GPSM3 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	39 studies	48% ± 15%	Explore
B cell	37 studies	51% ± 18%	Explore
CD8-positive, alpha-beta T cell	36 studies	52% ± 18%	Explore
macrophage	32 studies	39% ± 13%	Explore
CD4-positive, alpha-beta T cell	32 studies	57% ± 17%	Explore
T cell	28 studies	48% ± 17%	Explore
conventional dendritic cell	28 studies	53% ± 18%	Explore
regulatory T cell	27 studies	52% ± 17%	Explore
classical monocyte	26 studies	59% ± 15%	Explore
non-classical monocyte	23 studies	68% ± 16%	Explore
mature NK T cell	20 studies	50% ± 15%	Explore
memory B cell	20 studies	60% ± 13%	Explore
naive B cell	20 studies	52% ± 14%	Explore
plasmacytoid dendritic cell	20 studies	54% ± 15%	Explore
monocyte	18 studies	54% ± 13%	Explore
gamma-delta T cell	18 studies	50% ± 17%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	58% ± 19%	Explore
dendritic cell	16 studies	53% ± 25%	Explore
mucosal invariant T cell	16 studies	50% ± 18%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	47% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	57% ± 13%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	64% ± 16%	Explore
mast cell	13 studies	27% ± 15%	Explore
neutrophil	13 studies	46% ± 19%	Explore
myeloid cell	13 studies	47% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	50% ± 22%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	54% ± 21%	Explore
plasma cell	11 studies	34% ± 10%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	59% ± 18%	Explore
innate lymphoid cell	9 studies	39% ± 11%	Explore
platelet	9 studies	40% ± 10%	Explore
T follicular helper cell	9 studies	57% ± 15%	Explore
plasmablast	8 studies	41% ± 17%	Explore
leukocyte	8 studies	35% ± 13%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	53% ± 24%	Explore
CD4-positive helper T cell	6 studies	41% ± 14%	Explore
hematopoietic precursor cell	6 studies	40% ± 22%	Explore
hematopoietic stem cell	6 studies	36% ± 10%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	65% ± 22%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	53% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	52% ± 16%	Explore
exhausted T cell	5 studies	67% ± 12%	Explore
mononuclear phagocyte	5 studies	48% ± 19%	Explore
precursor B cell	5 studies	48% ± 10%	Explore
T-helper 17 cell	5 studies	57% ± 17%	Explore
immature B cell	5 studies	65% ± 7%	Explore
alveolar macrophage	5 studies	28% ± 7%	Explore
double negative thymocyte	5 studies	66% ± 5%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	70% ± 26%	Explore
intermediate monocyte	5 studies	70% ± 19%	Explore
pro-B cell	4 studies	31% ± 8%	Explore
inflammatory macrophage	4 studies	34% ± 13%	Explore
group 3 innate lymphoid cell	4 studies	57% ± 9%	Explore
T-helper 1 cell	4 studies	70% ± 10%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	64% ± 16%	Explore
monocyte-derived dendritic cell	3 studies	50% ± 22%	Explore
megakaryocyte	3 studies	53% ± 2%	Explore
microglial cell	3 studies	38% ± 16%	Explore
intraepithelial lymphocyte	3 studies	42% ± 14%	Explore
germinal center B cell	3 studies	57% ± 2%	Explore
granulocyte	3 studies	42% ± 8%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	72% ± 14%	Explore
double-positive, alpha-beta thymocyte	3 studies	74% ± 9%	Explore
erythrocyte	3 studies	36% ± 16%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	19 studies	58% ± 16%	Explore
lung	11 studies	26% ± 9%	Explore
bone marrow	5 studies	32% ± 19%	Explore
lymph node	5 studies	45% ± 14%	Explore
liver	4 studies	32% ± 14%	Explore
intestine	3 studies	27% ± 4%	Explore
brain	3 studies	27% ± 9%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	4110.69	578 / 578	96%	56.60	1113 / 1155
breast	99%	1056.21	455 / 459	97%	46.46	1083 / 1118
intestine	92%	1626.37	890 / 966	92%	33.59	484 / 527
thymus	94%	823.04	612 / 653	88%	71.45	533 / 605
kidney	90%	892.17	80 / 89	90%	47.49	811 / 901
bladder	90%	1180.81	19 / 21	88%	39.66	442 / 504
stomach	88%	690.13	315 / 359	90%	31.84	258 / 286
prostate	96%	974.63	236 / 245	74%	16.19	370 / 502
uterus	76%	465.26	130 / 170	92%	34.03	421 / 459
skin	68%	381.67	1231 / 1809	100%	129.63	472 / 472
adrenal gland	94%	737.71	242 / 258	66%	17.81	152 / 230
esophagus	76%	514.95	1091 / 1445	74%	16.67	135 / 183
brain	44%	292.53	1172 / 2642	96%	44.39	675 / 705
liver	66%	433.96	149 / 226	65%	18.90	263 / 406
ovary	36%	210.07	65 / 180	92%	39.95	396 / 430
pancreas	18%	114.84	60 / 328	97%	63.13	172 / 178
eye	0%	0	0 / 0	100%	122.00	80 / 80
lymph node	0%	0	0 / 0	100%	371.93	29 / 29
peripheral blood	100%	39549.96	929 / 929	0%	0	0 / 0
spleen	100%	14633.47	241 / 241	0%	0	0 / 0
adipose	100%	1558.07	1202 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	96%	53.87	43 / 45
heart	69%	452.01	597 / 861	0%	0	0 / 0
blood vessel	66%	651.49	885 / 1335	0%	0	0 / 0
muscle	4%	17.05	31 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1