ANP32E | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	26 studies	27% ± 9%	Explore
T cell	21 studies	30% ± 13%	Explore
natural killer cell	21 studies	29% ± 12%	Explore
CD8-positive, alpha-beta T cell	19 studies	30% ± 14%	Explore
regulatory T cell	19 studies	25% ± 10%	Explore
CD4-positive, alpha-beta T cell	17 studies	34% ± 18%	Explore
gamma-delta T cell	15 studies	26% ± 11%	Explore
memory B cell	14 studies	24% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	23% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	23% ± 5%	Explore
naive B cell	11 studies	21% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	22% ± 4%	Explore
endothelial cell	10 studies	22% ± 8%	Explore
fibroblast	10 studies	21% ± 6%	Explore
smooth muscle cell	10 studies	19% ± 3%	Explore
mucosal invariant T cell	10 studies	28% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	9 studies	23% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	24% ± 6%	Explore
mature NK T cell	9 studies	22% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	25% ± 6%	Explore
plasmablast	8 studies	44% ± 22%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	26% ± 5%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	38% ± 13%	Explore
pericyte	7 studies	20% ± 3%	Explore
mast cell	6 studies	27% ± 5%	Explore
plasma cell	6 studies	38% ± 15%	Explore
conventional dendritic cell	6 studies	30% ± 9%	Explore
connective tissue cell	6 studies	21% ± 7%	Explore
abnormal cell	6 studies	24% ± 5%	Explore
retinal rod cell	6 studies	33% ± 16%	Explore
myeloid cell	6 studies	22% ± 7%	Explore
ciliated cell	6 studies	27% ± 10%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	31% ± 8%	Explore
innate lymphoid cell	6 studies	28% ± 6%	Explore
leukocyte	5 studies	28% ± 11%	Explore
hematopoietic precursor cell	5 studies	34% ± 9%	Explore
monocyte	5 studies	26% ± 13%	Explore
pro-B cell	5 studies	31% ± 11%	Explore
epithelial cell	5 studies	41% ± 17%	Explore
classical monocyte	4 studies	26% ± 9%	Explore
myofibroblast cell	4 studies	20% ± 4%	Explore
macrophage	4 studies	23% ± 3%	Explore
amacrine cell	4 studies	33% ± 16%	Explore
retina horizontal cell	4 studies	30% ± 9%	Explore
precursor B cell	4 studies	44% ± 24%	Explore
T follicular helper cell	4 studies	20% ± 3%	Explore
erythrocyte	4 studies	34% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	21% ± 5%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	24% ± 4%	Explore
exhausted T cell	3 studies	29% ± 7%	Explore
non-classical monocyte	3 studies	22% ± 6%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	28% ± 11%	Explore
neural crest cell	3 studies	28% ± 8%	Explore
retinal bipolar neuron	3 studies	42% ± 13%	Explore
erythroblast	3 studies	59% ± 27%	Explore
immature B cell	3 studies	19% ± 2%	Explore
astrocyte	3 studies	26% ± 9%	Explore
retinal cone cell	3 studies	62% ± 9%	Explore
retinal pigment epithelial cell	3 studies	27% ± 13%	Explore
Mueller cell	3 studies	30% ± 8%	Explore
rod bipolar cell	3 studies	28% ± 10%	Explore
germinal center B cell	3 studies	26% ± 11%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	36% ± 10%	Explore
basal cell	3 studies	35% ± 9%	Explore
granulocyte	3 studies	21% ± 4%	Explore
hematopoietic stem cell	3 studies	25% ± 7%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	48% ± 10%	Explore
group 3 innate lymphoid cell	3 studies	43% ± 12%	Explore
T-helper 1 cell	3 studies	34% ± 11%	Explore
T-helper 17 cell	3 studies	39% ± 21%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	26% ± 3%	Explore
double negative thymocyte	3 studies	33% ± 8%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	31% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	23% ± 6%	Explore
lung	7 studies	23% ± 9%	Explore
eye	6 studies	31% ± 15%	Explore
brain	4 studies	19% ± 2%	Explore
liver	4 studies	32% ± 26%	Explore
kidney	3 studies	19% ± 3%	Explore
intestine	3 studies	21% ± 7%	Explore
bone marrow	3 studies	22% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2229.56	1445 / 1445	100%	78.20	183 / 183
brain	100%	5006.57	2642 / 2642	100%	82.47	704 / 705
uterus	100%	2865.10	170 / 170	100%	117.48	458 / 459
lung	100%	2826.72	577 / 578	100%	102.17	1154 / 1155
ovary	100%	2603.49	180 / 180	100%	57.94	428 / 430
thymus	100%	2547.92	653 / 653	100%	86.94	602 / 605
bladder	100%	2516.24	21 / 21	98%	79.42	492 / 504
skin	100%	3218.96	1806 / 1809	98%	80.19	461 / 472
adrenal gland	100%	3228.46	258 / 258	97%	57.19	224 / 230
breast	100%	2216.09	459 / 459	97%	85.95	1086 / 1118
intestine	100%	2300.72	966 / 966	96%	56.33	504 / 527
liver	100%	1541.58	226 / 226	95%	41.89	386 / 406
kidney	100%	2134.72	89 / 89	94%	53.75	851 / 901
stomach	96%	1405.14	344 / 359	95%	54.66	273 / 286
pancreas	78%	693.30	257 / 328	99%	55.01	176 / 178
prostate	100%	2023.67	244 / 245	65%	16.40	327 / 502
lymph node	0%	0	0 / 0	100%	150.12	29 / 29
spleen	100%	2867.34	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	94.20	45 / 45
ureter	0%	0	0 / 0	100%	23.57	1 / 1
blood vessel	100%	3455.56	1334 / 1335	0%	0	0 / 0
muscle	100%	2501.67	802 / 803	0%	0	0 / 0
adipose	100%	2296.66	1202 / 1204	0%	0	0 / 0
heart	98%	1908.85	842 / 861	0%	0	0 / 0
peripheral blood	86%	4142.70	795 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	73%	25.68	58 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006325	Biological process	chromatin organization
GO_0006457	Biological process	protein folding
GO_0042981	Biological process	regulation of apoptotic process
GO_0000812	Cellular component	Swr1 complex
GO_0031410	Cellular component	cytoplasmic vesicle
GO_0005634	Cellular component	nucleus
GO_0044183	Molecular function	protein folding chaperone
GO_0005515	Molecular function	protein binding
GO_0140713	Molecular function	histone chaperone activity
GO_0042393	Molecular function	histone binding
GO_0019212	Molecular function	phosphatase inhibitor activity

IV. Literature review

[source]

Gene name	ANP32E
Protein name	Acidic (Leucine-rich) nuclear phosphoprotein 32 family, member E (Acidic nuclear phosphoprotein 32 family member E) Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP-like protein) (LANP-L) Acidic nuclear phosphoprotein 32 family member E Acidic leucine-rich nuclear phosphoprotein 32 family member
Synonyms	RP4-790G17.1-004 RP4-790G17.1-003
Description	FUNCTION: Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state . Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis. . FUNCTION: Multifunctional protein that is involved in the regulation of many processes. . FUNCTION: Multifunctional protein that is involved in the regulation of many processes. . FUNCTION: Multifunctional protein that is involved in the regulation of many processes. .
Accessions	H0YCE2 ENST00000369114.9 Q5TB25 Q5TB19 ENST00000534220.1 ENST00000616917.4 [Q9BTT0-3] ENST00000533654.5 E9PPH5 ENST00000532744.2 ENST00000534437.1 ENST00000369115.3 E9PLC4 ENST00000583931.6 [Q9BTT0-1] Q9BTT0 ENST00000436748.6 [Q9BTT0-2] ENST00000629042.2 E9PI45

ANP32E report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review