ADRM1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	27 studies	25% ± 9%	Explore
B cell	24 studies	21% ± 6%	Explore
endothelial cell	22 studies	28% ± 11%	Explore
macrophage	21 studies	23% ± 8%	Explore
CD4-positive, alpha-beta T cell	19 studies	27% ± 14%	Explore
regulatory T cell	19 studies	28% ± 10%	Explore
T cell	18 studies	25% ± 8%	Explore
CD8-positive, alpha-beta T cell	18 studies	32% ± 13%	Explore
classical monocyte	17 studies	25% ± 10%	Explore
conventional dendritic cell	16 studies	29% ± 15%	Explore
non-classical monocyte	16 studies	31% ± 14%	Explore
pericyte	16 studies	20% ± 5%	Explore
fibroblast	16 studies	24% ± 10%	Explore
basal cell	14 studies	29% ± 14%	Explore
memory B cell	13 studies	24% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	27% ± 8%	Explore
naive B cell	13 studies	20% ± 5%	Explore
mature NK T cell	13 studies	23% ± 4%	Explore
smooth muscle cell	12 studies	22% ± 7%	Explore
gamma-delta T cell	12 studies	27% ± 11%	Explore
plasma cell	11 studies	37% ± 12%	Explore
ciliated cell	11 studies	31% ± 13%	Explore
capillary endothelial cell	11 studies	25% ± 6%	Explore
plasmacytoid dendritic cell	11 studies	25% ± 9%	Explore
epithelial cell	10 studies	34% ± 17%	Explore
monocyte	10 studies	24% ± 8%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	22% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	26% ± 5%	Explore
endothelial cell of artery	10 studies	25% ± 6%	Explore
vein endothelial cell	10 studies	23% ± 6%	Explore
plasmablast	9 studies	43% ± 22%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	27% ± 9%	Explore
mucosal invariant T cell	9 studies	23% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	18% ± 3%	Explore
connective tissue cell	8 studies	21% ± 5%	Explore
dendritic cell	8 studies	33% ± 20%	Explore
endothelial cell of vascular tree	8 studies	27% ± 7%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	27% ± 8%	Explore
abnormal cell	7 studies	25% ± 7%	Explore
myeloid cell	7 studies	25% ± 9%	Explore
endothelial cell of lymphatic vessel	7 studies	24% ± 8%	Explore
secretory cell	6 studies	31% ± 14%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	37% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	27% ± 4%	Explore
myofibroblast cell	6 studies	21% ± 7%	Explore
innate lymphoid cell	6 studies	23% ± 9%	Explore
mast cell	6 studies	18% ± 4%	Explore
precursor B cell	5 studies	30% ± 8%	Explore
club cell	5 studies	25% ± 8%	Explore
T follicular helper cell	5 studies	21% ± 3%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	30% ± 11%	Explore
hematopoietic precursor cell	4 studies	31% ± 15%	Explore
exhausted T cell	4 studies	35% ± 8%	Explore
immature B cell	4 studies	23% ± 9%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	38% ± 7%	Explore
goblet cell	4 studies	24% ± 6%	Explore
erythrocyte	4 studies	29% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	22% ± 7%	Explore
deuterosomal cell	3 studies	21% ± 7%	Explore
pancreatic A cell	3 studies	33% ± 16%	Explore
leukocyte	3 studies	26% ± 10%	Explore
glomerular endothelial cell	3 studies	21% ± 1%	Explore
retinal ganglion cell	3 studies	57% ± 26%	Explore
placental villous trophoblast	3 studies	38% ± 13%	Explore
lymphocyte	3 studies	30% ± 6%	Explore
pro-B cell	3 studies	21% ± 2%	Explore
alveolar macrophage	3 studies	20% ± 1%	Explore
intraepithelial lymphocyte	3 studies	26% ± 10%	Explore
erythroblast	3 studies	36% ± 23%	Explore
germinal center B cell	3 studies	24% ± 4%	Explore
intermediate monocyte	3 studies	38% ± 17%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	24% ± 3%	Explore
enteroendocrine cell	3 studies	29% ± 12%	Explore
mononuclear phagocyte	3 studies	32% ± 11%	Explore
T-helper 1 cell	3 studies	32% ± 14%	Explore
double negative thymocyte	3 studies	35% ± 9%	Explore
neuron	3 studies	31% ± 16%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	14 studies	26% ± 12%	Explore
peripheral blood	14 studies	26% ± 7%	Explore
lymph node	5 studies	20% ± 4%	Explore
kidney	4 studies	20% ± 4%	Explore
breast	4 studies	20% ± 2%	Explore
pancreas	3 studies	32% ± 15%	Explore
placenta	3 studies	25% ± 12%	Explore
uterus	3 studies	26% ± 12%	Explore
brain	3 studies	21% ± 4%	Explore
intestine	3 studies	25% ± 10%	Explore
liver	3 studies	34% ± 22%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3743.89	1445 / 1445	100%	94.82	183 / 183
liver	100%	2904.36	226 / 226	100%	70.42	406 / 406
ovary	100%	2008.30	180 / 180	100%	94.46	430 / 430
pancreas	100%	2120.02	328 / 328	100%	77.45	178 / 178
uterus	100%	3105.57	170 / 170	100%	107.55	459 / 459
skin	100%	3941.80	1809 / 1809	100%	111.90	471 / 472
thymus	100%	2663.28	652 / 653	100%	63.83	604 / 605
kidney	100%	2725.12	89 / 89	100%	51.22	897 / 901
intestine	100%	3298.94	966 / 966	99%	136.36	524 / 527
brain	99%	2541.60	2624 / 2642	100%	62.22	705 / 705
stomach	100%	2556.89	359 / 359	99%	130.43	284 / 286
prostate	100%	2983.57	245 / 245	99%	67.54	498 / 502
breast	100%	3207.48	459 / 459	99%	71.16	1109 / 1118
adrenal gland	100%	4112.71	258 / 258	99%	60.69	227 / 230
bladder	100%	3371.67	21 / 21	99%	116.30	497 / 504
lung	100%	3340.22	577 / 578	99%	84.88	1140 / 1155
adipose	100%	3483.45	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	102.91	80 / 80
lymph node	0%	0	0 / 0	100%	114.15	29 / 29
muscle	100%	9831.62	803 / 803	0%	0	0 / 0
spleen	100%	3846.72	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	107.64	45 / 45
ureter	0%	0	0 / 0	100%	79.96	1 / 1
blood vessel	100%	3488.41	1334 / 1335	0%	0	0 / 0
heart	99%	2892.74	851 / 861	0%	0	0 / 0
peripheral blood	98%	2737.46	915 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0043248	Biological process	proteasome assembly
GO_0006368	Biological process	transcription elongation by RNA polymerase II
GO_0043161	Biological process	proteasome-mediated ubiquitin-dependent protein catabolic process
GO_0000502	Cellular component	proteasome complex
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005886	Cellular component	plasma membrane
GO_0008541	Cellular component	proteasome regulatory particle, lid subcomplex
GO_0002020	Molecular function	protease binding
GO_0061133	Molecular function	endopeptidase activator activity
GO_0070628	Molecular function	proteasome binding
GO_0005515	Molecular function	protein binding
GO_0140678	Molecular function	molecular function inhibitor activity

IV. Literature review

[source]

Gene name	ADRM1
Protein name	ADRM1 26S proteasome ubiquitin receptor Proteasomal ubiquitin receptor ADRM1 (110 kDa cell membrane glycoprotein) (Gp110) (Adhesion-regulating molecule 1) (ARM-1) (Proteasome regulatory particle non-ATPase 13) (hRpn13) (Rpn13 homolog)
Synonyms	GP110
Description	FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins . This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required . Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair . Within the complex, functions as a proteasomal ubiquitin receptor . Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation . UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex . .
Accessions	ENST00000491935.5 ENST00000620230.4 ENST00000462554.2 A0A087WUX6 ENST00000253003.7 A0A087WX59 Q16186

ADRM1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review