TIMM8B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007605Biological processsensory perception of sound
GO_0006626Biological processprotein targeting to mitochondrion
GO_0045039Biological processprotein insertion into mitochondrial inner membrane
GO_0005615Cellular componentextracellular space
GO_0005758Cellular componentmitochondrial intermembrane space
GO_0042719Cellular componentmitochondrial intermembrane space protein transporter complex
GO_0005743Cellular componentmitochondrial inner membrane
GO_0008270Molecular functionzinc ion binding
GO_0140318Molecular functionprotein transporter activity

IV. Literature review

[source]
Gene nameTIMM8B
Protein nameMitochondrial import inner membrane translocase subunit Tim8 B (DDP-like protein) (Deafness dystonia protein 2)
Translocase of inner mitochondrial membrane 8 homolog B
Mitochondrial import inner membrane translocase subunit
SynonymsTIM8B
DDP2
DDPL
hCG_39462
DescriptionFUNCTION: Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity). .

FUNCTION: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. .

AccessionsE9PIR3
ENST00000509359.6
ENST00000541231.1
ENST00000504148.3
G3XAN8
Q9Y5J9