MTCH1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	39 studies	38% ± 16%	Explore
endothelial cell	37 studies	33% ± 12%	Explore
macrophage	31 studies	26% ± 9%	Explore
pericyte	29 studies	33% ± 14%	Explore
natural killer cell	25 studies	22% ± 7%	Explore
smooth muscle cell	25 studies	33% ± 12%	Explore
classical monocyte	20 studies	27% ± 11%	Explore
CD8-positive, alpha-beta T cell	20 studies	23% ± 7%	Explore
CD4-positive, alpha-beta T cell	19 studies	22% ± 6%	Explore
conventional dendritic cell	18 studies	27% ± 14%	Explore
basal cell	18 studies	36% ± 16%	Explore
connective tissue cell	18 studies	40% ± 15%	Explore
T cell	17 studies	23% ± 6%	Explore
endothelial cell of lymphatic vessel	17 studies	34% ± 12%	Explore
non-classical monocyte	17 studies	31% ± 14%	Explore
epithelial cell	17 studies	39% ± 20%	Explore
B cell	16 studies	23% ± 7%	Explore
ciliated cell	15 studies	36% ± 14%	Explore
astrocyte	15 studies	28% ± 11%	Explore
monocyte	14 studies	27% ± 7%	Explore
myofibroblast cell	14 studies	38% ± 13%	Explore
regulatory T cell	14 studies	23% ± 4%	Explore
capillary endothelial cell	13 studies	27% ± 9%	Explore
oligodendrocyte	13 studies	30% ± 11%	Explore
dendritic cell	12 studies	31% ± 18%	Explore
naive B cell	12 studies	20% ± 4%	Explore
vein endothelial cell	12 studies	29% ± 13%	Explore
memory B cell	12 studies	19% ± 3%	Explore
secretory cell	11 studies	29% ± 12%	Explore
endothelial cell of vascular tree	11 studies	28% ± 5%	Explore
myeloid cell	11 studies	29% ± 12%	Explore
type I pneumocyte	10 studies	38% ± 12%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	24% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	23% ± 6%	Explore
mature NK T cell	10 studies	19% ± 3%	Explore
abnormal cell	10 studies	33% ± 13%	Explore
endothelial cell of artery	10 studies	30% ± 8%	Explore
glutamatergic neuron	10 studies	39% ± 19%	Explore
gamma-delta T cell	10 studies	27% ± 15%	Explore
type II pneumocyte	9 studies	34% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	24% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	23% ± 5%	Explore
plasmacytoid dendritic cell	9 studies	25% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	22% ± 3%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	22% ± 3%	Explore
neuron	8 studies	44% ± 16%	Explore
goblet cell	8 studies	24% ± 11%	Explore
microglial cell	8 studies	27% ± 6%	Explore
leukocyte	7 studies	26% ± 6%	Explore
GABAergic neuron	7 studies	36% ± 18%	Explore
club cell	6 studies	32% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	24% ± 9%	Explore
mesothelial cell	6 studies	42% ± 18%	Explore
mucosal invariant T cell	6 studies	20% ± 2%	Explore
cardiac muscle cell	6 studies	22% ± 6%	Explore
oligodendrocyte precursor cell	6 studies	29% ± 8%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	24% ± 7%	Explore
mononuclear phagocyte	5 studies	30% ± 17%	Explore
kidney loop of Henle epithelial cell	5 studies	27% ± 2%	Explore
progenitor cell	5 studies	34% ± 18%	Explore
epithelial cell of proximal tubule	5 studies	22% ± 5%	Explore
enteroendocrine cell	5 studies	37% ± 16%	Explore
lymphocyte	5 studies	28% ± 11%	Explore
precursor B cell	5 studies	26% ± 8%	Explore
innate lymphoid cell	5 studies	23% ± 7%	Explore
T follicular helper cell	5 studies	21% ± 4%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	28% ± 9%	Explore
hematopoietic precursor cell	4 studies	30% ± 15%	Explore
respiratory goblet cell	4 studies	32% ± 17%	Explore
pancreatic A cell	4 studies	59% ± 12%	Explore
type B pancreatic cell	4 studies	53% ± 17%	Explore
exhausted T cell	4 studies	25% ± 7%	Explore
enterocyte	4 studies	17% ± 2%	Explore
retinal ganglion cell	4 studies	81% ± 19%	Explore
pro-B cell	4 studies	27% ± 4%	Explore
amacrine cell	4 studies	44% ± 18%	Explore
retina horizontal cell	4 studies	42% ± 15%	Explore
adventitial cell	4 studies	40% ± 4%	Explore
Mueller cell	4 studies	35% ± 6%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	25% ± 7%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	23% ± 5%	Explore
transit amplifying cell	4 studies	28% ± 12%	Explore
interneuron	4 studies	38% ± 18%	Explore
duct epithelial cell	3 studies	18% ± 4%	Explore
ionocyte	3 studies	25% ± 4%	Explore
squamous epithelial cell	3 studies	41% ± 23%	Explore
pancreatic D cell	3 studies	57% ± 18%	Explore
glomerular endothelial cell	3 studies	31% ± 7%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	35% ± 4%	Explore
intestinal crypt stem cell	3 studies	22% ± 5%	Explore
neural crest cell	3 studies	36% ± 7%	Explore
GABAergic amacrine cell	3 studies	42% ± 12%	Explore
placental villous trophoblast	3 studies	32% ± 9%	Explore
immature B cell	3 studies	22% ± 4%	Explore
retinal pigment epithelial cell	3 studies	44% ± 20%	Explore
retinal rod cell	3 studies	20% ± 3%	Explore
serous secreting cell	3 studies	24% ± 2%	Explore
tissue-resident macrophage	3 studies	27% ± 11%	Explore
adipocyte	3 studies	28% ± 12%	Explore
luminal cell of prostate epithelium	3 studies	23% ± 9%	Explore
muscle cell	3 studies	39% ± 16%	Explore
pancreatic ductal cell	3 studies	55% ± 8%	Explore
glial cell	3 studies	36% ± 21%	Explore
alveolar macrophage	3 studies	27% ± 8%	Explore
group 3 innate lymphoid cell	3 studies	29% ± 11%	Explore
melanocyte	3 studies	35% ± 8%	Explore
progenitor cell of mammary luminal epithelium	3 studies	33% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	17 studies	32% ± 12%	Explore
brain	14 studies	33% ± 16%	Explore
peripheral blood	12 studies	27% ± 10%	Explore
intestine	9 studies	27% ± 14%	Explore
kidney	7 studies	24% ± 5%	Explore
eye	7 studies	35% ± 9%	Explore
lymph node	5 studies	25% ± 9%	Explore
pancreas	4 studies	52% ± 17%	Explore
bone marrow	4 studies	21% ± 3%	Explore
uterus	4 studies	41% ± 14%	Explore
breast	4 studies	29% ± 2%	Explore
liver	4 studies	31% ± 20%	Explore
placenta	3 studies	34% ± 7%	Explore
heart	3 studies	21% ± 5%	Explore
adrenal gland	3 studies	28% ± 8%	Explore
prostate	3 studies	24% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	12680.11	1445 / 1445	100%	139.40	183 / 183
lung	100%	19179.87	578 / 578	100%	212.57	1155 / 1155
ovary	100%	15991.94	180 / 180	100%	251.14	430 / 430
prostate	100%	18318.18	245 / 245	100%	273.97	502 / 502
stomach	100%	11487.32	359 / 359	100%	166.02	286 / 286
thymus	100%	37447.65	653 / 653	100%	521.67	605 / 605
brain	100%	19792.63	2640 / 2642	100%	362.58	705 / 705
uterus	100%	14438.11	170 / 170	100%	250.33	458 / 459
pancreas	100%	8605.11	327 / 328	100%	203.33	178 / 178
breast	100%	13778.71	459 / 459	100%	217.10	1114 / 1118
skin	100%	14817.61	1808 / 1809	100%	268.58	470 / 472
kidney	100%	13870.39	89 / 89	99%	198.33	896 / 901
intestine	100%	13045.08	966 / 966	99%	191.76	524 / 527
bladder	100%	14989.67	21 / 21	99%	214.59	501 / 504
adrenal gland	100%	24369.21	258 / 258	99%	324.00	228 / 230
liver	100%	5775.45	225 / 226	99%	137.26	402 / 406
adipose	100%	13907.48	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	245.18	80 / 80
lymph node	0%	0	0 / 0	100%	153.67	29 / 29
spleen	100%	13945.15	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	187.98	45 / 45
ureter	0%	0	0 / 0	100%	168.36	1 / 1
blood vessel	100%	13711.30	1334 / 1335	0%	0	0 / 0
heart	99%	15908.17	853 / 861	0%	0	0 / 0
muscle	99%	7229.85	795 / 803	0%	0	0 / 0
peripheral blood	96%	7486.56	889 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006915	Biological process	apoptotic process
GO_0009966	Biological process	regulation of signal transduction
GO_0006919	Biological process	activation of cysteine-type endopeptidase activity involved in apoptotic process
GO_0043065	Biological process	positive regulation of apoptotic process
GO_0045161	Biological process	neuronal ion channel clustering
GO_0045040	Biological process	protein insertion into mitochondrial outer membrane
GO_0005741	Cellular component	mitochondrial outer membrane
GO_0016020	Cellular component	membrane
GO_0005739	Cellular component	mitochondrion
GO_0032977	Molecular function	membrane insertase activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	MTCH1
Protein name	Mitochondrial carrier 1 (Mitochondrial carrier homolog 1 (C. elegans), isoform CRA_a) Mitochondrial carrier 1 MTCH1 protein Mitochondrial carrier homolog 1 (Presenilin-associated protein)
Synonyms	PSAP CGI-64 UNQ1871/PRO4314 hCG_15365
Description	FUNCTION: Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane . Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins (By similarity). Does not mediate insertion of beta-barrel transmembrane proteins (By similarity). May play a role in apoptosis . .
Accessions	ENST00000695054.1 H7C196 A0A8Q3WKA3 A0A8Q3WKC1 Q9NZJ7 ENST00000695072.1 A4FVA6 ENST00000695071.1 ENST00000695051.1 A0A8Q3SHP9 A0A8Q3WKF6 ENST00000373616.9 [Q9NZJ7-2] H0Y8C3 ENST00000695050.1 ENST00000695060.1 A0A8Q3SHK9 ENST00000695053.1 ENST00000695049.1 Q8IW90 ENST00000695055.1 ENST00000418541.6 ENST00000695074.1 A0A8Q3WLF0 A0A8Q3SHJ3 A0A8Q3WLQ4 ENST00000695067.1 ENST00000695068.1 A0A8Q3SHJ6 A0A8Q3SHR5 ENST00000460219.3 A0A8Q3WKA4 A0A8Q3WLQ9 ENST00000695046.1 ENST00000695065.1 ENST00000373627.10 [Q9NZJ7-1] A0A8Q3SHP5 ENST00000695062.1 ENST00000695045.1 ENST00000695044.1 A0A8Q3SHP2 ENST00000695075.1 ENST00000695063.1 ENST00000695073.1 ENST00000695069.1 A0A8Q3WKU8 A0A8Q3WKA5 ENST00000695047.1 A0A8Q3WKC8 ENST00000695070.1

MTCH1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review