CCDC12 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	33 studies	29% ± 9%	Explore
B cell	32 studies	27% ± 10%	Explore
CD8-positive, alpha-beta T cell	26 studies	25% ± 11%	Explore
CD4-positive, alpha-beta T cell	22 studies	22% ± 8%	Explore
T cell	20 studies	23% ± 5%	Explore
memory B cell	18 studies	26% ± 6%	Explore
regulatory T cell	18 studies	24% ± 4%	Explore
endothelial cell	17 studies	26% ± 9%	Explore
naive B cell	16 studies	26% ± 5%	Explore
non-classical monocyte	16 studies	34% ± 17%	Explore
gamma-delta T cell	16 studies	28% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	33% ± 11%	Explore
conventional dendritic cell	15 studies	28% ± 16%	Explore
epithelial cell	14 studies	33% ± 20%	Explore
mature NK T cell	13 studies	27% ± 7%	Explore
mast cell	12 studies	21% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	33% ± 9%	Explore
plasmacytoid dendritic cell	12 studies	35% ± 9%	Explore
fibroblast	12 studies	23% ± 7%	Explore
type I pneumocyte	11 studies	32% ± 9%	Explore
classical monocyte	11 studies	28% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	28% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	25% ± 7%	Explore
monocyte	10 studies	23% ± 6%	Explore
mucosal invariant T cell	10 studies	24% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	21% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	28% ± 13%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	22% ± 5%	Explore
capillary endothelial cell	8 studies	17% ± 1%	Explore
endothelial cell of artery	8 studies	18% ± 1%	Explore
basal cell	8 studies	33% ± 17%	Explore
ciliated cell	8 studies	34% ± 11%	Explore
plasma cell	7 studies	28% ± 11%	Explore
T follicular helper cell	7 studies	22% ± 3%	Explore
smooth muscle cell	6 studies	19% ± 4%	Explore
dendritic cell	6 studies	41% ± 23%	Explore
precursor B cell	6 studies	29% ± 5%	Explore
club cell	6 studies	26% ± 9%	Explore
endothelial cell of vascular tree	6 studies	19% ± 2%	Explore
goblet cell	6 studies	27% ± 8%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	25% ± 3%	Explore
leukocyte	5 studies	24% ± 7%	Explore
myofibroblast cell	5 studies	18% ± 4%	Explore
pericyte	5 studies	21% ± 6%	Explore
type II pneumocyte	5 studies	28% ± 8%	Explore
astrocyte	5 studies	23% ± 7%	Explore
innate lymphoid cell	5 studies	28% ± 4%	Explore
abnormal cell	5 studies	27% ± 5%	Explore
secretory cell	4 studies	29% ± 10%	Explore
pancreatic A cell	4 studies	32% ± 10%	Explore
hematopoietic precursor cell	4 studies	37% ± 18%	Explore
progenitor cell	4 studies	21% ± 5%	Explore
connective tissue cell	4 studies	24% ± 6%	Explore
lymphocyte	4 studies	26% ± 12%	Explore
pro-B cell	4 studies	23% ± 0%	Explore
myeloid cell	4 studies	26% ± 10%	Explore
enterocyte	4 studies	17% ± 1%	Explore
immature B cell	4 studies	29% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	31% ± 16%	Explore
adipocyte	4 studies	19% ± 4%	Explore
macrophage	4 studies	25% ± 6%	Explore
brush cell	4 studies	22% ± 8%	Explore
enteroendocrine cell	4 studies	30% ± 16%	Explore
transit amplifying cell	4 studies	22% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	25% ± 4%	Explore
exhausted T cell	3 studies	40% ± 14%	Explore
plasmablast	3 studies	50% ± 14%	Explore
kidney loop of Henle epithelial cell	3 studies	19% ± 1%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	18% ± 2%	Explore
neural crest cell	3 studies	18% ± 3%	Explore
retina horizontal cell	3 studies	23% ± 10%	Explore
intraepithelial lymphocyte	3 studies	27% ± 7%	Explore
endothelial cell of lymphatic vessel	3 studies	26% ± 8%	Explore
GABAergic neuron	3 studies	28% ± 8%	Explore
glutamatergic neuron	3 studies	38% ± 13%	Explore
intestinal crypt stem cell	3 studies	20% ± 5%	Explore
group 3 innate lymphoid cell	3 studies	29% ± 13%	Explore
T-helper 17 cell	3 studies	24% ± 6%	Explore
neuron	3 studies	34% ± 17%	Explore
oligodendrocyte	3 studies	18% ± 2%	Explore
double negative thymocyte	3 studies	38% ± 9%	Explore
microglial cell	3 studies	22% ± 4%	Explore
oligodendrocyte precursor cell	3 studies	19% ± 3%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	28% ± 11%	Explore
lung	9 studies	27% ± 8%	Explore
intestine	8 studies	21% ± 9%	Explore
brain	5 studies	26% ± 8%	Explore
pancreas	4 studies	28% ± 12%	Explore
liver	4 studies	31% ± 13%	Explore
kidney	3 studies	19% ± 2%	Explore
eye	3 studies	25% ± 5%	Explore
lymph node	3 studies	22% ± 5%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	2228.54	258 / 258	100%	27.00	230 / 230
esophagus	100%	1880.81	1445 / 1445	100%	13.35	183 / 183
ovary	100%	1632.18	180 / 180	100%	20.28	430 / 430
skin	100%	2314.73	1809 / 1809	100%	23.30	472 / 472
thymus	100%	1953.05	653 / 653	100%	39.64	605 / 605
uterus	100%	1910.99	170 / 170	100%	35.91	459 / 459
intestine	100%	1599.62	966 / 966	100%	26.40	526 / 527
brain	100%	1268.80	2636 / 2642	100%	27.15	705 / 705
pancreas	100%	950.88	327 / 328	100%	35.64	178 / 178
stomach	100%	1370.69	359 / 359	100%	20.55	285 / 286
prostate	100%	1747.97	245 / 245	100%	29.82	500 / 502
lung	100%	1707.67	578 / 578	100%	20.98	1150 / 1155
liver	100%	1033.16	226 / 226	100%	20.15	404 / 406
kidney	100%	1761.35	89 / 89	99%	19.85	894 / 901
bladder	100%	1703.24	21 / 21	99%	34.14	499 / 504
breast	100%	1768.97	459 / 459	99%	23.19	1106 / 1118
adipose	100%	1489.16	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	20.65	80 / 80
lymph node	0%	0	0 / 0	100%	67.63	29 / 29
spleen	100%	2004.14	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	27.82	45 / 45
ureter	0%	0	0 / 0	100%	82.83	1 / 1
blood vessel	100%	1404.24	1334 / 1335	0%	0	0 / 0
muscle	100%	1260.02	802 / 803	0%	0	0 / 0
heart	99%	1253.31	856 / 861	0%	0	0 / 0
peripheral blood	98%	1299.21	911 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0