ATP1B3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	44 studies	37% ± 13%	Explore
macrophage	40 studies	42% ± 17%	Explore
pericyte	34 studies	37% ± 17%	Explore
fibroblast	32 studies	31% ± 17%	Explore
natural killer cell	31 studies	26% ± 10%	Explore
smooth muscle cell	28 studies	33% ± 16%	Explore
conventional dendritic cell	26 studies	37% ± 17%	Explore
non-classical monocyte	23 studies	48% ± 18%	Explore
classical monocyte	23 studies	37% ± 19%	Explore
CD8-positive, alpha-beta T cell	23 studies	26% ± 10%	Explore
monocyte	22 studies	41% ± 17%	Explore
basal cell	21 studies	48% ± 17%	Explore
mast cell	20 studies	33% ± 13%	Explore
endothelial cell of lymphatic vessel	20 studies	37% ± 13%	Explore
dendritic cell	17 studies	45% ± 19%	Explore
T cell	16 studies	30% ± 12%	Explore
epithelial cell	16 studies	37% ± 19%	Explore
B cell	15 studies	29% ± 15%	Explore
CD4-positive, alpha-beta T cell	15 studies	24% ± 6%	Explore
regulatory T cell	14 studies	24% ± 13%	Explore
myeloid cell	14 studies	42% ± 17%	Explore
capillary endothelial cell	13 studies	30% ± 11%	Explore
connective tissue cell	13 studies	32% ± 16%	Explore
endothelial cell of artery	12 studies	35% ± 15%	Explore
vein endothelial cell	12 studies	37% ± 15%	Explore
microglial cell	12 studies	28% ± 14%	Explore
endothelial cell of vascular tree	12 studies	44% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	22% ± 5%	Explore
mature NK T cell	11 studies	26% ± 9%	Explore
glutamatergic neuron	11 studies	40% ± 26%	Explore
plasmacytoid dendritic cell	11 studies	31% ± 11%	Explore
astrocyte	11 studies	30% ± 10%	Explore
type I pneumocyte	10 studies	29% ± 11%	Explore
gamma-delta T cell	10 studies	31% ± 21%	Explore
oligodendrocyte precursor cell	10 studies	27% ± 10%	Explore
leukocyte	9 studies	38% ± 15%	Explore
myofibroblast cell	9 studies	25% ± 10%	Explore
progenitor cell	9 studies	27% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	28% ± 18%	Explore
alveolar macrophage	8 studies	50% ± 11%	Explore
secretory cell	8 studies	34% ± 14%	Explore
mononuclear phagocyte	7 studies	49% ± 18%	Explore
neuron	7 studies	34% ± 13%	Explore
enterocyte	7 studies	44% ± 8%	Explore
GABAergic neuron	7 studies	44% ± 23%	Explore
oligodendrocyte	7 studies	23% ± 8%	Explore
plasmablast	6 studies	49% ± 19%	Explore
respiratory goblet cell	6 studies	24% ± 8%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	32% ± 14%	Explore
interneuron	6 studies	40% ± 21%	Explore
retinal ganglion cell	6 studies	42% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	20% ± 6%	Explore
hematopoietic precursor cell	5 studies	35% ± 13%	Explore
plasma cell	5 studies	30% ± 15%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	21% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	33% ± 22%	Explore
kidney loop of Henle epithelial cell	5 studies	26% ± 6%	Explore
mesothelial cell	5 studies	30% ± 14%	Explore
transit amplifying cell	5 studies	31% ± 28%	Explore
renal principal cell	5 studies	42% ± 5%	Explore
lymphocyte	5 studies	32% ± 14%	Explore
precursor B cell	5 studies	28% ± 15%	Explore
pro-B cell	5 studies	44% ± 8%	Explore
club cell	5 studies	34% ± 7%	Explore
abnormal cell	5 studies	22% ± 5%	Explore
memory B cell	5 studies	27% ± 15%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	23% ± 6%	Explore
exhausted T cell	4 studies	24% ± 7%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	29% ± 13%	Explore
granule cell	4 studies	29% ± 8%	Explore
mucosal invariant T cell	4 studies	18% ± 1%	Explore
innate lymphoid cell	4 studies	40% ± 20%	Explore
ciliated cell	4 studies	35% ± 15%	Explore
adipocyte	4 studies	32% ± 5%	Explore
T follicular helper cell	4 studies	23% ± 6%	Explore
type II pneumocyte	4 studies	25% ± 14%	Explore
keratinocyte	4 studies	53% ± 18%	Explore
duct epithelial cell	3 studies	31% ± 2%	Explore
hillock cell	3 studies	55% ± 16%	Explore
squamous epithelial cell	3 studies	34% ± 21%	Explore
pancreatic A cell	3 studies	34% ± 9%	Explore
type B pancreatic cell	3 studies	36% ± 14%	Explore
monocyte-derived dendritic cell	3 studies	58% ± 11%	Explore
naive B cell	3 studies	31% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	31% ± 17%	Explore
glomerular endothelial cell	3 studies	23% ± 7%	Explore
neural crest cell	3 studies	39% ± 15%	Explore
extravillous trophoblast	3 studies	23% ± 6%	Explore
placental villous trophoblast	3 studies	60% ± 11%	Explore
amacrine cell	3 studies	37% ± 4%	Explore
retinal pigment epithelial cell	3 studies	31% ± 13%	Explore
tissue-resident macrophage	3 studies	45% ± 10%	Explore
Mueller cell	3 studies	30% ± 9%	Explore
chondrocyte	3 studies	20% ± 5%	Explore
erythroblast	3 studies	41% ± 28%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	31% ± 20%	Explore
intermediate monocyte	3 studies	65% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	37% ± 15%	Explore
granulocyte	3 studies	47% ± 23%	Explore
muscle cell	3 studies	43% ± 13%	Explore
pancreatic ductal cell	3 studies	40% ± 17%	Explore
neutrophil	3 studies	30% ± 13%	Explore
enteroendocrine cell	3 studies	32% ± 4%	Explore
goblet cell	3 studies	26% ± 3%	Explore
group 3 innate lymphoid cell	3 studies	26% ± 12%	Explore
T-helper 17 cell	3 studies	30% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	17% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	17 studies	34% ± 10%	Explore
brain	14 studies	34% ± 18%	Explore
intestine	12 studies	24% ± 8%	Explore
peripheral blood	9 studies	27% ± 11%	Explore
kidney	6 studies	24% ± 5%	Explore
uterus	5 studies	37% ± 6%	Explore
liver	5 studies	35% ± 21%	Explore
placenta	4 studies	39% ± 16%	Explore
bone marrow	4 studies	23% ± 7%	Explore
eye	4 studies	30% ± 10%	Explore
adipose	4 studies	20% ± 4%	Explore
esophagus	4 studies	29% ± 11%	Explore
breast	4 studies	30% ± 8%	Explore
pancreas	3 studies	35% ± 10%	Explore
heart	3 studies	20% ± 1%	Explore
adrenal gland	3 studies	25% ± 2%	Explore
thymus	3 studies	35% ± 14%	Explore
lymph node	3 studies	27% ± 4%	Explore
prostate	3 studies	52% ± 5%	Explore
skin	3 studies	38% ± 16%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	6838.43	1442 / 1445	100%	382.03	183 / 183
intestine	100%	8010.30	966 / 966	99%	207.63	524 / 527
uterus	99%	5210.74	169 / 170	100%	385.74	459 / 459
bladder	100%	5743.33	21 / 21	99%	216.75	500 / 504
skin	100%	12779.98	1809 / 1809	99%	257.39	467 / 472
lung	100%	11267.46	577 / 578	99%	294.33	1144 / 1155
prostate	100%	6302.91	245 / 245	99%	102.87	496 / 502
breast	100%	5983.89	459 / 459	98%	122.73	1097 / 1118
thymus	99%	5395.79	649 / 653	97%	108.77	588 / 605
brain	96%	4539.81	2547 / 2642	100%	121.70	704 / 705
ovary	94%	10154.38	170 / 180	99%	103.30	424 / 430
kidney	100%	5358.97	89 / 89	93%	84.60	835 / 901
adrenal gland	100%	15286.46	258 / 258	89%	98.58	204 / 230
stomach	79%	3551.31	283 / 359	100%	191.07	286 / 286
pancreas	36%	746.27	117 / 328	97%	141.28	172 / 178
lymph node	0%	0	0 / 0	100%	138.15	29 / 29
spleen	100%	4078.85	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	526.99	45 / 45
ureter	0%	0	0 / 0	100%	83.90	1 / 1
adipose	100%	10244.74	1203 / 1204	0%	0	0 / 0
blood vessel	100%	7912.76	1330 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	93%	76.75	74 / 80
heart	86%	3795.08	737 / 861	0%	0	0 / 0
peripheral blood	79%	3630.56	734 / 929	0%	0	0 / 0
liver	16%	375.07	36 / 226	38%	29.77	154 / 406
muscle	45%	1023.01	362 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0072659	Biological process	protein localization to plasma membrane
GO_0032781	Biological process	positive regulation of ATP-dependent activity
GO_1901018	Biological process	positive regulation of potassium ion transmembrane transporter activity
GO_1903278	Biological process	positive regulation of sodium ion export across plasma membrane
GO_0006883	Biological process	intracellular sodium ion homeostasis
GO_0071805	Biological process	potassium ion transmembrane transport
GO_1990573	Biological process	potassium ion import across plasma membrane
GO_0050821	Biological process	protein stabilization
GO_1903288	Biological process	positive regulation of potassium ion import across plasma membrane
GO_0086009	Biological process	membrane repolarization
GO_0030007	Biological process	intracellular potassium ion homeostasis
GO_0035725	Biological process	sodium ion transmembrane transport
GO_0036376	Biological process	sodium ion export across plasma membrane
GO_0016324	Cellular component	apical plasma membrane
GO_0036126	Cellular component	sperm flagellum
GO_0005890	Cellular component	sodium:potassium-exchanging ATPase complex
GO_0005886	Cellular component	plasma membrane
GO_0070062	Cellular component	extracellular exosome
GO_0042470	Cellular component	melanosome
GO_0016323	Cellular component	basolateral plasma membrane
GO_0030674	Molecular function	protein-macromolecule adaptor activity
GO_0051117	Molecular function	ATPase binding
GO_0005515	Molecular function	protein binding
GO_0001671	Molecular function	ATPase activator activity

IV. Literature review

[source]

Gene name	ATP1B3
Protein name	Sodium/potassium-transporting ATPase subunit beta-3 (Sodium/potassium-dependent ATPase subunit beta-3) (ATPB-3) (CD antigen CD298) ATPase Na+/K+ transporting subunit beta 3 Sodium/potassium-transporting ATPase subunit beta-3 (Sodium/potassium-dependent ATPase subunit beta-3) Sodium/potassium-transporting ATPase subunit beta
Synonyms
Description	FUNCTION: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known. FUNCTION: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known. . FUNCTION: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known. . FUNCTION: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known. . FUNCTION: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known. .
Accessions	F8WBY4 ENST00000475483.5 H7C547 P54709 ENST00000495216.1 ENST00000465172.5 ENST00000286371.8 [P54709-1] C9J6S2 C9JXZ1 ENST00000487199.5 Q58I18 ENST00000466678.5 C9JA36 ENST00000462082.1 H7C4L9

ATP1B3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review