DNAJC19 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	18 studies	19% ± 5%	Explore
CD8-positive, alpha-beta T cell	17 studies	20% ± 5%	Explore
natural killer cell	15 studies	20% ± 5%	Explore
CD4-positive, alpha-beta T cell	15 studies	20% ± 4%	Explore
pericyte	14 studies	20% ± 4%	Explore
mast cell	13 studies	24% ± 5%	Explore
fibroblast	13 studies	24% ± 9%	Explore
regulatory T cell	13 studies	18% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	11 studies	22% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	23% ± 4%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	19% ± 4%	Explore
T cell	10 studies	19% ± 4%	Explore
naive B cell	10 studies	18% ± 3%	Explore
gamma-delta T cell	10 studies	23% ± 13%	Explore
memory B cell	10 studies	20% ± 3%	Explore
epithelial cell	9 studies	38% ± 20%	Explore
smooth muscle cell	9 studies	22% ± 5%	Explore
connective tissue cell	8 studies	21% ± 5%	Explore
endothelial cell	8 studies	28% ± 11%	Explore
mucosal invariant T cell	8 studies	19% ± 3%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	20% ± 4%	Explore
basal cell	7 studies	29% ± 17%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	20% ± 2%	Explore
epithelial cell of proximal tubule	7 studies	23% ± 4%	Explore
mature NK T cell	7 studies	17% ± 2%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	18% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	6 studies	17% ± 2%	Explore
kidney loop of Henle epithelial cell	6 studies	41% ± 11%	Explore
abnormal cell	6 studies	28% ± 4%	Explore
ciliated cell	6 studies	34% ± 12%	Explore
endothelial cell of lymphatic vessel	6 studies	20% ± 7%	Explore
plasmacytoid dendritic cell	6 studies	25% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	23% ± 3%	Explore
erythroblast	5 studies	32% ± 11%	Explore
myofibroblast cell	5 studies	18% ± 2%	Explore
T follicular helper cell	5 studies	21% ± 2%	Explore
endothelial cell of vascular tree	5 studies	20% ± 3%	Explore
conventional dendritic cell	4 studies	28% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	30% ± 7%	Explore
progenitor cell	4 studies	19% ± 5%	Explore
plasma cell	4 studies	28% ± 11%	Explore
innate lymphoid cell	4 studies	18% ± 1%	Explore
hematopoietic stem cell	4 studies	17% ± 2%	Explore
hematopoietic precursor cell	3 studies	34% ± 9%	Explore
pancreatic A cell	3 studies	27% ± 3%	Explore
type B pancreatic cell	3 studies	39% ± 8%	Explore
non-classical monocyte	3 studies	24% ± 5%	Explore
type I pneumocyte	3 studies	31% ± 6%	Explore
type II pneumocyte	3 studies	34% ± 16%	Explore
exhausted T cell	3 studies	18% ± 1%	Explore
macrophage	3 studies	25% ± 5%	Explore
GABAergic neuron	3 studies	27% ± 8%	Explore
glutamatergic neuron	3 studies	34% ± 12%	Explore
dendritic cell	3 studies	34% ± 11%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	38% ± 20%	Explore
goblet cell	3 studies	28% ± 11%	Explore
intestinal crypt stem cell	3 studies	24% ± 4%	Explore
group 3 innate lymphoid cell	3 studies	24% ± 11%	Explore
T-helper 17 cell	3 studies	18% ± 2%	Explore
double negative thymocyte	3 studies	31% ± 18%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	29% ± 6%	Explore
neuron	3 studies	32% ± 16%	Explore
oligodendrocyte precursor cell	3 studies	18% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	11 studies	20% ± 4%	Explore
kidney	7 studies	20% ± 4%	Explore
lung	7 studies	26% ± 12%	Explore
brain	5 studies	24% ± 9%	Explore
lymph node	4 studies	22% ± 4%	Explore
pancreas	3 studies	32% ± 6%	Explore
liver	3 studies	31% ± 17%	Explore
intestine	3 studies	25% ± 12%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	1308.81	21 / 21	100%	24.95	504 / 504
esophagus	100%	1281.48	1445 / 1445	100%	24.27	183 / 183
intestine	100%	1331.55	966 / 966	100%	22.09	527 / 527
liver	100%	1328.27	226 / 226	100%	24.64	406 / 406
ovary	100%	1359.47	180 / 180	100%	44.06	430 / 430
pancreas	100%	891.15	328 / 328	100%	18.27	178 / 178
prostate	100%	1398.51	245 / 245	100%	35.75	502 / 502
uterus	100%	1245.38	170 / 170	100%	30.29	459 / 459
kidney	100%	1881.58	89 / 89	100%	24.10	900 / 901
brain	100%	1368.16	2638 / 2642	100%	25.68	705 / 705
breast	100%	1393.79	459 / 459	100%	36.49	1116 / 1118
thymus	100%	1270.53	653 / 653	100%	25.64	603 / 605
stomach	100%	1224.18	359 / 359	100%	22.28	285 / 286
adrenal gland	100%	2239.57	258 / 258	100%	24.99	229 / 230
lung	99%	919.65	574 / 578	100%	30.22	1155 / 1155
skin	100%	937.56	1804 / 1809	97%	17.47	457 / 472
adipose	100%	1244.93	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	22.19	29 / 29
muscle	100%	2263.65	803 / 803	0%	0	0 / 0
spleen	100%	978.42	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	27.63	45 / 45
ureter	0%	0	0 / 0	100%	13.35	1 / 1
blood vessel	100%	1542.01	1334 / 1335	0%	0	0 / 0
heart	99%	1806.54	852 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	86%	10.89	69 / 80
peripheral blood	34%	342.16	320 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006457	Biological process	protein folding
GO_0007601	Biological process	visual perception
GO_0030150	Biological process	protein import into mitochondrial matrix
GO_1900208	Biological process	regulation of cardiolipin metabolic process
GO_0006886	Biological process	intracellular protein transport
GO_0006626	Biological process	protein targeting to mitochondrion
GO_0048806	Biological process	genitalia development
GO_0001405	Cellular component	PAM complex, Tim23 associated import motor
GO_0005744	Cellular component	TIM23 mitochondrial import inner membrane translocase complex
GO_0032991	Cellular component	protein-containing complex
GO_0098800	Cellular component	inner mitochondrial membrane protein complex
GO_0099617	Cellular component	matrix side of mitochondrial inner membrane
GO_0016020	Cellular component	membrane
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0005739	Cellular component	mitochondrion
GO_0005515	Molecular function	protein binding
GO_0001671	Molecular function	ATPase activator activity

IV. Literature review

[source]

Gene name	DNAJC19
Protein name	DnaJ heat shock protein family (Hsp40) member C19 DnaJ (Hsp40) homolog, subfamily C, member 19, isoform CRA_b (DnaJ heat shock protein family (Hsp40) member C19) (DnaJ-like protein subfamily C member 19 isoform 2) Mitochondrial import inner membrane translocase subunit TIM14 (DnaJ homolog subfamily C member 19) Mitochondrial import inner membrane translocase subunit TIM14
Synonyms	TIMM14 TIM14 hCG_17532
Description	FUNCTION: Mitochondrial co-chaperone which forms a complex with prohibitins to regulate cardiolipin remodeling (By similarity). May be a component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity). .
Accessions	A0A0S2Z5X1 ENST00000469657.5 ENST00000643241.1 A0A2R8Y839 ENST00000688055.1 F2Z3A7 ENST00000491873.5 [Q96DA6-2] ENST00000646965.1 ENST00000486355.1 ENST00000382564.8 [Q96DA6-1] A0A2R8Y817 Q96DA6 A0A8I5KQT8 G5E9V2 ENST00000479269.5 [Q96DA6-2]

DNAJC19 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review