M6PR report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
macrophage	33 studies	37% ± 11%	Explore
natural killer cell	30 studies	27% ± 8%	Explore
conventional dendritic cell	27 studies	39% ± 15%	Explore
CD4-positive, alpha-beta T cell	27 studies	25% ± 6%	Explore
CD8-positive, alpha-beta T cell	26 studies	26% ± 8%	Explore
non-classical monocyte	23 studies	45% ± 13%	Explore
classical monocyte	23 studies	30% ± 11%	Explore
regulatory T cell	21 studies	28% ± 9%	Explore
plasmacytoid dendritic cell	19 studies	39% ± 12%	Explore
T cell	18 studies	24% ± 7%	Explore
monocyte	18 studies	31% ± 10%	Explore
naive B cell	18 studies	20% ± 4%	Explore
B cell	17 studies	22% ± 5%	Explore
memory B cell	17 studies	22% ± 6%	Explore
mast cell	15 studies	34% ± 11%	Explore
mature NK T cell	15 studies	27% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	32% ± 9%	Explore
dendritic cell	13 studies	39% ± 20%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	24% ± 7%	Explore
gamma-delta T cell	13 studies	28% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	27% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	29% ± 8%	Explore
myeloid cell	12 studies	37% ± 16%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	28% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	28% ± 11%	Explore
endothelial cell	10 studies	22% ± 7%	Explore
mucosal invariant T cell	9 studies	29% ± 6%	Explore
alveolar macrophage	8 studies	35% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	27% ± 9%	Explore
leukocyte	7 studies	26% ± 8%	Explore
epithelial cell	7 studies	33% ± 17%	Explore
T follicular helper cell	7 studies	26% ± 5%	Explore
hematopoietic precursor cell	6 studies	35% ± 6%	Explore
basal cell	6 studies	31% ± 16%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	30% ± 14%	Explore
fibroblast	6 studies	24% ± 7%	Explore
pericyte	6 studies	21% ± 4%	Explore
innate lymphoid cell	6 studies	27% ± 6%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	28% ± 10%	Explore
plasma cell	5 studies	25% ± 8%	Explore
mononuclear phagocyte	5 studies	39% ± 16%	Explore
microglial cell	5 studies	27% ± 10%	Explore
ciliated cell	5 studies	32% ± 8%	Explore
abnormal cell	5 studies	21% ± 4%	Explore
plasmablast	4 studies	47% ± 21%	Explore
exhausted T cell	4 studies	36% ± 8%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	37% ± 11%	Explore
T-helper 17 cell	4 studies	25% ± 6%	Explore
hematopoietic stem cell	4 studies	26% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	30% ± 10%	Explore
platelet	3 studies	19% ± 2%	Explore
common myeloid progenitor	3 studies	31% ± 16%	Explore
lymphocyte	3 studies	24% ± 5%	Explore
megakaryocyte	3 studies	35% ± 11%	Explore
myofibroblast cell	3 studies	16% ± 1%	Explore
smooth muscle cell	3 studies	21% ± 3%	Explore
immature B cell	3 studies	20% ± 3%	Explore
pro-B cell	3 studies	21% ± 3%	Explore
retina horizontal cell	3 studies	23% ± 7%	Explore
tissue-resident macrophage	3 studies	29% ± 8%	Explore
intermediate monocyte	3 studies	50% ± 15%	Explore
type I pneumocyte	3 studies	24% ± 7%	Explore
GABAergic neuron	3 studies	32% ± 7%	Explore
glutamatergic neuron	3 studies	38% ± 12%	Explore
connective tissue cell	3 studies	25% ± 7%	Explore
granulocyte monocyte progenitor cell	3 studies	30% ± 4%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	40% ± 25%	Explore
group 3 innate lymphoid cell	3 studies	31% ± 9%	Explore
T-helper 1 cell	3 studies	31% ± 9%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	33% ± 13%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	29% ± 14%	Explore
double negative thymocyte	3 studies	34% ± 4%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	16 studies	28% ± 7%	Explore
lung	14 studies	23% ± 9%	Explore
brain	6 studies	27% ± 10%	Explore
liver	5 studies	25% ± 10%	Explore
bone marrow	4 studies	26% ± 6%	Explore
lymph node	4 studies	26% ± 5%	Explore
intestine	3 studies	24% ± 9%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	3851.78	578 / 578	99%	75.69	1143 / 1155
stomach	100%	2284.19	359 / 359	99%	56.50	283 / 286
esophagus	100%	2629.04	1445 / 1445	99%	49.01	181 / 183
intestine	100%	2871.26	965 / 966	99%	62.82	521 / 527
skin	100%	3147.39	1809 / 1809	99%	97.70	466 / 472
ovary	100%	2610.39	180 / 180	99%	55.26	424 / 430
pancreas	100%	1824.80	327 / 328	98%	54.34	175 / 178
breast	100%	2996.87	459 / 459	98%	72.55	1094 / 1118
bladder	100%	2987.57	21 / 21	96%	61.15	484 / 504
kidney	100%	2151.94	89 / 89	96%	65.73	862 / 901
brain	96%	1477.46	2544 / 2642	99%	51.33	697 / 705
thymus	100%	3072.99	653 / 653	95%	64.50	573 / 605
uterus	100%	2933.41	170 / 170	94%	53.54	433 / 459
prostate	100%	2215.61	245 / 245	94%	40.55	472 / 502
adrenal gland	100%	3313.88	258 / 258	87%	41.86	199 / 230
liver	96%	1227.29	217 / 226	78%	24.54	316 / 406
adipose	100%	3147.28	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2832.84	1335 / 1335	0%	0	0 / 0
spleen	100%	4376.70	241 / 241	0%	0	0 / 0
muscle	100%	1764.35	800 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	99%	57.83	79 / 80
peripheral blood	98%	3914.08	914 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	75.02	28 / 29
tonsil	0%	0	0 / 0	96%	66.66	43 / 45
heart	95%	2158.87	822 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1