MAP4 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	47 studies	42% ± 15%	Explore
fibroblast	40 studies	35% ± 16%	Explore
pericyte	35 studies	38% ± 17%	Explore
smooth muscle cell	30 studies	36% ± 14%	Explore
astrocyte	21 studies	45% ± 19%	Explore
macrophage	19 studies	27% ± 12%	Explore
endothelial cell of lymphatic vessel	15 studies	38% ± 13%	Explore
oligodendrocyte	15 studies	41% ± 15%	Explore
capillary endothelial cell	15 studies	30% ± 10%	Explore
natural killer cell	14 studies	21% ± 5%	Explore
endothelial cell of artery	14 studies	41% ± 13%	Explore
B cell	13 studies	21% ± 6%	Explore
oligodendrocyte precursor cell	13 studies	34% ± 15%	Explore
connective tissue cell	12 studies	30% ± 13%	Explore
myofibroblast cell	12 studies	35% ± 13%	Explore
microglial cell	12 studies	35% ± 13%	Explore
ciliated cell	12 studies	31% ± 13%	Explore
vein endothelial cell	11 studies	30% ± 15%	Explore
dendritic cell	11 studies	32% ± 11%	Explore
T cell	10 studies	24% ± 6%	Explore
type I pneumocyte	10 studies	40% ± 13%	Explore
GABAergic neuron	10 studies	43% ± 18%	Explore
glutamatergic neuron	10 studies	45% ± 21%	Explore
epithelial cell	10 studies	41% ± 20%	Explore
adipocyte	10 studies	56% ± 11%	Explore
gamma-delta T cell	10 studies	21% ± 4%	Explore
neuron	9 studies	45% ± 17%	Explore
retinal cone cell	9 studies	78% ± 14%	Explore
basal cell	9 studies	33% ± 19%	Explore
endothelial cell of vascular tree	9 studies	36% ± 19%	Explore
regulatory T cell	9 studies	19% ± 1%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	20% ± 3%	Explore
CD4-positive, alpha-beta T cell	8 studies	21% ± 4%	Explore
mature NK T cell	8 studies	18% ± 6%	Explore
myeloid cell	8 studies	32% ± 11%	Explore
mast cell	7 studies	23% ± 13%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	21% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	18% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	21% ± 3%	Explore
retinal ganglion cell	7 studies	73% ± 24%	Explore
retinal rod cell	7 studies	25% ± 6%	Explore
mesothelial cell	7 studies	42% ± 8%	Explore
CD8-positive, alpha-beta T cell	7 studies	23% ± 3%	Explore
interneuron	6 studies	47% ± 19%	Explore
cardiac muscle cell	6 studies	73% ± 20%	Explore
Mueller cell	6 studies	34% ± 2%	Explore
type II pneumocyte	6 studies	27% ± 5%	Explore
non-classical monocyte	5 studies	26% ± 8%	Explore
conventional dendritic cell	5 studies	23% ± 11%	Explore
abnormal cell	5 studies	40% ± 16%	Explore
retinal bipolar neuron	5 studies	74% ± 10%	Explore
glial cell	5 studies	36% ± 15%	Explore
OFF-bipolar cell	5 studies	68% ± 19%	Explore
ON-bipolar cell	5 studies	66% ± 20%	Explore
retina horizontal cell	5 studies	27% ± 6%	Explore
adventitial cell	5 studies	27% ± 11%	Explore
lymphocyte	5 studies	39% ± 15%	Explore
memory B cell	5 studies	19% ± 2%	Explore
goblet cell	5 studies	31% ± 23%	Explore
club cell	5 studies	28% ± 5%	Explore
plasmacytoid dendritic cell	5 studies	22% ± 7%	Explore
leukocyte	4 studies	24% ± 7%	Explore
naive B cell	4 studies	18% ± 1%	Explore
granule cell	4 studies	30% ± 9%	Explore
plasma cell	4 studies	36% ± 6%	Explore
amacrine cell	4 studies	37% ± 10%	Explore
retinal pigment epithelial cell	4 studies	39% ± 21%	Explore
muscle cell	4 studies	53% ± 16%	Explore
alveolar macrophage	4 studies	39% ± 14%	Explore
monocyte	4 studies	36% ± 8%	Explore
mucosal invariant T cell	4 studies	22% ± 7%	Explore
renal principal cell	4 studies	39% ± 13%	Explore
ionocyte	3 studies	26% ± 7%	Explore
hepatic stellate cell	3 studies	45% ± 21%	Explore
glomerular endothelial cell	3 studies	28% ± 6%	Explore
progenitor cell	3 studies	31% ± 9%	Explore
renal alpha-intercalated cell	3 studies	25% ± 9%	Explore
renal beta-intercalated cell	3 studies	39% ± 13%	Explore
GABAergic interneuron	3 studies	35% ± 7%	Explore
mononuclear phagocyte	3 studies	30% ± 11%	Explore
rod bipolar cell	3 studies	82% ± 3%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	19% ± 3%	Explore
myoepithelial cell	3 studies	38% ± 17%	Explore
cholangiocyte	3 studies	61% ± 15%	Explore
hepatocyte	3 studies	55% ± 19%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	19% ± 5%	Explore
ependymal cell	3 studies	69% ± 12%	Explore
chondrocyte	3 studies	32% ± 9%	Explore
Schwann cell	3 studies	57% ± 20%	Explore
melanocyte	3 studies	32% ± 17%	Explore
transit amplifying cell	3 studies	44% ± 32%	Explore
double negative thymocyte	3 studies	22% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	21% ± 5%	Explore
kidney loop of Henle epithelial cell	3 studies	29% ± 7%	Explore
mural cell	3 studies	53% ± 8%	Explore
mucus secreting cell	3 studies	30% ± 4%	Explore
enteroendocrine cell	3 studies	22% ± 4%	Explore
secretory cell	3 studies	35% ± 10%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	18 studies	40% ± 18%	Explore
lung	12 studies	28% ± 8%	Explore
eye	10 studies	41% ± 14%	Explore
heart	6 studies	49% ± 18%	Explore
intestine	5 studies	23% ± 7%	Explore
kidney	5 studies	29% ± 8%	Explore
peripheral blood	4 studies	23% ± 8%	Explore
adipose	4 studies	43% ± 19%	Explore
uterus	3 studies	33% ± 9%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	28748.37	1445 / 1445	100%	59.96	183 / 183
brain	100%	48517.41	2641 / 2642	100%	174.91	705 / 705
skin	100%	28776.34	1808 / 1809	100%	110.61	472 / 472
uterus	100%	25416.59	170 / 170	100%	61.21	458 / 459
breast	100%	23093.39	459 / 459	100%	73.14	1115 / 1118
prostate	100%	21524.35	244 / 245	100%	60.83	502 / 502
kidney	100%	17204.38	89 / 89	100%	66.73	897 / 901
intestine	100%	31187.74	964 / 966	100%	55.74	525 / 527
bladder	100%	31015.81	21 / 21	99%	56.38	500 / 504
thymus	99%	15187.01	648 / 653	100%	61.00	604 / 605
ovary	100%	19404.27	180 / 180	99%	55.80	424 / 430
lung	100%	24130.54	576 / 578	99%	51.92	1139 / 1155
stomach	95%	17564.37	340 / 359	100%	57.14	285 / 286
adrenal gland	92%	11636.65	237 / 258	95%	44.72	218 / 230
pancreas	77%	7949.89	253 / 328	99%	65.49	177 / 178
liver	55%	5223.38	124 / 226	95%	35.17	387 / 406
adipose	100%	27892.84	1204 / 1204	0%	0	0 / 0
blood vessel	100%	43315.23	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	93.43	80 / 80
lymph node	0%	0	0 / 0	100%	47.06	29 / 29
muscle	100%	97952.71	803 / 803	0%	0	0 / 0
spleen	100%	13669.59	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	63.51	45 / 45
ureter	0%	0	0 / 0	100%	28.33	1 / 1
heart	99%	47672.33	853 / 861	0%	0	0 / 0
peripheral blood	22%	4263.91	200 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0