ITM2A report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	40 studies	50% ± 19%	Explore
CD8-positive, alpha-beta T cell	34 studies	39% ± 16%	Explore
CD4-positive, alpha-beta T cell	31 studies	43% ± 19%	Explore
natural killer cell	30 studies	27% ± 11%	Explore
T cell	26 studies	36% ± 15%	Explore
regulatory T cell	25 studies	43% ± 14%	Explore
mature NK T cell	18 studies	31% ± 10%	Explore
mast cell	16 studies	30% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	16 studies	34% ± 10%	Explore
fibroblast	16 studies	42% ± 22%	Explore
capillary endothelial cell	15 studies	55% ± 13%	Explore
gamma-delta T cell	15 studies	36% ± 12%	Explore
vein endothelial cell	13 studies	48% ± 16%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	34% ± 14%	Explore
endothelial cell of artery	12 studies	36% ± 14%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	37% ± 15%	Explore
endothelial cell of vascular tree	11 studies	52% ± 16%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	32% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	33% ± 9%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	23% ± 5%	Explore
T follicular helper cell	9 studies	54% ± 16%	Explore
mucosal invariant T cell	9 studies	28% ± 6%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	39% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	41% ± 14%	Explore
connective tissue cell	8 studies	36% ± 18%	Explore
innate lymphoid cell	7 studies	28% ± 7%	Explore
CD4-positive helper T cell	6 studies	34% ± 13%	Explore
hematopoietic stem cell	6 studies	34% ± 12%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	41% ± 11%	Explore
endothelial cell of lymphatic vessel	6 studies	24% ± 7%	Explore
hematopoietic precursor cell	5 studies	40% ± 13%	Explore
exhausted T cell	5 studies	57% ± 20%	Explore
leukocyte	5 studies	24% ± 5%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	51% ± 11%	Explore
glomerular endothelial cell	4 studies	45% ± 8%	Explore
adventitial cell	4 studies	27% ± 6%	Explore
basal cell	4 studies	28% ± 18%	Explore
T-helper 17 cell	4 studies	30% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	33% ± 11%	Explore
plasma cell	3 studies	27% ± 2%	Explore
intraepithelial lymphocyte	3 studies	51% ± 15%	Explore
Mueller cell	3 studies	27% ± 7%	Explore
granulocyte	3 studies	36% ± 13%	Explore
granulocyte monocyte progenitor cell	3 studies	41% ± 15%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	41% ± 22%	Explore
group 3 innate lymphoid cell	3 studies	33% ± 17%	Explore
goblet cell	3 studies	27% ± 10%	Explore
T-helper 1 cell	3 studies	39% ± 6%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	37% ± 7%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	25% ± 9%	Explore
double negative thymocyte	3 studies	47% ± 14%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	66% ± 16%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	13 studies	21% ± 3%	Explore
lung	7 studies	18% ± 3%	Explore
intestine	4 studies	23% ± 7%	Explore
breast	4 studies	27% ± 4%	Explore
kidney	3 studies	31% ± 11%	Explore
ovary	3 studies	23% ± 8%	Explore
thymus	3 studies	51% ± 24%	Explore
liver	3 studies	30% ± 5%	Explore
lymph node	3 studies	35% ± 2%	Explore
uterus	3 studies	23% ± 2%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	5100.50	653 / 653	98%	97.40	592 / 605
brain	98%	3808.00	2583 / 2642	99%	156.11	701 / 705
breast	100%	6086.17	459 / 459	80%	38.61	890 / 1118
lung	98%	2721.31	567 / 578	74%	24.60	856 / 1155
prostate	75%	1114.83	184 / 245	73%	27.07	365 / 502
stomach	87%	1615.05	314 / 359	53%	18.07	153 / 286
uterus	98%	3138.50	167 / 170	42%	26.45	194 / 459
bladder	100%	3369.57	21 / 21	36%	16.09	179 / 504
intestine	91%	1617.78	875 / 966	43%	13.77	226 / 527
ovary	100%	7532.44	180 / 180	33%	9.43	143 / 430
kidney	63%	759.98	56 / 89	70%	40.86	628 / 901
esophagus	92%	2199.18	1324 / 1445	40%	10.75	74 / 183
skin	69%	1459.15	1252 / 1809	56%	33.09	262 / 472
adipose	100%	5162.45	1203 / 1204	0%	0	0 / 0
heart	99%	4477.96	856 / 861	0%	0	0 / 0
blood vessel	95%	3000.74	1274 / 1335	0%	0	0 / 0
pancreas	19%	177.83	62 / 328	72%	29.96	129 / 178
spleen	87%	1150.62	210 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	83%	81.92	24 / 29
muscle	73%	856.67	586 / 803	0%	0	0 / 0
adrenal gland	25%	246.34	65 / 258	43%	12.61	99 / 230
tonsil	0%	0	0 / 0	62%	18.42	28 / 45
peripheral blood	60%	1519.80	562 / 929	0%	0	0 / 0
liver	0%	0	0 / 226	27%	9.77	111 / 406
eye	0%	0	0 / 0	21%	6.33	17 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1