TXNDC17 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	22 studies	30% ± 11%	Explore
endothelial cell	22 studies	28% ± 11%	Explore
classical monocyte	21 studies	31% ± 12%	Explore
epithelial cell	20 studies	45% ± 21%	Explore
non-classical monocyte	19 studies	30% ± 12%	Explore
conventional dendritic cell	18 studies	29% ± 14%	Explore
basal cell	18 studies	44% ± 20%	Explore
monocyte	15 studies	29% ± 9%	Explore
CD8-positive, alpha-beta T cell	15 studies	30% ± 14%	Explore
regulatory T cell	15 studies	28% ± 10%	Explore
pericyte	14 studies	20% ± 5%	Explore
fibroblast	13 studies	23% ± 11%	Explore
natural killer cell	12 studies	23% ± 8%	Explore
plasma cell	11 studies	34% ± 12%	Explore
T cell	11 studies	28% ± 7%	Explore
smooth muscle cell	11 studies	22% ± 4%	Explore
secretory cell	10 studies	34% ± 18%	Explore
progenitor cell	10 studies	38% ± 14%	Explore
myeloid cell	10 studies	32% ± 14%	Explore
plasmablast	9 studies	42% ± 23%	Explore
goblet cell	9 studies	36% ± 14%	Explore
type II pneumocyte	8 studies	42% ± 22%	Explore
ciliated cell	8 studies	42% ± 17%	Explore
capillary endothelial cell	8 studies	22% ± 8%	Explore
enterocyte	8 studies	39% ± 15%	Explore
dendritic cell	8 studies	44% ± 24%	Explore
endothelial cell of lymphatic vessel	8 studies	27% ± 9%	Explore
plasmacytoid dendritic cell	8 studies	24% ± 8%	Explore
type I pneumocyte	7 studies	31% ± 15%	Explore
B cell	7 studies	23% ± 7%	Explore
club cell	7 studies	41% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	19% ± 3%	Explore
CD4-positive, alpha-beta T cell	7 studies	40% ± 17%	Explore
epithelial cell of proximal tubule	7 studies	47% ± 7%	Explore
connective tissue cell	7 studies	24% ± 5%	Explore
abnormal cell	7 studies	39% ± 16%	Explore
endothelial cell of artery	7 studies	21% ± 6%	Explore
gamma-delta T cell	7 studies	25% ± 19%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	26% ± 11%	Explore
ionocyte	6 studies	38% ± 8%	Explore
respiratory goblet cell	6 studies	37% ± 16%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	35% ± 15%	Explore
kidney loop of Henle epithelial cell	6 studies	30% ± 7%	Explore
myofibroblast cell	6 studies	21% ± 3%	Explore
vein endothelial cell	6 studies	24% ± 7%	Explore
transit amplifying cell	6 studies	35% ± 15%	Explore
endothelial cell of vascular tree	6 studies	21% ± 6%	Explore
alveolar macrophage	5 studies	25% ± 6%	Explore
hematopoietic precursor cell	5 studies	30% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	18% ± 2%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	19% ± 3%	Explore
mesothelial cell	5 studies	33% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	29% ± 7%	Explore
pancreatic A cell	4 studies	46% ± 18%	Explore
exhausted T cell	4 studies	32% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	32% ± 3%	Explore
renal alpha-intercalated cell	4 studies	39% ± 8%	Explore
enteroendocrine cell	4 studies	45% ± 6%	Explore
intestinal crypt stem cell	4 studies	34% ± 14%	Explore
erythroblast	4 studies	36% ± 9%	Explore
brush cell	4 studies	33% ± 21%	Explore
precursor B cell	4 studies	26% ± 8%	Explore
neuron	4 studies	28% ± 14%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	28% ± 9%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	32% ± 1%	Explore
neutrophil	4 studies	16% ± 0%	Explore
deuterosomal cell	3 studies	23% ± 9%	Explore
duct epithelial cell	3 studies	30% ± 13%	Explore
leukocyte	3 studies	28% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	21% ± 6%	Explore
mature NK T cell	3 studies	18% ± 1%	Explore
neural crest cell	3 studies	21% ± 1%	Explore
extravillous trophoblast	3 studies	40% ± 11%	Explore
common myeloid progenitor	3 studies	29% ± 9%	Explore
lymphocyte	3 studies	31% ± 11%	Explore
neuroendocrine cell	3 studies	57% ± 15%	Explore
pro-B cell	3 studies	21% ± 3%	Explore
serous secreting cell	3 studies	37% ± 7%	Explore
acinar cell	3 studies	24% ± 8%	Explore
T follicular helper cell	3 studies	21% ± 3%	Explore
germinal center B cell	3 studies	27% ± 5%	Explore
memory B cell	3 studies	23% ± 9%	Explore
intermediate monocyte	3 studies	46% ± 11%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	29% ± 13%	Explore
luminal cell of prostate epithelium	3 studies	24% ± 8%	Explore
pancreatic ductal cell	3 studies	49% ± 7%	Explore
granulocyte monocyte progenitor cell	3 studies	36% ± 19%	Explore
mast cell	3 studies	22% ± 6%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	37% ± 18%	Explore
hepatocyte	3 studies	52% ± 26%	Explore
keratinocyte	3 studies	32% ± 15%	Explore
T-helper 17 cell	3 studies	32% ± 20%	Explore
mononuclear phagocyte	3 studies	32% ± 14%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	32% ± 6%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	33% ± 16%	Explore
peripheral blood	12 studies	24% ± 7%	Explore
intestine	10 studies	28% ± 12%	Explore
kidney	8 studies	28% ± 7%	Explore
liver	5 studies	28% ± 14%	Explore
pancreas	4 studies	41% ± 15%	Explore
bone marrow	4 studies	22% ± 3%	Explore
brain	4 studies	22% ± 5%	Explore
eye	3 studies	21% ± 5%	Explore
uterus	3 studies	31% ± 20%	Explore
adrenal gland	3 studies	23% ± 2%	Explore
esophagus	3 studies	52% ± 23%	Explore
prostate	3 studies	27% ± 6%	Explore
thymus	3 studies	37% ± 12%	Explore
lymph node	3 studies	26% ± 11%	Explore
breast	3 studies	21% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	790.12	328 / 328	100%	33.94	178 / 178
uterus	100%	636.24	170 / 170	100%	65.00	459 / 459
esophagus	100%	2606.13	1443 / 1445	100%	48.29	183 / 183
intestine	100%	1108.64	966 / 966	100%	41.29	526 / 527
stomach	100%	1405.40	358 / 359	100%	37.12	286 / 286
thymus	100%	847.10	652 / 653	100%	29.09	604 / 605
bladder	100%	1316.95	21 / 21	100%	61.01	502 / 504
kidney	100%	1895.89	89 / 89	99%	28.17	896 / 901
prostate	100%	1198.80	245 / 245	99%	45.75	499 / 502
breast	100%	889.73	458 / 459	99%	36.06	1111 / 1118
skin	100%	1291.04	1807 / 1809	99%	31.32	468 / 472
liver	100%	1374.64	226 / 226	99%	34.49	402 / 406
ovary	99%	513.51	178 / 180	100%	27.67	429 / 430
lung	98%	876.07	569 / 578	100%	59.31	1154 / 1155
brain	98%	607.94	2600 / 2642	99%	24.59	701 / 705
adrenal gland	100%	1588.70	258 / 258	94%	21.06	217 / 230
lymph node	0%	0	0 / 0	100%	46.46	29 / 29
spleen	100%	1486.65	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	63.55	45 / 45
ureter	0%	0	0 / 0	100%	46.13	1 / 1
adipose	100%	861.40	1203 / 1204	0%	0	0 / 0
blood vessel	99%	825.00	1326 / 1335	0%	0	0 / 0
heart	96%	713.51	828 / 861	0%	0	0 / 0
muscle	95%	497.75	763 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	95%	17.67	76 / 80
peripheral blood	68%	763.46	628 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	TXNDC17
Protein name	Alternative protein TXNDC17 Thioredoxin domain-containing protein 17 (14 kDa thioredoxin-related protein) (TRP14) (Protein 42-9-9) (Thioredoxin-like protein 5) Thioredoxin domain-containing protein 17
Synonyms	TXNL5
Description	FUNCTION: Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide. .
Accessions	L8E9G3 ENST00000574838.1 I3L3M7 ENST00000250101.10 ENST00000570330.5 I3L2R6 Q9BRA2 I3L0K2 ENST00000574734.5

GO_0098869	Biological process	cellular oxidant detoxification
GO_0033209	Biological process	tumor necrosis factor-mediated signaling pathway
GO_0070062	Cellular component	extracellular exosome
GO_0005829	Cellular component	cytosol
GO_0004601	Molecular function	peroxidase activity
GO_0047134	Molecular function	protein-disulfide reductase (NAD(P)H) activity
GO_0005515	Molecular function	protein binding

TXNDC17 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review