NUTF2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	19 studies	26% ± 10%	Explore
B cell	16 studies	25% ± 8%	Explore
CD4-positive, alpha-beta T cell	16 studies	31% ± 16%	Explore
endothelial cell	16 studies	28% ± 11%	Explore
regulatory T cell	16 studies	28% ± 10%	Explore
macrophage	15 studies	24% ± 9%	Explore
conventional dendritic cell	14 studies	31% ± 16%	Explore
CD8-positive, alpha-beta T cell	14 studies	32% ± 12%	Explore
fibroblast	14 studies	27% ± 9%	Explore
T cell	13 studies	27% ± 7%	Explore
pericyte	12 studies	29% ± 11%	Explore
gamma-delta T cell	12 studies	25% ± 14%	Explore
naive B cell	12 studies	20% ± 3%	Explore
smooth muscle cell	11 studies	28% ± 8%	Explore
memory B cell	10 studies	23% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	27% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	24% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	24% ± 6%	Explore
non-classical monocyte	10 studies	29% ± 12%	Explore
epithelial cell	10 studies	39% ± 19%	Explore
connective tissue cell	9 studies	34% ± 9%	Explore
mucosal invariant T cell	9 studies	22% ± 4%	Explore
basal cell	9 studies	29% ± 14%	Explore
plasmacytoid dendritic cell	9 studies	25% ± 8%	Explore
platelet	8 studies	30% ± 8%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	28% ± 7%	Explore
endothelial cell of lymphatic vessel	8 studies	28% ± 9%	Explore
plasmablast	7 studies	38% ± 23%	Explore
classical monocyte	7 studies	25% ± 9%	Explore
mature NK T cell	7 studies	23% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	21% ± 4%	Explore
myofibroblast cell	7 studies	34% ± 5%	Explore
monocyte	7 studies	20% ± 5%	Explore
dendritic cell	7 studies	32% ± 19%	Explore
hematopoietic stem cell	7 studies	32% ± 10%	Explore
precursor B cell	7 studies	37% ± 15%	Explore
myeloid cell	7 studies	24% ± 7%	Explore
ciliated cell	7 studies	38% ± 10%	Explore
endothelial cell of vascular tree	7 studies	20% ± 3%	Explore
progenitor cell	6 studies	28% ± 7%	Explore
neuron	6 studies	32% ± 17%	Explore
erythrocyte	6 studies	35% ± 20%	Explore
abnormal cell	6 studies	28% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	28% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	24% ± 3%	Explore
mesothelial cell	5 studies	34% ± 15%	Explore
vein endothelial cell	5 studies	24% ± 9%	Explore
erythroblast	5 studies	48% ± 23%	Explore
pro-B cell	5 studies	40% ± 13%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	36% ± 13%	Explore
hematopoietic precursor cell	4 studies	47% ± 6%	Explore
plasma cell	4 studies	37% ± 16%	Explore
megakaryocyte	4 studies	32% ± 9%	Explore
T follicular helper cell	4 studies	25% ± 3%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	36% ± 6%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	23% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	32% ± 8%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	48% ± 26%	Explore
innate lymphoid cell	4 studies	23% ± 4%	Explore
enteroendocrine cell	4 studies	29% ± 13%	Explore
secretory cell	4 studies	24% ± 13%	Explore
pancreatic A cell	3 studies	39% ± 17%	Explore
endothelial cell of artery	3 studies	24% ± 8%	Explore
leukocyte	3 studies	25% ± 6%	Explore
neural crest cell	3 studies	34% ± 7%	Explore
common myeloid progenitor	3 studies	33% ± 19%	Explore
lymphocyte	3 studies	28% ± 7%	Explore
capillary endothelial cell	3 studies	29% ± 9%	Explore
immature B cell	3 studies	28% ± 5%	Explore
type I pneumocyte	3 studies	33% ± 5%	Explore
type II pneumocyte	3 studies	30% ± 15%	Explore
germinal center B cell	3 studies	29% ± 6%	Explore
exhausted T cell	3 studies	31% ± 7%	Explore
intermediate monocyte	3 studies	30% ± 10%	Explore
GABAergic neuron	3 studies	21% ± 5%	Explore
glutamatergic neuron	3 studies	26% ± 7%	Explore
goblet cell	3 studies	26% ± 15%	Explore
intestinal crypt stem cell	3 studies	23% ± 1%	Explore
group 3 innate lymphoid cell	3 studies	40% ± 10%	Explore
transit amplifying cell	3 studies	22% ± 4%	Explore
T-helper 17 cell	3 studies	33% ± 23%	Explore
double negative thymocyte	3 studies	37% ± 18%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	12 studies	24% ± 6%	Explore
lung	8 studies	30% ± 11%	Explore
intestine	5 studies	28% ± 14%	Explore
bone marrow	5 studies	22% ± 7%	Explore
brain	5 studies	20% ± 4%	Explore
kidney	4 studies	24% ± 5%	Explore
placenta	3 studies	28% ± 13%	Explore
liver	3 studies	36% ± 26%	Explore
lymph node	3 studies	24% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	3156.53	258 / 258	100%	79.61	230 / 230
bladder	100%	3676.33	21 / 21	100%	116.38	504 / 504
brain	100%	4193.81	2642 / 2642	100%	91.23	705 / 705
esophagus	100%	3485.03	1445 / 1445	100%	81.59	183 / 183
intestine	100%	3264.60	966 / 966	100%	108.57	527 / 527
ovary	100%	2678.33	180 / 180	100%	126.51	430 / 430
prostate	100%	3118.18	245 / 245	100%	71.64	502 / 502
skin	100%	4123.39	1809 / 1809	100%	95.37	472 / 472
stomach	100%	2332.63	359 / 359	100%	102.50	286 / 286
thymus	100%	2727.56	653 / 653	100%	70.84	605 / 605
uterus	100%	3497.51	170 / 170	100%	114.05	459 / 459
lung	100%	3325.21	578 / 578	100%	86.46	1154 / 1155
kidney	100%	2778.58	89 / 89	100%	69.43	900 / 901
breast	100%	3161.72	459 / 459	99%	84.96	1111 / 1118
liver	100%	1682.15	225 / 226	100%	52.70	405 / 406
pancreas	100%	1960.95	327 / 328	99%	79.53	177 / 178
adipose	100%	3303.45	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	83.05	80 / 80
lymph node	0%	0	0 / 0	100%	121.93	29 / 29
muscle	100%	3200.25	803 / 803	0%	0	0 / 0
spleen	100%	2603.71	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	73.86	45 / 45
ureter	0%	0	0 / 0	100%	143.88	1 / 1
blood vessel	100%	4551.44	1334 / 1335	0%	0	0 / 0
heart	99%	2634.15	850 / 861	0%	0	0 / 0
peripheral blood	94%	2207.31	877 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0090204	Biological process	protein localization to nuclear pore
GO_0006606	Biological process	protein import into nucleus
GO_0006611	Biological process	protein export from nucleus
GO_0051028	Biological process	mRNA transport
GO_0044613	Cellular component	nuclear pore central transport channel
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0031965	Cellular component	nuclear membrane
GO_0005637	Cellular component	nuclear inner membrane
GO_0005640	Cellular component	nuclear outer membrane
GO_0017056	Molecular function	structural constituent of nuclear pore
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0031267	Molecular function	small GTPase binding
GO_0061608	Molecular function	nuclear import signal receptor activity

IV. Literature review

[source]

Gene name	NUTF2
Protein name	Nuclear transport factor 2 (NTF-2) Nuclear transport factor 2 Nuclear transport factor 2 (NTF-2) (Placental protein 15) (PP15) NTF2-related export protein
Synonyms	NTF2
Description	FUNCTION: Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import. . FUNCTION: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs. .; FUNCTION: Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import. . FUNCTION: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs. .; FUNCTION: Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import. . FUNCTION: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs. .; FUNCTION: Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import. . FUNCTION: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs. .; FUNCTION: Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import. . FUNCTION: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs. .; FUNCTION: Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import. .
Accessions	ENST00000700614.1 ENST00000700611.1 ENST00000568396.2 ENST00000700615.1 ENST00000569436.7 ENST00000568390.5 ENST00000219169.9 A0A8V8TR28 A0A8V8TPY3 ENST00000700612.1 ENST00000700610.1 A0A8V8TRD3 ENST00000700613.1 P61970 H3BRV9 ENST00000570026.2 A0A8V8TR25 ENST00000567105.5 B4DEQ2 ENST00000568233.6

NUTF2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review