SEPTIN9 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
T cell	33 studies	36% ± 14%	Explore
CD8-positive, alpha-beta T cell	32 studies	38% ± 17%	Explore
natural killer cell	31 studies	34% ± 12%	Explore
B cell	30 studies	34% ± 12%	Explore
CD4-positive, alpha-beta T cell	30 studies	43% ± 16%	Explore
pericyte	25 studies	29% ± 14%	Explore
regulatory T cell	24 studies	41% ± 16%	Explore
endothelial cell	21 studies	26% ± 9%	Explore
non-classical monocyte	20 studies	48% ± 19%	Explore
macrophage	20 studies	26% ± 10%	Explore
smooth muscle cell	19 studies	22% ± 5%	Explore
monocyte	18 studies	29% ± 10%	Explore
plasmacytoid dendritic cell	17 studies	54% ± 15%	Explore
classical monocyte	17 studies	31% ± 13%	Explore
conventional dendritic cell	16 studies	35% ± 17%	Explore
mature NK T cell	16 studies	37% ± 13%	Explore
naive B cell	16 studies	36% ± 12%	Explore
fibroblast	16 studies	23% ± 6%	Explore
endothelial cell of lymphatic vessel	15 studies	29% ± 9%	Explore
gamma-delta T cell	15 studies	39% ± 18%	Explore
memory B cell	15 studies	38% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	15 studies	41% ± 15%	Explore
basal cell	15 studies	35% ± 15%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	35% ± 13%	Explore
ciliated cell	14 studies	34% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	42% ± 16%	Explore
mast cell	12 studies	22% ± 6%	Explore
mucosal invariant T cell	12 studies	34% ± 14%	Explore
epithelial cell	12 studies	40% ± 21%	Explore
dendritic cell	12 studies	37% ± 21%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	47% ± 15%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	43% ± 12%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	47% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	38% ± 14%	Explore
myofibroblast cell	9 studies	26% ± 4%	Explore
myeloid cell	8 studies	38% ± 15%	Explore
club cell	7 studies	26% ± 10%	Explore
leukocyte	7 studies	29% ± 8%	Explore
T follicular helper cell	7 studies	45% ± 10%	Explore
precursor B cell	7 studies	53% ± 12%	Explore
plasma cell	6 studies	31% ± 11%	Explore
plasmablast	6 studies	39% ± 19%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	37% ± 14%	Explore
abnormal cell	6 studies	33% ± 13%	Explore
endothelial cell of artery	6 studies	20% ± 3%	Explore
lymphocyte	6 studies	38% ± 11%	Explore
connective tissue cell	6 studies	30% ± 9%	Explore
CD4-positive helper T cell	5 studies	27% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	33% ± 11%	Explore
innate lymphoid cell	5 studies	22% ± 2%	Explore
exhausted T cell	5 studies	48% ± 8%	Explore
pro-B cell	5 studies	63% ± 11%	Explore
T-helper 17 cell	5 studies	45% ± 16%	Explore
capillary endothelial cell	5 studies	17% ± 1%	Explore
type I pneumocyte	5 studies	25% ± 6%	Explore
type II pneumocyte	5 studies	22% ± 5%	Explore
astrocyte	5 studies	30% ± 11%	Explore
double negative thymocyte	5 studies	56% ± 14%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	35% ± 12%	Explore
respiratory goblet cell	4 studies	30% ± 12%	Explore
secretory cell	4 studies	26% ± 7%	Explore
mononuclear phagocyte	4 studies	37% ± 13%	Explore
hematopoietic precursor cell	4 studies	32% ± 15%	Explore
vein endothelial cell	4 studies	22% ± 6%	Explore
group 3 innate lymphoid cell	4 studies	53% ± 17%	Explore
immature B cell	4 studies	52% ± 19%	Explore
adipocyte	4 studies	26% ± 5%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	58% ± 9%	Explore
endothelial cell of vascular tree	4 studies	23% ± 8%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	40% ± 20%	Explore
enteroendocrine cell	4 studies	21% ± 5%	Explore
goblet cell	4 studies	35% ± 27%	Explore
alveolar macrophage	4 studies	42% ± 15%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	41% ± 16%	Explore
ionocyte	3 studies	40% ± 5%	Explore
cholangiocyte	3 studies	53% ± 30%	Explore
neural crest cell	3 studies	29% ± 4%	Explore
glutamatergic neuron	3 studies	23% ± 11%	Explore
extravillous trophoblast	3 studies	23% ± 7%	Explore
squamous epithelial cell	3 studies	38% ± 24%	Explore
retinal pigment epithelial cell	3 studies	34% ± 10%	Explore
glial cell	3 studies	31% ± 18%	Explore
germinal center B cell	3 studies	45% ± 6%	Explore
intermediate monocyte	3 studies	52% ± 26%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	21% ± 4%	Explore
muscle cell	3 studies	35% ± 5%	Explore
granulocyte	3 studies	22% ± 4%	Explore
transit amplifying cell	3 studies	38% ± 30%	Explore
brush cell	3 studies	22% ± 6%	Explore
hepatocyte	3 studies	66% ± 20%	Explore
mucus secreting cell	3 studies	35% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	17 studies	26% ± 7%	Explore
peripheral blood	15 studies	40% ± 12%	Explore
intestine	7 studies	24% ± 11%	Explore
breast	5 studies	19% ± 4%	Explore
kidney	4 studies	26% ± 7%	Explore
bone marrow	4 studies	33% ± 11%	Explore
liver	4 studies	33% ± 16%	Explore
brain	3 studies	25% ± 9%	Explore
lymph node	3 studies	46% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	16232.00	1445 / 1445	100%	99.61	183 / 183
ovary	100%	12307.25	180 / 180	100%	79.01	430 / 430
skin	100%	15152.46	1809 / 1809	100%	165.92	470 / 472
intestine	100%	20161.98	966 / 966	99%	83.89	524 / 527
stomach	100%	13557.53	359 / 359	99%	83.08	284 / 286
breast	100%	13149.89	459 / 459	99%	97.85	1109 / 1118
thymus	100%	9744.22	652 / 653	99%	96.52	601 / 605
uterus	100%	18654.18	170 / 170	99%	101.31	455 / 459
lung	100%	13124.85	577 / 578	99%	89.39	1146 / 1155
kidney	100%	10683.28	89 / 89	99%	76.61	891 / 901
bladder	100%	20634.10	21 / 21	99%	96.59	497 / 504
brain	98%	8675.25	2591 / 2642	100%	87.16	705 / 705
prostate	100%	16544.11	245 / 245	96%	68.79	484 / 502
liver	100%	8062.03	226 / 226	96%	54.25	388 / 406
adrenal gland	100%	14162.63	258 / 258	90%	50.49	207 / 230
pancreas	79%	3239.37	258 / 328	98%	93.79	175 / 178
adipose	100%	11449.05	1204 / 1204	0%	0	0 / 0
blood vessel	100%	13650.45	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	125.44	80 / 80
lymph node	0%	0	0 / 0	100%	174.70	29 / 29
spleen	100%	21974.46	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	84.93	45 / 45
ureter	0%	0	0 / 0	100%	25.69	1 / 1
muscle	99%	7176.97	792 / 803	0%	0	0 / 0
peripheral blood	98%	21625.81	914 / 929	0%	0	0 / 0
heart	98%	5689.31	843 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0061640	Biological process	cytoskeleton-dependent cytokinesis
GO_1902857	Biological process	positive regulation of non-motile cilium assembly
GO_0008104	Biological process	protein localization
GO_0032153	Cellular component	cell division site
GO_0005874	Cellular component	microtubule
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005930	Cellular component	axoneme
GO_0001725	Cellular component	stress fiber
GO_0015629	Cellular component	actin cytoskeleton
GO_0097730	Cellular component	non-motile cilium
GO_0015630	Cellular component	microtubule cytoskeleton
GO_0031105	Cellular component	septin complex
GO_0005737	Cellular component	cytoplasm
GO_0005940	Cellular component	septin ring
GO_0060090	Molecular function	molecular adaptor activity
GO_0045296	Molecular function	cadherin binding
GO_0005525	Molecular function	GTP binding
GO_0005515	Molecular function	protein binding
GO_0003924	Molecular function	GTPase activity

IV. Literature review

[source]

Gene name	SEPTIN9
Protein name	Septin 9 Septin-9 (MLL septin-like fusion protein MSF-A) (MLL septin-like fusion protein) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1) Septin-9 Septin 9 isoform 3 Septin 9 isoform 1 SEPT9 protein
Synonyms	MSF KIAA0991 SEPT9
Description	FUNCTION: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri. .
Accessions	ENST00000589070.1 A0A0S2Z5A5 ENST00000592951.5 [Q9UHD8-4] ENST00000591833.5 ENST00000586128.5 ENST00000589140.1 ENST00000590595.1 K7EQ08 A0A0S2Z5W9 A0A6Q8PHC2 K7EKN4 K7EJ51 K7ER34 ENST00000590917.5 Q9UHD8 ENST00000592481.6 K7ENQ5 ENST00000588958.6 ENST00000431235.6 [Q9UHD8-3] K7EPY1 K7ER52 K7EMW8 ENST00000588575.1 A0A0J9YWJ2 K7ER14 K7EQD7 Q1WWK5 ENST00000449803.6 [Q9UHD8-3] ENST00000427674.6 [Q9UHD8-3] K7EIE4 K7EL40 K7EN52 ENST00000633211.1 K7EK18 ENST00000591472.6 ENST00000586521.5 ENST00000590938.5 K7ENL0 K7EJZ2 ENST00000633557.1 ENST00000588690.6 [Q9UHD8-3] ENST00000591704.5 ENST00000591088.5 [Q9UHD8-4] ENST00000586433.5 ENST00000590059.5 ENST00000427180.5 [Q9UHD8-4] K7EJV0 ENST00000591198.5 [Q9UHD8-7] ENST00000591020.5 ENST00000591934.1 ENST00000423034.6 [Q9UHD8-5] ENST00000427177.6 [Q9UHD8-1] ENST00000329047.13 [Q9UHD8-2] ENST00000593189.6 ENST00000541152.6 [Q9UHD8-4] ENST00000585929.5 ENST00000585930.5 [Q9UHD8-9]

SEPTIN9 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review