H1-2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030261Biological processchromosome condensation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0045910Biological processnegative regulation of DNA recombination
GO_0006334Biological processnucleosome assembly
GO_0000791Cellular componenteuchromatin
GO_0000786Cellular componentnucleosome
GO_0005634Cellular componentnucleus
GO_0003690Molecular functiondouble-stranded DNA binding
GO_0030527Molecular functionstructural constituent of chromatin
GO_0031490Molecular functionchromatin DNA binding
GO_0031492Molecular functionnucleosomal DNA binding
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameH1-2
Protein nameHistone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1)
SynonymsHIST1H1C
H1F2
DescriptionFUNCTION: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). .

AccessionsENST00000343677.4
P16403