EAPP | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	25 studies	25% ± 7%	Explore
B cell	19 studies	26% ± 9%	Explore
regulatory T cell	18 studies	26% ± 6%	Explore
CD8-positive, alpha-beta T cell	17 studies	24% ± 7%	Explore
CD4-positive, alpha-beta T cell	17 studies	24% ± 9%	Explore
fibroblast	17 studies	25% ± 10%	Explore
T cell	15 studies	20% ± 5%	Explore
ciliated cell	14 studies	30% ± 14%	Explore
naive B cell	14 studies	26% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	27% ± 7%	Explore
endothelial cell	12 studies	27% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	29% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	11 studies	26% ± 7%	Explore
mature NK T cell	11 studies	23% ± 4%	Explore
memory B cell	11 studies	25% ± 6%	Explore
pericyte	11 studies	22% ± 5%	Explore
gamma-delta T cell	11 studies	28% ± 11%	Explore
non-classical monocyte	10 studies	26% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	29% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	26% ± 9%	Explore
mucosal invariant T cell	9 studies	22% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	22% ± 5%	Explore
basal cell	8 studies	29% ± 13%	Explore
smooth muscle cell	8 studies	22% ± 7%	Explore
plasmacytoid dendritic cell	8 studies	25% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	28% ± 10%	Explore
connective tissue cell	7 studies	23% ± 5%	Explore
epithelial cell	7 studies	38% ± 19%	Explore
classical monocyte	6 studies	27% ± 8%	Explore
capillary endothelial cell	6 studies	18% ± 1%	Explore
endothelial cell of vascular tree	6 studies	19% ± 2%	Explore
endothelial cell of lymphatic vessel	6 studies	21% ± 6%	Explore
T follicular helper cell	6 studies	22% ± 4%	Explore
precursor B cell	5 studies	27% ± 10%	Explore
myofibroblast cell	5 studies	21% ± 3%	Explore
astrocyte	5 studies	26% ± 10%	Explore
neuron	5 studies	28% ± 13%	Explore
glutamatergic neuron	5 studies	33% ± 16%	Explore
abnormal cell	5 studies	21% ± 4%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	24% ± 6%	Explore
exhausted T cell	4 studies	26% ± 10%	Explore
plasma cell	4 studies	26% ± 10%	Explore
pro-B cell	4 studies	28% ± 6%	Explore
type I pneumocyte	4 studies	22% ± 5%	Explore
innate lymphoid cell	4 studies	23% ± 4%	Explore
macrophage	4 studies	21% ± 5%	Explore
GABAergic neuron	4 studies	31% ± 10%	Explore
goblet cell	4 studies	31% ± 8%	Explore
intestinal crypt stem cell	4 studies	23% ± 5%	Explore
mast cell	4 studies	21% ± 2%	Explore
oligodendrocyte	4 studies	20% ± 3%	Explore
hematopoietic stem cell	4 studies	22% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	22% ± 7%	Explore
secretory cell	3 studies	28% ± 13%	Explore
leukocyte	3 studies	25% ± 7%	Explore
conventional dendritic cell	3 studies	36% ± 14%	Explore
hematopoietic precursor cell	3 studies	32% ± 17%	Explore
plasmablast	3 studies	38% ± 13%	Explore
kidney loop of Henle epithelial cell	3 studies	23% ± 2%	Explore
mesothelial cell	3 studies	34% ± 19%	Explore
neural crest cell	3 studies	19% ± 2%	Explore
retinal bipolar neuron	3 studies	33% ± 14%	Explore
club cell	3 studies	22% ± 7%	Explore
immature B cell	3 studies	27% ± 4%	Explore
amacrine cell	3 studies	39% ± 6%	Explore
retina horizontal cell	3 studies	27% ± 10%	Explore
retinal rod cell	3 studies	31% ± 9%	Explore
Mueller cell	3 studies	30% ± 1%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	34% ± 16%	Explore
granulocyte	3 studies	21% ± 3%	Explore
enteroendocrine cell	3 studies	31% ± 12%	Explore
glial cell	3 studies	25% ± 13%	Explore
vein endothelial cell	3 studies	19% ± 5%	Explore
group 3 innate lymphoid cell	3 studies	26% ± 12%	Explore
interneuron	3 studies	31% ± 14%	Explore
double negative thymocyte	3 studies	39% ± 8%	Explore
oligodendrocyte precursor cell	3 studies	23% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	27% ± 7%	Explore
lung	8 studies	24% ± 10%	Explore
brain	6 studies	27% ± 10%	Explore
intestine	6 studies	21% ± 8%	Explore
eye	5 studies	29% ± 9%	Explore
pancreas	3 studies	21% ± 8%	Explore
kidney	3 studies	17% ± 1%	Explore
bone marrow	3 studies	19% ± 2%	Explore
liver	3 studies	26% ± 11%	Explore
lymph node	3 studies	20% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1558.15	1445 / 1445	100%	45.55	183 / 183
ovary	100%	2442.17	180 / 180	100%	60.99	430 / 430
prostate	100%	1615.54	245 / 245	100%	72.58	502 / 502
stomach	100%	1329.91	359 / 359	100%	49.23	286 / 286
uterus	100%	1998.92	170 / 170	100%	60.67	459 / 459
breast	100%	2383.86	459 / 459	100%	82.43	1117 / 1118
kidney	100%	1434.79	89 / 89	100%	53.12	898 / 901
intestine	100%	2195.63	966 / 966	100%	56.18	525 / 527
bladder	100%	1751.95	21 / 21	100%	52.86	502 / 504
liver	100%	963.49	226 / 226	100%	40.67	404 / 406
thymus	100%	1815.32	653 / 653	100%	85.15	602 / 605
lung	99%	1418.28	575 / 578	100%	61.21	1155 / 1155
brain	99%	1378.74	2626 / 2642	100%	66.44	705 / 705
adrenal gland	100%	2097.88	258 / 258	99%	55.33	228 / 230
skin	100%	2413.34	1809 / 1809	99%	49.26	465 / 472
pancreas	98%	858.07	321 / 328	100%	51.18	178 / 178
adipose	100%	2033.72	1204 / 1204	0%	0	0 / 0
blood vessel	100%	1986.25	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	58.87	29 / 29
spleen	100%	1778.06	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	57.37	45 / 45
ureter	0%	0	0 / 0	100%	23.45	1 / 1
muscle	100%	1300.49	799 / 803	0%	0	0 / 0
heart	97%	824.54	833 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	96%	45.59	77 / 80
peripheral blood	96%	1353.19	892 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0034244	Biological process	negative regulation of transcription elongation by RNA polymerase II
GO_0032968	Biological process	positive regulation of transcription elongation by RNA polymerase II
GO_0016607	Cellular component	nuclear speck
GO_0005654	Cellular component	nucleoplasm
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	EAPP
Protein name	E2F associated phosphoprotein E2F-associated phosphoprotein (EAPP) Alternative protein EAPP
Synonyms	C14orf11 BM-036
Description	FUNCTION: May play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression. .
Accessions	ENST00000555705.1 G3V5N6 L8EAZ8 G3V2W9 ENST00000554792.1 Q56P03 ENST00000250454.8

EAPP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review