ECH1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
fibroblast	29 studies	27% ± 13%	Explore
natural killer cell	25 studies	33% ± 10%	Explore
B cell	23 studies	26% ± 9%	Explore
endothelial cell	23 studies	29% ± 13%	Explore
smooth muscle cell	21 studies	29% ± 11%	Explore
CD8-positive, alpha-beta T cell	21 studies	29% ± 11%	Explore
T cell	19 studies	25% ± 7%	Explore
CD4-positive, alpha-beta T cell	19 studies	29% ± 12%	Explore
pericyte	19 studies	29% ± 8%	Explore
macrophage	18 studies	30% ± 13%	Explore
regulatory T cell	18 studies	28% ± 11%	Explore
epithelial cell	17 studies	42% ± 19%	Explore
conventional dendritic cell	16 studies	29% ± 15%	Explore
basal cell	16 studies	35% ± 18%	Explore
classical monocyte	16 studies	26% ± 12%	Explore
non-classical monocyte	13 studies	27% ± 12%	Explore
memory B cell	13 studies	23% ± 5%	Explore
gamma-delta T cell	12 studies	29% ± 14%	Explore
ciliated cell	12 studies	42% ± 16%	Explore
mast cell	11 studies	29% ± 3%	Explore
endothelial cell of lymphatic vessel	11 studies	27% ± 9%	Explore
mature NK T cell	11 studies	30% ± 6%	Explore
myofibroblast cell	11 studies	28% ± 10%	Explore
connective tissue cell	11 studies	26% ± 8%	Explore
monocyte	11 studies	23% ± 7%	Explore
plasma cell	10 studies	37% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	28% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	29% ± 9%	Explore
goblet cell	10 studies	38% ± 15%	Explore
naive B cell	10 studies	21% ± 5%	Explore
secretory cell	9 studies	30% ± 18%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	29% ± 11%	Explore
capillary endothelial cell	9 studies	22% ± 4%	Explore
type I pneumocyte	8 studies	28% ± 11%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	22% ± 6%	Explore
progenitor cell	8 studies	42% ± 14%	Explore
endothelial cell of artery	8 studies	24% ± 9%	Explore
abnormal cell	8 studies	31% ± 14%	Explore
plasmacytoid dendritic cell	8 studies	29% ± 8%	Explore
type II pneumocyte	7 studies	40% ± 16%	Explore
plasmablast	7 studies	46% ± 23%	Explore
epithelial cell of proximal tubule	7 studies	51% ± 15%	Explore
enterocyte	7 studies	34% ± 13%	Explore
vein endothelial cell	7 studies	23% ± 6%	Explore
endothelial cell of vascular tree	7 studies	26% ± 5%	Explore
myeloid cell	7 studies	24% ± 9%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	29% ± 14%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	30% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	27% ± 8%	Explore
kidney loop of Henle epithelial cell	6 studies	35% ± 10%	Explore
intestinal crypt stem cell	6 studies	44% ± 15%	Explore
transit amplifying cell	6 studies	38% ± 17%	Explore
dendritic cell	6 studies	39% ± 18%	Explore
innate lymphoid cell	6 studies	26% ± 6%	Explore
alveolar macrophage	5 studies	33% ± 6%	Explore
hematopoietic precursor cell	5 studies	41% ± 21%	Explore
leukocyte	5 studies	25% ± 9%	Explore
renal alpha-intercalated cell	5 studies	40% ± 7%	Explore
enteroendocrine cell	5 studies	41% ± 15%	Explore
erythroblast	5 studies	35% ± 11%	Explore
mucosal invariant T cell	5 studies	27% ± 4%	Explore
club cell	5 studies	30% ± 13%	Explore
T follicular helper cell	5 studies	25% ± 4%	Explore
pancreatic A cell	4 studies	46% ± 18%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	44% ± 11%	Explore
mesothelial cell	4 studies	30% ± 18%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	35% ± 16%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	30% ± 10%	Explore
neuron	4 studies	35% ± 17%	Explore
hepatocyte	4 studies	46% ± 33%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	37% ± 12%	Explore
brush cell	4 studies	25% ± 9%	Explore
T-helper 17 cell	4 studies	32% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	19% ± 2%	Explore
type B pancreatic cell	3 studies	46% ± 7%	Explore
mononuclear phagocyte	3 studies	35% ± 14%	Explore
exhausted T cell	3 studies	43% ± 7%	Explore
retinal ganglion cell	3 studies	53% ± 26%	Explore
extravillous trophoblast	3 studies	51% ± 15%	Explore
placental villous trophoblast	3 studies	65% ± 28%	Explore
common myeloid progenitor	3 studies	35% ± 17%	Explore
hematopoietic stem cell	3 studies	29% ± 12%	Explore
lymphocyte	3 studies	33% ± 13%	Explore
pro-B cell	3 studies	21% ± 1%	Explore
precursor B cell	3 studies	19% ± 1%	Explore
mucus secreting cell	3 studies	31% ± 9%	Explore
serous secreting cell	3 studies	26% ± 1%	Explore
intraepithelial lymphocyte	3 studies	39% ± 5%	Explore
germinal center B cell	3 studies	23% ± 2%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	48% ± 25%	Explore
pancreatic ductal cell	3 studies	55% ± 21%	Explore
oligodendrocyte precursor cell	3 studies	27% ± 12%	Explore
group 3 innate lymphoid cell	3 studies	39% ± 12%	Explore
oligodendrocyte	3 studies	18% ± 2%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	14 studies	34% ± 14%	Explore
intestine	11 studies	30% ± 13%	Explore
peripheral blood	9 studies	32% ± 9%	Explore
kidney	7 studies	34% ± 10%	Explore
liver	7 studies	27% ± 13%	Explore
lymph node	5 studies	22% ± 4%	Explore
uterus	4 studies	33% ± 9%	Explore
brain	4 studies	20% ± 5%	Explore
pancreas	3 studies	49% ± 8%	Explore
bone marrow	3 studies	21% ± 4%	Explore
adrenal gland	3 studies	21% ± 3%	Explore
prostate	3 studies	20% ± 6%	Explore
skin	3 studies	16% ± 1%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	16809.89	258 / 258	100%	129.48	230 / 230
ovary	100%	5360.11	180 / 180	100%	132.71	430 / 430
uterus	100%	5862.90	170 / 170	100%	152.59	459 / 459
kidney	100%	12277.25	89 / 89	100%	195.29	897 / 901
thymus	100%	6925.28	650 / 653	100%	139.23	605 / 605
esophagus	100%	8236.83	1444 / 1445	99%	97.90	182 / 183
skin	100%	5924.73	1803 / 1809	99%	102.99	468 / 472
prostate	100%	5963.92	244 / 245	99%	169.02	498 / 502
brain	99%	4376.73	2607 / 2642	100%	93.71	705 / 705
liver	100%	16439.89	225 / 226	99%	239.62	402 / 406
breast	100%	9963.57	459 / 459	99%	108.78	1102 / 1118
bladder	100%	7314.24	21 / 21	98%	142.39	496 / 504
intestine	100%	10389.87	966 / 966	98%	134.06	518 / 527
pancreas	98%	4099.95	321 / 328	100%	129.23	178 / 178
lung	99%	6567.84	575 / 578	98%	111.01	1131 / 1155
stomach	100%	7417.77	359 / 359	97%	120.98	276 / 286
adipose	100%	9768.27	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	135.49	80 / 80
lymph node	0%	0	0 / 0	100%	175.11	29 / 29
muscle	100%	22187.83	803 / 803	0%	0	0 / 0
spleen	100%	10300.77	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	106.71	45 / 45
ureter	0%	0	0 / 0	100%	149.67	1 / 1
heart	99%	19371.73	852 / 861	0%	0	0 / 0
blood vessel	99%	5179.76	1320 / 1335	0%	0	0 / 0
peripheral blood	94%	5188.88	872 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0