674 ENST00000468210.5 Q05D62 F8WDZ2 |