FABP5 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	29 studies	48% ± 20%	Explore
conventional dendritic cell	28 studies	34% ± 11%	Explore
endothelial cell	24 studies	50% ± 22%	Explore
endothelial cell of lymphatic vessel	24 studies	71% ± 15%	Explore
pericyte	22 studies	36% ± 22%	Explore
dendritic cell	18 studies	40% ± 18%	Explore
epithelial cell	18 studies	44% ± 20%	Explore
fibroblast	18 studies	37% ± 17%	Explore
basal cell	17 studies	51% ± 21%	Explore
CD8-positive, alpha-beta T cell	17 studies	36% ± 21%	Explore
T cell	16 studies	32% ± 14%	Explore
plasmacytoid dendritic cell	16 studies	29% ± 9%	Explore
B cell	14 studies	24% ± 10%	Explore
monocyte	14 studies	30% ± 11%	Explore
vein endothelial cell	14 studies	51% ± 20%	Explore
connective tissue cell	13 studies	39% ± 11%	Explore
smooth muscle cell	12 studies	28% ± 12%	Explore
myeloid cell	12 studies	43% ± 18%	Explore
classical monocyte	11 studies	26% ± 11%	Explore
endothelial cell of artery	10 studies	50% ± 22%	Explore
natural killer cell	10 studies	28% ± 16%	Explore
capillary endothelial cell	10 studies	64% ± 24%	Explore
non-classical monocyte	9 studies	25% ± 9%	Explore
progenitor cell	9 studies	48% ± 17%	Explore
regulatory T cell	9 studies	26% ± 16%	Explore
type II pneumocyte	8 studies	71% ± 26%	Explore
club cell	8 studies	54% ± 19%	Explore
memory B cell	8 studies	21% ± 14%	Explore
alveolar macrophage	7 studies	67% ± 29%	Explore
plasmablast	7 studies	54% ± 17%	Explore
mononuclear phagocyte	7 studies	33% ± 10%	Explore
transit amplifying cell	7 studies	46% ± 16%	Explore
precursor B cell	7 studies	35% ± 12%	Explore
plasma cell	6 studies	37% ± 22%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	25% ± 10%	Explore
secretory cell	6 studies	50% ± 12%	Explore
myofibroblast cell	6 studies	39% ± 15%	Explore
goblet cell	6 studies	26% ± 6%	Explore
neuron	6 studies	49% ± 17%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	40% ± 17%	Explore
hematopoietic precursor cell	5 studies	52% ± 24%	Explore
respiratory goblet cell	5 studies	49% ± 15%	Explore
monocyte-derived dendritic cell	5 studies	46% ± 14%	Explore
abnormal cell	5 studies	38% ± 16%	Explore
leukocyte	5 studies	36% ± 9%	Explore
mesothelial cell	5 studies	34% ± 13%	Explore
hematopoietic stem cell	5 studies	37% ± 14%	Explore
pro-B cell	5 studies	33% ± 12%	Explore
ciliated cell	5 studies	37% ± 15%	Explore
endothelial cell of vascular tree	5 studies	33% ± 14%	Explore
gamma-delta T cell	5 studies	29% ± 22%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	19% ± 2%	Explore
pancreatic A cell	4 studies	63% ± 6%	Explore
exhausted T cell	4 studies	45% ± 9%	Explore
enteroendocrine cell	4 studies	48% ± 14%	Explore
intestinal crypt stem cell	4 studies	33% ± 11%	Explore
erythroblast	4 studies	32% ± 10%	Explore
T follicular helper cell	4 studies	27% ± 9%	Explore
oligodendrocyte precursor cell	4 studies	27% ± 11%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	52% ± 20%	Explore
keratinocyte	4 studies	45% ± 19%	Explore
CD4-positive, alpha-beta T cell	4 studies	63% ± 13%	Explore
type I pneumocyte	3 studies	38% ± 4%	Explore
deuterosomal cell	3 studies	29% ± 6%	Explore
precursor cell	3 studies	63% ± 4%	Explore
naive B cell	3 studies	20% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	23% ± 10%	Explore
neural crest cell	3 studies	57% ± 5%	Explore
common myeloid progenitor	3 studies	46% ± 5%	Explore
lymphocyte	3 studies	51% ± 20%	Explore
Mueller cell	3 studies	43% ± 8%	Explore
astrocyte	3 studies	22% ± 2%	Explore
double negative thymocyte	3 studies	54% ± 27%	Explore
germinal center B cell	3 studies	33% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	24% ± 4%	Explore
GABAergic neuron	3 studies	22% ± 5%	Explore
glutamatergic neuron	3 studies	22% ± 2%	Explore
granulocyte monocyte progenitor cell	3 studies	56% ± 28%	Explore
immature B cell	3 studies	34% ± 19%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	35% ± 11%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	36% ± 16%	Explore
intestine	10 studies	32% ± 7%	Explore
eye	6 studies	22% ± 6%	Explore
kidney	5 studies	25% ± 8%	Explore
lymph node	5 studies	26% ± 10%	Explore
pancreas	4 studies	29% ± 8%	Explore
peripheral blood	4 studies	29% ± 13%	Explore
heart	4 studies	22% ± 7%	Explore
brain	4 studies	25% ± 8%	Explore
esophagus	4 studies	56% ± 24%	Explore
liver	4 studies	23% ± 5%	Explore
uterus	3 studies	32% ± 7%	Explore
thymus	3 studies	52% ± 26%	Explore
breast	3 studies	25% ± 9%	Explore
bone marrow	3 studies	25% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	91%	19351.18	1310 / 1445	97%	466.33	178 / 183
intestine	84%	1714.54	811 / 966	92%	46.69	485 / 527
stomach	85%	1542.79	306 / 359	89%	39.08	255 / 286
bladder	76%	3082.86	16 / 21	87%	105.67	437 / 504
skin	85%	6449.04	1544 / 1809	77%	38.54	364 / 472
lung	81%	1977.22	469 / 578	68%	66.90	787 / 1155
breast	92%	3415.01	420 / 459	33%	12.95	367 / 1118
uterus	33%	1154.13	56 / 170	86%	374.66	396 / 459
brain	81%	1338.60	2145 / 2642	34%	34.52	242 / 705
lymph node	0%	0	0 / 0	100%	48.82	29 / 29
ureter	0%	0	0 / 0	100%	249.11	1 / 1
adipose	100%	4846.93	1200 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	270.17	44 / 45
heart	92%	2072.44	790 / 861	0%	0	0 / 0
spleen	88%	1832.06	211 / 241	0%	0	0 / 0
thymus	64%	1023.76	420 / 653	19%	7.87	114 / 605
ovary	1%	9.24	2 / 180	78%	21.98	337 / 430
pancreas	17%	191.77	57 / 328	55%	20.21	98 / 178
prostate	10%	102.14	24 / 245	48%	38.65	242 / 502
muscle	36%	374.66	291 / 803	0%	0	0 / 0
kidney	8%	97.03	7 / 89	18%	3.87	162 / 901
eye	0%	0	0 / 0	25%	5.78	20 / 80
blood vessel	24%	392.89	316 / 1335	0%	0	0 / 0
peripheral blood	20%	559.76	182 / 929	0%	0	0 / 0
adrenal gland	3%	37.87	7 / 258	13%	2.66	31 / 230
liver	1%	25.32	3 / 226	10%	2.97	39 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0008544	Biological process	epidermis development
GO_0099178	Biological process	regulation of retrograde trans-synaptic signaling by endocanabinoid
GO_0015909	Biological process	long-chain fatty acid transport
GO_0035360	Biological process	positive regulation of peroxisome proliferator activated receptor signaling pathway
GO_0006656	Biological process	phosphatidylcholine biosynthetic process
GO_0051930	Biological process	regulation of sensory perception of pain
GO_0015908	Biological process	fatty acid transport
GO_0120162	Biological process	positive regulation of cold-induced thermogenesis
GO_0010829	Biological process	negative regulation of glucose transmembrane transport
GO_0031392	Biological process	regulation of prostaglandin biosynthetic process
GO_0006629	Biological process	lipid metabolic process
GO_1990379	Biological process	lipid transport across blood-brain barrier
GO_0006006	Biological process	glucose metabolic process
GO_0042593	Biological process	glucose homeostasis
GO_0035578	Cellular component	azurophil granule lumen
GO_0030667	Cellular component	secretory granule membrane
GO_0005576	Cellular component	extracellular region
GO_0005886	Cellular component	plasma membrane
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0045202	Cellular component	synapse
GO_0014069	Cellular component	postsynaptic density
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005324	Molecular function	long-chain fatty acid transmembrane transporter activity
GO_0008289	Molecular function	lipid binding
GO_0042802	Molecular function	identical protein binding
GO_0005504	Molecular function	fatty acid binding
GO_0001972	Molecular function	retinoic acid binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	FABP5
Protein name	Fatty acid-binding protein 5 (Epidermal-type fatty acid-binding protein) (E-FABP) (Fatty acid-binding protein, epidermal) (Psoriasis-associated fatty acid-binding protein homolog) (PA-FABP) Fatty acid-binding protein 5 (Epidermal-type fatty acid-binding protein) (Fatty acid-binding protein, epidermal)
Synonyms
Description	FUNCTION: Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors . Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation (By similarity). May be involved in keratinocyte differentiation . .
Accessions	I6L8B7 Q01469 ENST00000396359.1 E7DVW5 ENST00000297258.11

FABP5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review