DECR1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	28 studies	24% ± 8%	Explore
natural killer cell	23 studies	24% ± 6%	Explore
fibroblast	23 studies	25% ± 9%	Explore
macrophage	20 studies	27% ± 12%	Explore
non-classical monocyte	19 studies	27% ± 11%	Explore
T cell	18 studies	23% ± 6%	Explore
CD4-positive, alpha-beta T cell	16 studies	23% ± 6%	Explore
CD8-positive, alpha-beta T cell	16 studies	25% ± 7%	Explore
conventional dendritic cell	15 studies	33% ± 16%	Explore
B cell	15 studies	21% ± 6%	Explore
regulatory T cell	14 studies	24% ± 8%	Explore
epithelial cell	13 studies	32% ± 19%	Explore
astrocyte	13 studies	32% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	24% ± 7%	Explore
classical monocyte	12 studies	26% ± 10%	Explore
oligodendrocyte precursor cell	11 studies	30% ± 15%	Explore
pericyte	10 studies	22% ± 4%	Explore
dendritic cell	10 studies	39% ± 22%	Explore
endothelial cell of lymphatic vessel	10 studies	20% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	21% ± 6%	Explore
progenitor cell	9 studies	22% ± 5%	Explore
connective tissue cell	9 studies	26% ± 5%	Explore
adipocyte	9 studies	51% ± 18%	Explore
alveolar macrophage	8 studies	31% ± 10%	Explore
basal cell	8 studies	34% ± 16%	Explore
mature NK T cell	8 studies	21% ± 3%	Explore
endothelial cell of artery	8 studies	19% ± 5%	Explore
smooth muscle cell	8 studies	19% ± 3%	Explore
myeloid cell	8 studies	25% ± 7%	Explore
monocyte	8 studies	26% ± 8%	Explore
gamma-delta T cell	8 studies	25% ± 15%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	21% ± 4%	Explore
epithelial cell of proximal tubule	7 studies	35% ± 6%	Explore
myofibroblast cell	7 studies	20% ± 3%	Explore
capillary endothelial cell	7 studies	19% ± 4%	Explore
enterocyte	7 studies	29% ± 8%	Explore
mucosal invariant T cell	7 studies	20% ± 4%	Explore
ciliated cell	7 studies	31% ± 15%	Explore
plasmacytoid dendritic cell	7 studies	23% ± 7%	Explore
GABAergic neuron	6 studies	31% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	22% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	20% ± 2%	Explore
kidney loop of Henle epithelial cell	6 studies	32% ± 12%	Explore
microglial cell	6 studies	21% ± 6%	Explore
abnormal cell	6 studies	28% ± 10%	Explore
cardiac muscle cell	6 studies	45% ± 8%	Explore
memory B cell	6 studies	19% ± 4%	Explore
plasma cell	5 studies	33% ± 11%	Explore
plasmablast	5 studies	45% ± 24%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	25% ± 7%	Explore
renal alpha-intercalated cell	5 studies	38% ± 9%	Explore
erythroblast	5 studies	31% ± 11%	Explore
lymphocyte	5 studies	25% ± 5%	Explore
type I pneumocyte	5 studies	23% ± 5%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	32% ± 14%	Explore
endothelial cell of vascular tree	5 studies	22% ± 2%	Explore
neuron	5 studies	32% ± 16%	Explore
hepatocyte	5 studies	53% ± 18%	Explore
goblet cell	5 studies	26% ± 9%	Explore
secretory cell	4 studies	30% ± 17%	Explore
exhausted T cell	4 studies	31% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	27% ± 9%	Explore
vein endothelial cell	4 studies	22% ± 5%	Explore
club cell	4 studies	27% ± 3%	Explore
mesothelial cell	4 studies	21% ± 6%	Explore
T follicular helper cell	4 studies	19% ± 2%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	35% ± 8%	Explore
mast cell	4 studies	24% ± 6%	Explore
glutamatergic neuron	4 studies	38% ± 16%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	26% ± 6%	Explore
enteroendocrine cell	4 studies	32% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	29% ± 16%	Explore
interneuron	4 studies	29% ± 15%	Explore
oligodendrocyte	4 studies	28% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	21% ± 5%	Explore
hematopoietic precursor cell	3 studies	31% ± 7%	Explore
respiratory goblet cell	3 studies	26% ± 15%	Explore
intestinal crypt stem cell	3 studies	28% ± 10%	Explore
brush cell	3 studies	29% ± 12%	Explore
precursor B cell	3 studies	19% ± 2%	Explore
type II pneumocyte	3 studies	23% ± 7%	Explore
muscle cell	3 studies	29% ± 12%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	47% ± 20%	Explore
transit amplifying cell	3 studies	18% ± 1%	Explore
hematopoietic stem cell	3 studies	20% ± 4%	Explore
naive B cell	3 studies	22% ± 5%	Explore
double negative thymocyte	3 studies	33% ± 15%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	13 studies	26% ± 11%	Explore
peripheral blood	11 studies	24% ± 6%	Explore
kidney	9 studies	23% ± 5%	Explore
intestine	9 studies	21% ± 8%	Explore
liver	7 studies	28% ± 12%	Explore
brain	7 studies	30% ± 11%	Explore
heart	6 studies	25% ± 7%	Explore
bone marrow	4 studies	19% ± 2%	Explore
adipose	4 studies	34% ± 19%	Explore
lymph node	3 studies	20% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	5629.70	89 / 89	100%	55.04	901 / 901
liver	100%	9712.63	226 / 226	100%	106.46	406 / 406
esophagus	100%	2504.06	1444 / 1445	100%	27.62	183 / 183
thymus	100%	2563.91	653 / 653	100%	38.99	604 / 605
prostate	100%	2331.91	245 / 245	100%	47.12	501 / 502
uterus	100%	1928.31	170 / 170	100%	41.48	458 / 459
adrenal gland	100%	7961.27	258 / 258	100%	55.46	229 / 230
skin	99%	2880.43	1798 / 1809	100%	40.54	472 / 472
breast	100%	3835.84	459 / 459	99%	49.03	1111 / 1118
lung	99%	2708.28	575 / 578	100%	33.50	1153 / 1155
bladder	100%	2310.14	21 / 21	99%	51.52	499 / 504
pancreas	99%	1683.75	326 / 328	99%	36.29	177 / 178
intestine	100%	3400.18	966 / 966	99%	43.14	520 / 527
stomach	100%	2317.87	359 / 359	99%	40.12	282 / 286
brain	98%	2079.30	2593 / 2642	100%	53.96	705 / 705
ovary	100%	2417.91	180 / 180	98%	22.99	420 / 430
adipose	100%	4151.55	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	47.16	29 / 29
muscle	100%	3889.44	803 / 803	0%	0	0 / 0
spleen	100%	3597.44	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	47.15	45 / 45
ureter	0%	0	0 / 0	100%	44.82	1 / 1
blood vessel	99%	1847.49	1324 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	99%	53.82	79 / 80
heart	98%	8959.43	848 / 861	0%	0	0 / 0
peripheral blood	97%	3325.60	901 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006635	Biological process	fatty acid beta-oxidation
GO_0120162	Biological process	positive regulation of cold-induced thermogenesis
GO_0005654	Cellular component	nucleoplasm
GO_1902494	Cellular component	catalytic complex
GO_0005829	Cellular component	cytosol
GO_0005759	Cellular component	mitochondrial matrix
GO_0005739	Cellular component	mitochondrion
GO_0005634	Cellular component	nucleus
GO_0070402	Molecular function	NADPH binding
GO_0008670	Molecular function	2,4-dienoyl-CoA reductase (NADPH) activity
GO_0042802	Molecular function	identical protein binding

IV. Literature review

[source]

Gene name	DECR1
Protein name	2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (EC 1.3.1.124) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) (Short chain dehydrogenase/reductase family 18C member 1) 2,4-dienoyl-CoA reductase 1 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] (EC 1.3.1.124)
Synonyms	SDR18C1 DECR
Description	FUNCTION: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. .
Accessions	ENST00000520227.1 E5RID6 ENST00000517761.5 E5RGS6 ENST00000519328.5 H0YAW3 ENST00000517314.5 E5RFV2 ENST00000522161.5 [Q16698-2] ENST00000521603.5 E5RJD2 E5RHR1 ENST00000220764.7 [Q16698-1] E5RJG7 Q16698 ENST00000517597.5 ENST00000519410.5 ENST00000520148.1 ENST00000518725.5

DECR1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review