Biological process

down regulation of amyloid precursor protein biosynthetic process, down-regulation of amyloid precursor protein biosynthetic process, downregulation of amyloid precursor protein biosynthetic process, negative regulation of APP biosynthesis, negative regulation of APP biosynthetic process, negative regulation of amyloid precursor protein anabolism, negative regulation of amyloid precursor protein biosynthesis, negative regulation of amyloid precursor protein formation, negative regulation of amyloid precursor protein synthesis

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta.