SPAG7 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	21 studies	20% ± 5%	Explore
ciliated cell	16 studies	35% ± 16%	Explore
fibroblast	14 studies	28% ± 11%	Explore
endothelial cell	12 studies	28% ± 12%	Explore
smooth muscle cell	12 studies	25% ± 6%	Explore
basal cell	11 studies	29% ± 16%	Explore
B cell	11 studies	21% ± 6%	Explore
conventional dendritic cell	11 studies	29% ± 13%	Explore
mast cell	10 studies	22% ± 8%	Explore
classical monocyte	10 studies	24% ± 10%	Explore
CD8-positive, alpha-beta T cell	10 studies	21% ± 4%	Explore
epithelial cell	10 studies	35% ± 19%	Explore
pericyte	10 studies	23% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	20% ± 4%	Explore
T cell	9 studies	19% ± 5%	Explore
non-classical monocyte	8 studies	26% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	23% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	21% ± 3%	Explore
connective tissue cell	8 studies	29% ± 8%	Explore
macrophage	8 studies	25% ± 8%	Explore
endothelial cell of lymphatic vessel	8 studies	24% ± 9%	Explore
plasmacytoid dendritic cell	8 studies	28% ± 9%	Explore
mature NK T cell	7 studies	18% ± 3%	Explore
myofibroblast cell	7 studies	25% ± 7%	Explore
regulatory T cell	7 studies	19% ± 3%	Explore
gamma-delta T cell	7 studies	23% ± 14%	Explore
CD4-positive, alpha-beta T cell	6 studies	19% ± 4%	Explore
epithelial cell of proximal tubule	6 studies	20% ± 4%	Explore
abnormal cell	6 studies	21% ± 5%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	18% ± 2%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	17% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	22% ± 5%	Explore
kidney loop of Henle epithelial cell	5 studies	25% ± 4%	Explore
monocyte	5 studies	21% ± 8%	Explore
memory B cell	5 studies	17% ± 1%	Explore
endothelial cell of vascular tree	5 studies	19% ± 2%	Explore
type I pneumocyte	5 studies	29% ± 10%	Explore
dendritic cell	5 studies	40% ± 22%	Explore
goblet cell	5 studies	26% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	21% ± 8%	Explore
hematopoietic precursor cell	4 studies	31% ± 14%	Explore
leukocyte	4 studies	21% ± 6%	Explore
exhausted T cell	4 studies	25% ± 10%	Explore
progenitor cell	4 studies	24% ± 7%	Explore
retinal ganglion cell	4 studies	53% ± 28%	Explore
myeloid cell	4 studies	26% ± 10%	Explore
plasma cell	4 studies	26% ± 11%	Explore
neuron	4 studies	32% ± 17%	Explore
enteroendocrine cell	4 studies	27% ± 15%	Explore
pancreatic A cell	3 studies	36% ± 4%	Explore
type B pancreatic cell	3 studies	32% ± 1%	Explore
naive B cell	3 studies	19% ± 3%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	26% ± 3%	Explore
renal alpha-intercalated cell	3 studies	30% ± 2%	Explore
endothelial cell of artery	3 studies	19% ± 2%	Explore
enterocyte	3 studies	17% ± 1%	Explore
mesothelial cell	3 studies	33% ± 18%	Explore
neural crest cell	3 studies	21% ± 4%	Explore
innate lymphoid cell	3 studies	17% ± 1%	Explore
club cell	3 studies	30% ± 10%	Explore
capillary endothelial cell	3 studies	19% ± 2%	Explore
type II pneumocyte	3 studies	34% ± 11%	Explore
retina horizontal cell	3 studies	37% ± 13%	Explore
retinal cone cell	3 studies	46% ± 16%	Explore
intraepithelial lymphocyte	3 studies	21% ± 7%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	18% ± 1%	Explore
pancreatic ductal cell	3 studies	40% ± 11%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	35% ± 20%	Explore
intestinal crypt stem cell	3 studies	19% ± 2%	Explore
secretory cell	3 studies	33% ± 8%	Explore
hematopoietic stem cell	3 studies	17% ± 1%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	20% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	17% ± 2%	Explore
double negative thymocyte	3 studies	27% ± 11%	Explore
mucosal invariant T cell	3 studies	17% ± 2%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	11 studies	21% ± 6%	Explore
lung	9 studies	28% ± 9%	Explore
intestine	7 studies	21% ± 11%	Explore
kidney	6 studies	19% ± 3%	Explore
eye	5 studies	25% ± 10%	Explore
liver	4 studies	22% ± 10%	Explore
pancreas	3 studies	35% ± 3%	Explore
uterus	3 studies	28% ± 14%	Explore
brain	3 studies	20% ± 1%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	2792.42	258 / 258	100%	56.13	230 / 230
liver	100%	1788.52	226 / 226	100%	39.49	406 / 406
ovary	100%	2079.69	180 / 180	100%	37.77	430 / 430
thymus	100%	2937.11	653 / 653	100%	94.88	605 / 605
uterus	100%	3119.78	170 / 170	100%	56.95	459 / 459
skin	100%	2411.78	1808 / 1809	100%	60.34	472 / 472
brain	100%	2291.57	2639 / 2642	100%	67.47	705 / 705
prostate	100%	2431.11	245 / 245	100%	67.28	501 / 502
kidney	100%	3289.21	89 / 89	100%	67.30	899 / 901
esophagus	100%	2560.24	1445 / 1445	99%	25.31	182 / 183
pancreas	99%	1250.01	326 / 328	100%	47.66	178 / 178
stomach	100%	2204.16	359 / 359	99%	30.05	284 / 286
intestine	100%	2835.66	966 / 966	99%	35.85	523 / 527
lung	100%	2419.38	576 / 578	99%	44.13	1149 / 1155
breast	100%	2475.99	459 / 459	99%	46.32	1108 / 1118
bladder	100%	2786.71	21 / 21	99%	48.04	499 / 504
adipose	100%	2521.48	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	80.95	80 / 80
lymph node	0%	0	0 / 0	100%	74.40	29 / 29
muscle	100%	5790.35	803 / 803	0%	0	0 / 0
spleen	100%	2594.52	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	49.23	45 / 45
ureter	0%	0	0 / 0	100%	41.63	1 / 1
blood vessel	100%	2402.69	1334 / 1335	0%	0	0 / 0
heart	99%	4146.53	853 / 861	0%	0	0 / 0
peripheral blood	93%	1717.47	863 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0