ETFB | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	21 studies	25% ± 11%	Explore
macrophage	18 studies	25% ± 10%	Explore
fibroblast	17 studies	25% ± 12%	Explore
classical monocyte	17 studies	26% ± 12%	Explore
B cell	16 studies	22% ± 6%	Explore
CD4-positive, alpha-beta T cell	16 studies	27% ± 10%	Explore
T cell	15 studies	21% ± 5%	Explore
epithelial cell	14 studies	40% ± 21%	Explore
regulatory T cell	14 studies	23% ± 7%	Explore
ciliated cell	14 studies	36% ± 15%	Explore
basal cell	13 studies	31% ± 16%	Explore
endothelial cell of lymphatic vessel	12 studies	23% ± 8%	Explore
conventional dendritic cell	12 studies	27% ± 15%	Explore
CD8-positive, alpha-beta T cell	12 studies	30% ± 10%	Explore
natural killer cell	11 studies	24% ± 7%	Explore
smooth muscle cell	11 studies	23% ± 5%	Explore
non-classical monocyte	11 studies	32% ± 13%	Explore
pericyte	11 studies	23% ± 5%	Explore
mast cell	10 studies	19% ± 5%	Explore
connective tissue cell	10 studies	22% ± 5%	Explore
monocyte	10 studies	25% ± 10%	Explore
plasmacytoid dendritic cell	9 studies	24% ± 7%	Explore
plasma cell	8 studies	29% ± 13%	Explore
enterocyte	8 studies	43% ± 21%	Explore
goblet cell	8 studies	40% ± 14%	Explore
memory B cell	8 studies	18% ± 2%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	19% ± 5%	Explore
mature NK T cell	7 studies	18% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	28% ± 13%	Explore
epithelial cell of proximal tubule	7 studies	56% ± 15%	Explore
progenitor cell	7 studies	41% ± 17%	Explore
dendritic cell	7 studies	42% ± 25%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	25% ± 8%	Explore
renal alpha-intercalated cell	6 studies	42% ± 12%	Explore
gamma-delta T cell	6 studies	28% ± 20%	Explore
transit amplifying cell	6 studies	40% ± 22%	Explore
abnormal cell	6 studies	34% ± 14%	Explore
myeloid cell	6 studies	30% ± 14%	Explore
astrocyte	6 studies	26% ± 13%	Explore
T follicular helper cell	6 studies	19% ± 4%	Explore
secretory cell	6 studies	27% ± 17%	Explore
hematopoietic precursor cell	5 studies	40% ± 20%	Explore
plasmablast	5 studies	48% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	24% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	22% ± 5%	Explore
kidney loop of Henle epithelial cell	5 studies	39% ± 7%	Explore
enteroendocrine cell	5 studies	41% ± 18%	Explore
vein endothelial cell	5 studies	18% ± 3%	Explore
club cell	5 studies	24% ± 9%	Explore
type II pneumocyte	5 studies	32% ± 17%	Explore
neuron	5 studies	40% ± 18%	Explore
hepatocyte	5 studies	50% ± 31%	Explore
endothelial cell of vascular tree	5 studies	19% ± 4%	Explore
type I pneumocyte	4 studies	31% ± 11%	Explore
myofibroblast cell	4 studies	27% ± 6%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	41% ± 7%	Explore
capillary endothelial cell	4 studies	19% ± 2%	Explore
oligodendrocyte	4 studies	25% ± 8%	Explore
endothelial cell of artery	4 studies	20% ± 2%	Explore
intestinal crypt stem cell	4 studies	47% ± 15%	Explore
retinal ganglion cell	4 studies	54% ± 25%	Explore
erythroblast	4 studies	35% ± 18%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	29% ± 13%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	27% ± 9%	Explore
hematopoietic stem cell	4 studies	22% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	31% ± 11%	Explore
T-helper 17 cell	4 studies	24% ± 12%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	26% ± 13%	Explore
pancreatic A cell	3 studies	40% ± 8%	Explore
mononuclear phagocyte	3 studies	34% ± 13%	Explore
exhausted T cell	3 studies	39% ± 12%	Explore
leukocyte	3 studies	29% ± 11%	Explore
naive B cell	3 studies	18% ± 2%	Explore
retinal bipolar neuron	3 studies	38% ± 16%	Explore
common myeloid progenitor	3 studies	33% ± 18%	Explore
lymphocyte	3 studies	29% ± 8%	Explore
brush cell	3 studies	24% ± 7%	Explore
amacrine cell	3 studies	41% ± 20%	Explore
retina horizontal cell	3 studies	42% ± 19%	Explore
retinal cone cell	3 studies	47% ± 9%	Explore
retinal rod cell	3 studies	24% ± 5%	Explore
intraepithelial lymphocyte	3 studies	24% ± 5%	Explore
Mueller cell	3 studies	26% ± 7%	Explore
germinal center B cell	3 studies	21% ± 1%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	21% ± 4%	Explore
glutamatergic neuron	3 studies	26% ± 5%	Explore
granulocyte monocyte progenitor cell	3 studies	38% ± 23%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	36% ± 21%	Explore
glial cell	3 studies	26% ± 13%	Explore
erythrocyte	3 studies	35% ± 17%	Explore
mucosal invariant T cell	3 studies	16% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	11 studies	27% ± 13%	Explore
peripheral blood	10 studies	25% ± 9%	Explore
intestine	9 studies	30% ± 14%	Explore
liver	8 studies	29% ± 17%	Explore
kidney	7 studies	31% ± 12%	Explore
eye	7 studies	25% ± 11%	Explore
bone marrow	4 studies	18% ± 2%	Explore
uterus	4 studies	29% ± 14%	Explore
lymph node	4 studies	16% ± 0%	Explore
brain	4 studies	21% ± 4%	Explore
pancreas	3 studies	31% ± 10%	Explore
placenta	3 studies	28% ± 12%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	4782.84	258 / 258	100%	14.75	230 / 230
liver	100%	7454.87	226 / 226	100%	42.77	406 / 406
kidney	100%	3438.02	89 / 89	100%	11.19	898 / 901
brain	100%	3059.65	2638 / 2642	100%	8.91	703 / 705
thymus	100%	2216.66	652 / 653	99%	13.03	601 / 605
intestine	100%	2604.76	966 / 966	99%	13.89	520 / 527
stomach	100%	2012.75	359 / 359	99%	12.09	282 / 286
prostate	99%	1695.31	243 / 245	99%	12.21	497 / 502
esophagus	100%	2977.35	1445 / 1445	98%	9.87	179 / 183
uterus	99%	1374.92	169 / 170	98%	12.79	449 / 459
bladder	100%	1868.10	21 / 21	97%	13.15	487 / 504
pancreas	98%	1169.32	321 / 328	98%	11.64	174 / 178
skin	100%	2379.22	1804 / 1809	96%	10.12	452 / 472
lung	98%	1541.20	568 / 578	95%	9.35	1096 / 1155
ovary	99%	1554.69	179 / 180	84%	4.56	362 / 430
breast	100%	3228.01	459 / 459	76%	5.42	853 / 1118
adipose	100%	3420.77	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	16.94	80 / 80
lymph node	0%	0	0 / 0	100%	16.22	29 / 29
spleen	100%	1998.56	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	12.33	45 / 45
ureter	0%	0	0 / 0	100%	14.44	1 / 1
muscle	100%	4033.82	801 / 803	0%	0	0 / 0
blood vessel	99%	1664.50	1326 / 1335	0%	0	0 / 0
heart	98%	5702.07	846 / 861	0%	0	0 / 0
peripheral blood	94%	1498.94	872 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0022904	Biological process	respiratory electron transport chain
GO_0033539	Biological process	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GO_0009063	Biological process	amino acid catabolic process
GO_0045251	Cellular component	electron transfer flavoprotein complex
GO_0005759	Cellular component	mitochondrial matrix
GO_0005739	Cellular component	mitochondrion
GO_0005515	Molecular function	protein binding
GO_0009055	Molecular function	electron transfer activity

IV. Literature review

[source]

Gene name	ETFB
Protein name	Electron transfer flavoprotein subunit beta (Beta-ETF) Electron transfer flavoprotein subunit beta
Synonyms	FP585
Description	FUNCTION: Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase . It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (Probable). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism . ETFB binds an AMP molecule that probably has a purely structural role . .
Accessions	ENST00000596253.1 M0QY67 P38117 ENST00000354232.8 [P38117-2] ENST00000309244.9 [P38117-1]

ETFB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review