CHURC1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	27 studies	26% ± 9%	Explore
endothelial cell	27 studies	30% ± 12%	Explore
CD4-positive, alpha-beta T cell	27 studies	32% ± 10%	Explore
natural killer cell	26 studies	26% ± 6%	Explore
CD8-positive, alpha-beta T cell	26 studies	31% ± 8%	Explore
pericyte	24 studies	32% ± 12%	Explore
smooth muscle cell	24 studies	31% ± 12%	Explore
fibroblast	23 studies	27% ± 12%	Explore
regulatory T cell	22 studies	36% ± 11%	Explore
macrophage	20 studies	25% ± 7%	Explore
non-classical monocyte	20 studies	31% ± 13%	Explore
classical monocyte	20 studies	27% ± 9%	Explore
T cell	18 studies	28% ± 9%	Explore
conventional dendritic cell	17 studies	26% ± 13%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	15 studies	31% ± 9%	Explore
ciliated cell	15 studies	36% ± 18%	Explore
naive B cell	15 studies	23% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	33% ± 11%	Explore
gamma-delta T cell	13 studies	29% ± 12%	Explore
mature NK T cell	12 studies	27% ± 6%	Explore
memory B cell	12 studies	24% ± 4%	Explore
plasmacytoid dendritic cell	12 studies	30% ± 8%	Explore
mast cell	11 studies	26% ± 6%	Explore
monocyte	11 studies	25% ± 8%	Explore
endothelial cell of lymphatic vessel	11 studies	29% ± 9%	Explore
capillary endothelial cell	11 studies	22% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	23% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	25% ± 7%	Explore
endothelial cell of artery	10 studies	26% ± 7%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	33% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	30% ± 15%	Explore
vein endothelial cell	9 studies	24% ± 6%	Explore
mucosal invariant T cell	9 studies	28% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	28% ± 9%	Explore
myofibroblast cell	8 studies	24% ± 5%	Explore
connective tissue cell	8 studies	25% ± 6%	Explore
endothelial cell of vascular tree	8 studies	29% ± 9%	Explore
secretory cell	7 studies	26% ± 12%	Explore
epithelial cell	7 studies	40% ± 22%	Explore
T follicular helper cell	7 studies	34% ± 9%	Explore
basal cell	6 studies	40% ± 14%	Explore
leukocyte	6 studies	28% ± 6%	Explore
precursor B cell	6 studies	29% ± 9%	Explore
innate lymphoid cell	6 studies	23% ± 5%	Explore
astrocyte	6 studies	30% ± 11%	Explore
plasma cell	5 studies	25% ± 10%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	31% ± 11%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	34% ± 8%	Explore
dendritic cell	5 studies	35% ± 18%	Explore
myeloid cell	5 studies	31% ± 14%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	40% ± 10%	Explore
oligodendrocyte	5 studies	22% ± 7%	Explore
type I pneumocyte	4 studies	24% ± 8%	Explore
CD4-positive helper T cell	4 studies	25% ± 9%	Explore
hematopoietic precursor cell	4 studies	33% ± 14%	Explore
plasmablast	4 studies	49% ± 19%	Explore
pancreatic A cell	4 studies	35% ± 11%	Explore
mononuclear phagocyte	4 studies	33% ± 11%	Explore
exhausted T cell	4 studies	36% ± 12%	Explore
kidney loop of Henle epithelial cell	4 studies	22% ± 2%	Explore
progenitor cell	4 studies	18% ± 4%	Explore
epithelial cell of proximal tubule	4 studies	21% ± 3%	Explore
retinal ganglion cell	4 studies	60% ± 24%	Explore
lymphocyte	4 studies	30% ± 8%	Explore
pro-B cell	4 studies	28% ± 5%	Explore
immature B cell	4 studies	23% ± 2%	Explore
retinal rod cell	4 studies	26% ± 8%	Explore
alveolar macrophage	4 studies	29% ± 2%	Explore
neuron	4 studies	30% ± 11%	Explore
abnormal cell	4 studies	24% ± 6%	Explore
goblet cell	4 studies	23% ± 9%	Explore
T-helper 17 cell	4 studies	32% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	23% ± 4%	Explore
oligodendrocyte precursor cell	4 studies	24% ± 6%	Explore
type B pancreatic cell	3 studies	49% ± 5%	Explore
glomerular endothelial cell	3 studies	35% ± 3%	Explore
retinal bipolar neuron	3 studies	26% ± 7%	Explore
megakaryocyte	3 studies	19% ± 3%	Explore
club cell	3 studies	25% ± 8%	Explore
retina horizontal cell	3 studies	24% ± 7%	Explore
retinal cone cell	3 studies	37% ± 10%	Explore
Mueller cell	3 studies	34% ± 6%	Explore
germinal center B cell	3 studies	31% ± 3%	Explore
intermediate monocyte	3 studies	33% ± 17%	Explore
mesothelial cell	3 studies	33% ± 17%	Explore
pancreatic ductal cell	3 studies	37% ± 9%	Explore
enteroendocrine cell	3 studies	27% ± 13%	Explore
intestinal crypt stem cell	3 studies	20% ± 4%	Explore
group 3 innate lymphoid cell	3 studies	30% ± 12%	Explore
neutrophil	3 studies	19% ± 1%	Explore
T-helper 1 cell	3 studies	34% ± 2%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	30% ± 6%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	24% ± 2%	Explore
double negative thymocyte	3 studies	36% ± 15%	Explore
microglial cell	3 studies	20% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	31% ± 10%	Explore
lung	10 studies	33% ± 11%	Explore
intestine	10 studies	20% ± 9%	Explore
eye	7 studies	25% ± 9%	Explore
kidney	6 studies	22% ± 6%	Explore
brain	5 studies	27% ± 6%	Explore
liver	5 studies	27% ± 15%	Explore
pancreas	4 studies	36% ± 13%	Explore
uterus	4 studies	34% ± 13%	Explore
lymph node	3 studies	31% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	2929.83	577 / 578	100%	22.33	1153 / 1155
esophagus	100%	3693.73	1445 / 1445	99%	21.80	182 / 183
brain	99%	3025.79	2627 / 2642	100%	42.41	705 / 705
prostate	100%	2935.28	244 / 245	100%	25.07	501 / 502
breast	100%	3776.77	459 / 459	99%	33.24	1111 / 1118
thymus	100%	2715.15	653 / 653	99%	28.86	601 / 605
uterus	100%	3670.91	170 / 170	98%	19.18	450 / 459
ovary	100%	3319.62	180 / 180	98%	15.96	420 / 430
stomach	100%	2638.86	359 / 359	98%	19.92	279 / 286
intestine	100%	3997.23	966 / 966	98%	19.91	514 / 527
bladder	100%	3999.67	21 / 21	96%	17.69	485 / 504
kidney	100%	2718.89	89 / 89	96%	23.91	865 / 901
adrenal gland	100%	3980.83	258 / 258	95%	26.23	218 / 230
skin	100%	3200.02	1808 / 1809	93%	24.09	441 / 472
pancreas	94%	1403.27	308 / 328	98%	22.55	175 / 178
liver	100%	1467.92	225 / 226	88%	12.66	358 / 406
adipose	100%	4047.01	1204 / 1204	0%	0	0 / 0
blood vessel	100%	6611.90	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	19.05	29 / 29
muscle	100%	4766.79	803 / 803	0%	0	0 / 0
spleen	100%	3140.48	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	20.32	45 / 45
ureter	0%	0	0 / 0	100%	6.89	1 / 1
heart	97%	3113.89	833 / 861	0%	0	0 / 0
peripheral blood	82%	2291.74	762 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	78%	15.62	62 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	CHURC1
Protein name	Protein Churchill
Synonyms	C14orf52 CHCH My015
Description	FUNCTION: Transcriptional activator that mediates FGF signaling during neural development (By similarity). Plays a role in the regulation of cell movement (By similarity). .; FUNCTION: [Isoform 4]: Does not bind DNA by itself. .
Accessions	ENST00000552002.7 [Q8WUH1-4] B7Z3N2 Q8WUH1 ENST00000551093.6 ENST00000547625.1 H0YHB4 ENST00000607599.6 [Q8WUH1-2] ENST00000551947.6 ENST00000548752.7 [Q8WUH1-3] ENST00000549115.7 [Q8WUH1-4] H0YID9

GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0008543	Biological process	fibroblast growth factor receptor signaling pathway
GO_0008270	Molecular function	zinc ion binding
GO_0005515	Molecular function	protein binding

CHURC1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review