GYPC | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	37 studies	46% ± 14%	Explore
CD8-positive, alpha-beta T cell	35 studies	48% ± 19%	Explore
B cell	34 studies	36% ± 13%	Explore
fibroblast	33 studies	39% ± 16%	Explore
CD4-positive, alpha-beta T cell	31 studies	50% ± 17%	Explore
T cell	29 studies	43% ± 15%	Explore
macrophage	29 studies	35% ± 15%	Explore
endothelial cell of lymphatic vessel	28 studies	61% ± 26%	Explore
regulatory T cell	27 studies	49% ± 15%	Explore
endothelial cell	26 studies	34% ± 14%	Explore
pericyte	24 studies	31% ± 11%	Explore
mature NK T cell	20 studies	42% ± 15%	Explore
plasma cell	19 studies	43% ± 20%	Explore
smooth muscle cell	18 studies	30% ± 9%	Explore
gamma-delta T cell	18 studies	49% ± 15%	Explore
memory B cell	18 studies	35% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	48% ± 15%	Explore
naive B cell	17 studies	36% ± 12%	Explore
mucosal invariant T cell	16 studies	43% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	45% ± 13%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	43% ± 16%	Explore
erythrocyte	14 studies	72% ± 21%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	60% ± 16%	Explore
connective tissue cell	14 studies	38% ± 15%	Explore
capillary endothelial cell	13 studies	36% ± 9%	Explore
conventional dendritic cell	12 studies	26% ± 8%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	50% ± 19%	Explore
myofibroblast cell	12 studies	39% ± 17%	Explore
plasmablast	11 studies	43% ± 19%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	45% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	45% ± 20%	Explore
T follicular helper cell	9 studies	52% ± 13%	Explore
innate lymphoid cell	8 studies	44% ± 10%	Explore
mesothelial cell	8 studies	40% ± 17%	Explore
dendritic cell	8 studies	32% ± 14%	Explore
hematopoietic stem cell	8 studies	50% ± 20%	Explore
myeloid cell	8 studies	31% ± 7%	Explore
classical monocyte	7 studies	22% ± 6%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	46% ± 14%	Explore
leukocyte	7 studies	33% ± 11%	Explore
IgA plasma cell	7 studies	29% ± 12%	Explore
IgG plasma cell	7 studies	28% ± 11%	Explore
endothelial cell of vascular tree	7 studies	28% ± 9%	Explore
alveolar macrophage	6 studies	41% ± 13%	Explore
CD4-positive helper T cell	6 studies	34% ± 10%	Explore
erythroblast	6 studies	63% ± 22%	Explore
astrocyte	6 studies	59% ± 14%	Explore
microglial cell	6 studies	30% ± 10%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	47% ± 20%	Explore
mast cell	6 studies	25% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	33% ± 10%	Explore
exhausted T cell	5 studies	63% ± 14%	Explore
non-classical monocyte	5 studies	28% ± 12%	Explore
vein endothelial cell	5 studies	30% ± 10%	Explore
T-helper 17 cell	5 studies	54% ± 19%	Explore
double negative thymocyte	5 studies	57% ± 13%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	58% ± 20%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	40% ± 5%	Explore
hematopoietic precursor cell	4 studies	62% ± 17%	Explore
mononuclear phagocyte	4 studies	25% ± 9%	Explore
glomerular endothelial cell	4 studies	41% ± 8%	Explore
abnormal cell	4 studies	23% ± 4%	Explore
lymphocyte	4 studies	48% ± 19%	Explore
precursor B cell	4 studies	40% ± 11%	Explore
pro-B cell	4 studies	43% ± 8%	Explore
group 3 innate lymphoid cell	4 studies	67% ± 15%	Explore
monocyte	4 studies	28% ± 14%	Explore
adventitial cell	4 studies	36% ± 10%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	45% ± 19%	Explore
plasmacytoid dendritic cell	3 studies	18% ± 2%	Explore
platelet	3 studies	17% ± 1%	Explore
neural crest cell	3 studies	37% ± 4%	Explore
thymocyte	3 studies	38% ± 29%	Explore
immature B cell	3 studies	39% ± 9%	Explore
intraepithelial lymphocyte	3 studies	52% ± 10%	Explore
germinal center B cell	3 studies	57% ± 3%	Explore
basal cell	3 studies	28% ± 11%	Explore
myoepithelial cell	3 studies	44% ± 16%	Explore
IgM plasma cell	3 studies	35% ± 14%	Explore
melanocyte	3 studies	38% ± 23%	Explore
T-helper 1 cell	3 studies	52% ± 6%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	44% ± 13%	Explore
double-positive, alpha-beta thymocyte	3 studies	50% ± 13%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	18 studies	37% ± 9%	Explore
lung	12 studies	28% ± 9%	Explore
intestine	8 studies	28% ± 9%	Explore
liver	7 studies	37% ± 25%	Explore
bone marrow	6 studies	28% ± 9%	Explore
lymph node	5 studies	39% ± 17%	Explore
kidney	4 studies	33% ± 8%	Explore
uterus	4 studies	29% ± 8%	Explore
breast	3 studies	24% ± 2%	Explore
brain	3 studies	24% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	5624.95	459 / 459	89%	18.99	998 / 1118
kidney	97%	2242.54	86 / 89	91%	52.33	820 / 901
skin	88%	2455.37	1592 / 1809	99%	174.30	469 / 472
ovary	100%	4464.75	180 / 180	83%	18.53	359 / 430
lung	100%	5323.67	578 / 578	81%	15.56	935 / 1155
prostate	97%	2546.42	238 / 245	80%	13.24	401 / 502
adrenal gland	100%	3585.96	258 / 258	76%	18.04	174 / 230
thymus	97%	1832.80	634 / 653	74%	25.11	448 / 605
pancreas	63%	809.54	207 / 328	92%	26.07	163 / 178
uterus	99%	3268.76	169 / 170	52%	12.31	237 / 459
bladder	100%	3874.52	21 / 21	48%	9.62	241 / 504
intestine	94%	3401.62	910 / 966	48%	8.56	253 / 527
esophagus	90%	3431.42	1303 / 1445	44%	7.43	81 / 183
stomach	61%	1659.60	218 / 359	61%	13.10	175 / 286
adipose	100%	6757.47	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	263.00	80 / 80
lymph node	0%	0	0 / 0	100%	129.10	29 / 29
peripheral blood	100%	28363.67	929 / 929	0%	0	0 / 0
spleen	100%	4943.51	241 / 241	0%	0	0 / 0
blood vessel	100%	4572.89	1334 / 1335	0%	0	0 / 0
muscle	100%	3437.05	802 / 803	0%	0	0 / 0
heart	100%	3932.37	858 / 861	0%	0	0 / 0
brain	11%	121.84	293 / 2642	86%	23.43	609 / 705
tonsil	0%	0	0 / 0	84%	15.86	38 / 45
liver	17%	197.20	39 / 226	65%	14.21	263 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

IV. Literature review

[source]

Gene name	GYPC
Protein name	Glycophorin C Glycophorin Glycophorin-C (Glycoconnectin) (Glycophorin-D) (GPD) (Glycoprotein beta) (PAS-2') (Sialoglycoprotein D) (CD antigen CD236) Mutant glycophorin C
Synonyms	GE:GPC:GPD:GYPD GLPC GPC
Description	FUNCTION: This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells.
Accessions	A0A7T8ISH0 A8D444 A8UKF1 ENST00000259254.9 [P04921-1] A0A346RDK5 A0A346RDP8 A0A346RDJ1 P04921 A8UKE9 A8UKF0 ENST00000409836.3 [P04921-3] ENST00000356887.12 [P04921-2] A0A1M4M1Q5 A0A7T8EI91

GO_0030863	Cellular component	cortical cytoskeleton
GO_0016020	Cellular component	membrane
GO_0005886	Cellular component	plasma membrane
GO_0005515	Molecular function	protein binding

GYPC report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review