Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 12 studies | 29% ± 14% | |
peripheral blood | 12 studies | 23% ± 5% | |
brain | 12 studies | 32% ± 16% | |
kidney | 7 studies | 23% ± 5% | |
intestine | 7 studies | 27% ± 13% | |
pancreas | 4 studies | 37% ± 13% | |
uterus | 4 studies | 31% ± 17% | |
lymph node | 4 studies | 20% ± 4% | |
breast | 4 studies | 20% ± 2% | |
liver | 4 studies | 35% ± 23% | |
eye | 3 studies | 22% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 865.21 | 2641 / 2642 | 100% | 52.74 | 705 / 705 |
ovary | 53% | 68.69 | 95 / 180 | 100% | 20.33 | 430 / 430 |
skin | 50% | 73.71 | 900 / 1809 | 100% | 35.17 | 472 / 472 |
prostate | 47% | 66.60 | 114 / 245 | 99% | 18.03 | 499 / 502 |
intestine | 47% | 99.43 | 450 / 966 | 99% | 19.51 | 523 / 527 |
breast | 44% | 92.80 | 204 / 459 | 97% | 14.60 | 1085 / 1118 |
esophagus | 39% | 69.22 | 568 / 1445 | 100% | 12.68 | 183 / 183 |
uterus | 34% | 41.25 | 57 / 170 | 100% | 23.63 | 458 / 459 |
bladder | 29% | 40.90 | 6 / 21 | 99% | 20.90 | 498 / 504 |
stomach | 13% | 21.18 | 45 / 359 | 99% | 17.59 | 284 / 286 |
lung | 9% | 10.46 | 54 / 578 | 99% | 17.94 | 1145 / 1155 |
thymus | 3% | 3.27 | 21 / 653 | 100% | 18.03 | 605 / 605 |
adrenal gland | 2% | 1.93 | 5 / 258 | 99% | 16.76 | 227 / 230 |
kidney | 1% | 0.85 | 1 / 89 | 99% | 12.83 | 894 / 901 |
eye | 0% | 0 | 0 / 0 | 100% | 24.56 | 80 / 80 |
liver | 0% | 0 | 0 / 226 | 100% | 22.32 | 406 / 406 |
lymph node | 0% | 0 | 0 / 0 | 100% | 23.41 | 29 / 29 |
tonsil | 0% | 0 | 0 / 0 | 100% | 18.88 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 22.95 | 1 / 1 |
pancreas | 0% | 0.29 | 1 / 328 | 99% | 14.14 | 177 / 178 |
heart | 18% | 22.86 | 159 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 15% | 19.29 | 201 / 1335 | 0% | 0 | 0 / 0 |
adipose | 10% | 11.56 | 117 / 1204 | 0% | 0 | 0 / 0 |
muscle | 8% | 7.73 | 63 / 803 | 0% | 0 | 0 / 0 |
spleen | 4% | 3.41 | 9 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0.24 | 2 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006366 | Biological process | transcription by RNA polymerase II |
GO_0042797 | Biological process | tRNA transcription by RNA polymerase III |
GO_0006360 | Biological process | transcription by RNA polymerase I |
GO_0005736 | Cellular component | RNA polymerase I complex |
GO_0005665 | Cellular component | RNA polymerase II, core complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005666 | Cellular component | RNA polymerase III complex |
GO_0001650 | Cellular component | fibrillar center |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0001055 | Molecular function | RNA polymerase II activity |
GO_0001056 | Molecular function | RNA polymerase III activity |
GO_0001054 | Molecular function | RNA polymerase I activity |
Gene name | POLR2F |
Protein name | RNA polymerase II, I and III subunit F DNA-directed RNA polymerases I, II, and III subunit RPABC2 (RNA polymerases I, II, and III subunit ABC2) (DNA-directed RNA polymerase II subunit F) (DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide) (RPABC14.4) (RPB14.4) (RPB6 homolog) (RPC15) DNA-directed RNA polymerases I, II, and III subunit RPABC2 (DNA-directed RNA polymerase II subunit F) (RPB6 homolog) |
Synonyms | POLRF |
Description | FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPABC2 is part of the clamp element and together with parts of POLR2A/RPB1 and POLR2B/RPB2 forms a pocket to which the POLR2D/RPB4-POLR2G/RPB7 subcomplex binds. . FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp element and together with parts of POLR2A/RPB1 and POLR2B/RPB2 forms a pocket to which the POLR2D/RPB4-POLR2G/RPB7 subcomplex binds. . FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp element and together with parts of POLR2A/RPB1 and POLR2B/RPB2 forms a pocket to which the POLR2D/RPB4-POLR2G/RPB7 subcomplex binds. . FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp element and together with parts of POLR2A/RPB1 and POLR2B/RPB2 forms a pocket to which the POLR2D/RPB4-POLR2G/RPB7 subcomplex binds. . FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp element and together with parts of POLR2A/RPB1 and POLR2B/RPB2 forms a pocket to which the POLR2D/RPB4-POLR2G/RPB7 subcomplex binds. . |
Accessions | ENST00000405557.5 P61218 ENST00000606538.5 B0QYL9 H0Y439 U3KQB0 ENST00000407936.5 ENST00000488684.5 U3KQS8 ENST00000333418.4 ENST00000492213.5 U3KQQ7 ENST00000460648.5 F8WC47 ENST00000427034.1 H0Y2U7 ENST00000442738.7 B0QYL8 ENST00000443002.5 U3KPY1 ENST00000483713.5 U3KPV3 ENST00000470701.1 |