ATOX1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	36 studies	46% ± 19%	Explore
endothelial cell	33 studies	41% ± 17%	Explore
fibroblast	28 studies	35% ± 14%	Explore
conventional dendritic cell	24 studies	36% ± 16%	Explore
smooth muscle cell	22 studies	28% ± 11%	Explore
non-classical monocyte	22 studies	37% ± 15%	Explore
classical monocyte	22 studies	37% ± 14%	Explore
pericyte	22 studies	35% ± 13%	Explore
natural killer cell	20 studies	22% ± 7%	Explore
dendritic cell	19 studies	44% ± 22%	Explore
epithelial cell	18 studies	41% ± 22%	Explore
monocyte	17 studies	41% ± 13%	Explore
endothelial cell of lymphatic vessel	15 studies	44% ± 16%	Explore
ciliated cell	15 studies	38% ± 17%	Explore
plasmacytoid dendritic cell	15 studies	30% ± 13%	Explore
connective tissue cell	14 studies	39% ± 10%	Explore
regulatory T cell	14 studies	25% ± 10%	Explore
plasma cell	13 studies	42% ± 12%	Explore
basal cell	12 studies	36% ± 18%	Explore
capillary endothelial cell	12 studies	37% ± 14%	Explore
endothelial cell of artery	12 studies	40% ± 18%	Explore
myeloid cell	12 studies	48% ± 22%	Explore
CD8-positive, alpha-beta T cell	11 studies	22% ± 6%	Explore
vein endothelial cell	11 studies	42% ± 17%	Explore
endothelial cell of vascular tree	11 studies	32% ± 11%	Explore
myofibroblast cell	10 studies	34% ± 10%	Explore
abnormal cell	10 studies	35% ± 18%	Explore
plasmablast	9 studies	39% ± 23%	Explore
progenitor cell	9 studies	39% ± 16%	Explore
secretory cell	8 studies	32% ± 19%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	20% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	23% ± 4%	Explore
CD4-positive, alpha-beta T cell	7 studies	28% ± 9%	Explore
epithelial cell of proximal tubule	7 studies	60% ± 15%	Explore
neuron	7 studies	38% ± 18%	Explore
enterocyte	7 studies	47% ± 18%	Explore
goblet cell	7 studies	31% ± 15%	Explore
mast cell	7 studies	34% ± 21%	Explore
alveolar macrophage	6 studies	38% ± 11%	Explore
club cell	6 studies	35% ± 5%	Explore
kidney loop of Henle epithelial cell	6 studies	37% ± 8%	Explore
renal alpha-intercalated cell	6 studies	54% ± 12%	Explore
T cell	6 studies	22% ± 8%	Explore
oligodendrocyte	6 studies	26% ± 10%	Explore
mesothelial cell	6 studies	45% ± 17%	Explore
B cell	6 studies	26% ± 8%	Explore
hematopoietic precursor cell	5 studies	33% ± 9%	Explore
respiratory goblet cell	5 studies	37% ± 11%	Explore
mononuclear phagocyte	5 studies	44% ± 17%	Explore
mature NK T cell	5 studies	19% ± 3%	Explore
enteroendocrine cell	5 studies	49% ± 17%	Explore
transit amplifying cell	5 studies	19% ± 4%	Explore
hematopoietic stem cell	5 studies	23% ± 11%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	27% ± 10%	Explore
ionocyte	4 studies	32% ± 11%	Explore
glomerular endothelial cell	4 studies	40% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	49% ± 7%	Explore
leukocyte	4 studies	35% ± 14%	Explore
retinal ganglion cell	4 studies	48% ± 27%	Explore
erythroblast	4 studies	34% ± 16%	Explore
innate lymphoid cell	4 studies	22% ± 6%	Explore
brush cell	4 studies	29% ± 13%	Explore
amacrine cell	4 studies	32% ± 15%	Explore
astrocyte	4 studies	26% ± 14%	Explore
microglial cell	4 studies	23% ± 8%	Explore
adventitial cell	4 studies	21% ± 3%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	26% ± 9%	Explore
intermediate monocyte	4 studies	52% ± 18%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	40% ± 11%	Explore
oligodendrocyte precursor cell	4 studies	25% ± 6%	Explore
gamma-delta T cell	4 studies	31% ± 21%	Explore
deuterosomal cell	3 studies	31% ± 9%	Explore
duct epithelial cell	3 studies	39% ± 15%	Explore
pancreatic A cell	3 studies	54% ± 8%	Explore
type B pancreatic cell	3 studies	38% ± 13%	Explore
podocyte	3 studies	66% ± 5%	Explore
neural crest cell	3 studies	26% ± 1%	Explore
IgA plasma cell	3 studies	27% ± 3%	Explore
IgG plasma cell	3 studies	25% ± 8%	Explore
memory B cell	3 studies	25% ± 8%	Explore
naive B cell	3 studies	22% ± 5%	Explore
extravillous trophoblast	3 studies	38% ± 6%	Explore
placental villous trophoblast	3 studies	35% ± 17%	Explore
common myeloid progenitor	3 studies	35% ± 8%	Explore
lymphocyte	3 studies	32% ± 3%	Explore
megakaryocyte	3 studies	31% ± 6%	Explore
neuroendocrine cell	3 studies	45% ± 19%	Explore
type I pneumocyte	3 studies	30% ± 14%	Explore
retinal pigment epithelial cell	3 studies	41% ± 31%	Explore
serous secreting cell	3 studies	48% ± 19%	Explore
Mueller cell	3 studies	32% ± 8%	Explore
T follicular helper cell	3 studies	17% ± 2%	Explore
germinal center B cell	3 studies	26% ± 0%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	25% ± 9%	Explore
exhausted T cell	3 studies	22% ± 6%	Explore
inflammatory macrophage	3 studies	44% ± 31%	Explore
luminal cell of prostate epithelium	3 studies	28% ± 7%	Explore
glutamatergic neuron	3 studies	30% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	16% ± 1%	Explore
granulocyte monocyte progenitor cell	3 studies	39% ± 1%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	45% ± 19%	Explore
glial cell	3 studies	37% ± 17%	Explore
keratinocyte	3 studies	18% ± 1%	Explore
neutrophil	3 studies	20% ± 2%	Explore
progenitor cell of mammary luminal epithelium	3 studies	24% ± 6%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	34% ± 15%	Explore
peripheral blood	12 studies	25% ± 6%	Explore
intestine	9 studies	33% ± 15%	Explore
kidney	9 studies	36% ± 11%	Explore
brain	7 studies	24% ± 7%	Explore
liver	6 studies	32% ± 18%	Explore
eye	5 studies	22% ± 8%	Explore
placenta	4 studies	36% ± 12%	Explore
bone marrow	4 studies	24% ± 10%	Explore
uterus	4 studies	35% ± 19%	Explore
breast	4 studies	27% ± 8%	Explore
pancreas	3 studies	43% ± 14%	Explore
adrenal gland	3 studies	20% ± 1%	Explore
skin	3 studies	21% ± 4%	Explore
thymus	3 studies	32% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1497.47	1445 / 1445	100%	17.51	183 / 183
kidney	100%	3008.20	89 / 89	100%	30.95	901 / 901
liver	100%	2202.43	226 / 226	100%	70.60	406 / 406
ovary	100%	1043.94	180 / 180	100%	27.55	430 / 430
skin	100%	2087.06	1809 / 1809	100%	61.76	472 / 472
stomach	100%	1052.92	359 / 359	100%	21.26	286 / 286
thymus	100%	2274.39	653 / 653	100%	32.54	605 / 605
brain	100%	1756.69	2641 / 2642	100%	28.81	705 / 705
prostate	100%	1821.83	245 / 245	100%	28.46	501 / 502
lung	100%	1485.75	577 / 578	100%	21.25	1154 / 1155
intestine	100%	1367.89	966 / 966	100%	21.98	525 / 527
uterus	100%	1274.84	170 / 170	100%	31.05	457 / 459
breast	100%	1781.43	459 / 459	99%	39.72	1111 / 1118
bladder	100%	1640.67	21 / 21	99%	25.96	500 / 504
adrenal gland	100%	2150.60	258 / 258	99%	26.77	228 / 230
pancreas	98%	580.98	323 / 328	99%	25.95	177 / 178
adipose	100%	1713.08	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	39.62	80 / 80
lymph node	0%	0	0 / 0	100%	106.61	29 / 29
spleen	100%	2199.22	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	29.45	45 / 45
ureter	0%	0	0 / 0	100%	17.24	1 / 1
blood vessel	100%	1733.67	1331 / 1335	0%	0	0 / 0
heart	99%	1154.45	854 / 861	0%	0	0 / 0
peripheral blood	95%	1319.95	886 / 929	0%	0	0 / 0
muscle	92%	543.31	738 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006878	Biological process	intracellular copper ion homeostasis
GO_0006979	Biological process	response to oxidative stress
GO_0006825	Biological process	copper ion transport
GO_0005829	Cellular component	cytosol
GO_0016530	Molecular function	metallochaperone activity
GO_1903136	Molecular function	cuprous ion binding
GO_0032767	Molecular function	copper-dependent protein binding
GO_0005507	Molecular function	copper ion binding
GO_0005515	Molecular function	protein binding
GO_0016531	Molecular function	copper chaperone activity

IV. Literature review

[source]

Gene name	ATOX1
Protein name	ATOX1 protein (Antioxidant 1 copper chaperone (EC 6.2.1.2)) Copper transport protein ATOX1 (Metal transport protein ATX1)
Synonyms	Atox1 HAH1
Description	FUNCTION: Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense. FUNCTION: Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense. . FUNCTION: Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense. . FUNCTION: Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense. .
Accessions	ENST00000524142.5 ENST00000522710.1 E5RGN3 ENST00000313115.11 ENST00000520382.5 E5RIM7 Q6IBA3 ENST00000522314.5 A0A2Z4T009 ENST00000521264.5 O00244

ATOX1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review