ACAP2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	37 studies	34% ± 13%	Explore
macrophage	35 studies	36% ± 18%	Explore
B cell	31 studies	29% ± 10%	Explore
natural killer cell	29 studies	27% ± 9%	Explore
classical monocyte	23 studies	42% ± 13%	Explore
CD8-positive, alpha-beta T cell	23 studies	24% ± 7%	Explore
pericyte	23 studies	22% ± 8%	Explore
regulatory T cell	22 studies	26% ± 7%	Explore
non-classical monocyte	21 studies	43% ± 12%	Explore
memory B cell	20 studies	27% ± 8%	Explore
astrocyte	20 studies	43% ± 19%	Explore
fibroblast	20 studies	28% ± 10%	Explore
T cell	19 studies	26% ± 7%	Explore
monocyte	19 studies	40% ± 15%	Explore
naive B cell	19 studies	29% ± 7%	Explore
CD4-positive, alpha-beta T cell	18 studies	24% ± 5%	Explore
mast cell	16 studies	25% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	27% ± 8%	Explore
conventional dendritic cell	15 studies	34% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	32% ± 8%	Explore
oligodendrocyte precursor cell	15 studies	35% ± 16%	Explore
microglial cell	15 studies	49% ± 16%	Explore
plasmacytoid dendritic cell	14 studies	30% ± 10%	Explore
endothelial cell of lymphatic vessel	13 studies	30% ± 11%	Explore
mature NK T cell	13 studies	26% ± 7%	Explore
glutamatergic neuron	13 studies	44% ± 25%	Explore
dendritic cell	13 studies	46% ± 18%	Explore
myeloid cell	13 studies	41% ± 14%	Explore
gamma-delta T cell	13 studies	29% ± 9%	Explore
ciliated cell	12 studies	26% ± 9%	Explore
epithelial cell	12 studies	34% ± 20%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	24% ± 5%	Explore
capillary endothelial cell	12 studies	23% ± 6%	Explore
smooth muscle cell	12 studies	23% ± 7%	Explore
oligodendrocyte	12 studies	33% ± 11%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	24% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	26% ± 8%	Explore
basal cell	11 studies	32% ± 17%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	24% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	26% ± 6%	Explore
mucosal invariant T cell	11 studies	28% ± 6%	Explore
GABAergic neuron	10 studies	46% ± 21%	Explore
vein endothelial cell	10 studies	26% ± 15%	Explore
neutrophil	9 studies	28% ± 10%	Explore
adipocyte	9 studies	28% ± 7%	Explore
endothelial cell of artery	8 studies	20% ± 2%	Explore
myofibroblast cell	8 studies	25% ± 10%	Explore
club cell	7 studies	23% ± 7%	Explore
leukocyte	7 studies	34% ± 15%	Explore
abnormal cell	7 studies	28% ± 11%	Explore
retinal cone cell	7 studies	31% ± 10%	Explore
alveolar macrophage	7 studies	38% ± 21%	Explore
endothelial cell of vascular tree	7 studies	29% ± 15%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	25% ± 7%	Explore
neuron	6 studies	44% ± 15%	Explore
interneuron	6 studies	52% ± 21%	Explore
hematopoietic stem cell	6 studies	24% ± 9%	Explore
amacrine cell	6 studies	35% ± 10%	Explore
retina horizontal cell	6 studies	54% ± 16%	Explore
type I pneumocyte	6 studies	24% ± 6%	Explore
type II pneumocyte	6 studies	24% ± 7%	Explore
connective tissue cell	6 studies	25% ± 6%	Explore
retinal ganglion cell	5 studies	30% ± 16%	Explore
lymphocyte	5 studies	37% ± 12%	Explore
precursor B cell	5 studies	31% ± 10%	Explore
mononuclear phagocyte	5 studies	34% ± 13%	Explore
Mueller cell	5 studies	29% ± 8%	Explore
retinal rod cell	5 studies	30% ± 7%	Explore
T follicular helper cell	5 studies	23% ± 5%	Explore
goblet cell	5 studies	31% ± 22%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	29% ± 4%	Explore
hematopoietic precursor cell	4 studies	39% ± 13%	Explore
plasma cell	4 studies	32% ± 9%	Explore
respiratory goblet cell	4 studies	24% ± 3%	Explore
secretory cell	4 studies	30% ± 6%	Explore
exhausted T cell	4 studies	28% ± 5%	Explore
plasmablast	4 studies	36% ± 17%	Explore
glial cell	4 studies	23% ± 5%	Explore
granule cell	4 studies	37% ± 11%	Explore
pro-B cell	4 studies	31% ± 8%	Explore
immature B cell	4 studies	37% ± 11%	Explore
cardiac muscle cell	4 studies	21% ± 3%	Explore
ON-bipolar cell	4 studies	24% ± 9%	Explore
intermediate monocyte	4 studies	49% ± 15%	Explore
innate lymphoid cell	4 studies	26% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	28% ± 4%	Explore
enteroendocrine cell	4 studies	22% ± 5%	Explore
squamous epithelial cell	3 studies	43% ± 21%	Explore
glomerular endothelial cell	3 studies	28% ± 2%	Explore
GABAergic interneuron	3 studies	37% ± 3%	Explore
progenitor cell	3 studies	22% ± 6%	Explore
mesothelial cell	3 studies	26% ± 8%	Explore
retinal bipolar neuron	3 studies	24% ± 2%	Explore
GABAergic amacrine cell	3 studies	36% ± 6%	Explore
OFF-bipolar cell	3 studies	25% ± 8%	Explore
glycinergic amacrine cell	3 studies	31% ± 2%	Explore
rod bipolar cell	3 studies	28% ± 9%	Explore
germinal center B cell	3 studies	32% ± 14%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	30% ± 2%	Explore
neural progenitor cell	3 studies	27% ± 7%	Explore
ependymal cell	3 studies	43% ± 17%	Explore
group 3 innate lymphoid cell	3 studies	30% ± 9%	Explore
brush cell	3 studies	24% ± 6%	Explore
double negative thymocyte	3 studies	36% ± 3%	Explore
mural cell	3 studies	44% ± 11%	Explore
mucus secreting cell	3 studies	27% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	19 studies	39% ± 20%	Explore
peripheral blood	17 studies	31% ± 9%	Explore
lung	13 studies	26% ± 9%	Explore
eye	6 studies	36% ± 15%	Explore
heart	5 studies	23% ± 5%	Explore
bone marrow	4 studies	28% ± 10%	Explore
kidney	4 studies	24% ± 4%	Explore
lymph node	4 studies	22% ± 4%	Explore
breast	4 studies	17% ± 0%	Explore
liver	4 studies	27% ± 12%	Explore
adipose	4 studies	35% ± 8%	Explore
intestine	3 studies	21% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3357.29	1445 / 1445	100%	40.26	183 / 183
lung	100%	3735.75	578 / 578	100%	28.88	1151 / 1155
ovary	100%	3565.19	180 / 180	100%	17.12	428 / 430
breast	100%	3479.87	459 / 459	99%	21.63	1105 / 1118
thymus	100%	3070.67	653 / 653	99%	17.87	597 / 605
brain	99%	2140.68	2604 / 2642	100%	17.71	702 / 705
uterus	100%	3370.91	170 / 170	97%	21.86	447 / 459
bladder	100%	3021.71	21 / 21	97%	16.89	490 / 504
stomach	100%	1851.63	358 / 359	97%	19.27	278 / 286
intestine	100%	3045.62	966 / 966	97%	15.62	509 / 527
prostate	100%	2284.95	244 / 245	96%	13.36	482 / 502
pancreas	96%	1203.60	316 / 328	98%	16.06	175 / 178
kidney	100%	1605.97	89 / 89	93%	14.06	840 / 901
skin	100%	4462.47	1808 / 1809	92%	18.16	436 / 472
adrenal gland	100%	1997.83	257 / 258	90%	9.06	207 / 230
liver	96%	1084.57	218 / 226	72%	5.91	293 / 406
adipose	100%	3936.52	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2876.20	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	20.28	29 / 29
spleen	100%	4283.22	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	44.69	45 / 45
ureter	0%	0	0 / 0	100%	5.70	1 / 1
peripheral blood	99%	5417.85	920 / 929	0%	0	0 / 0
muscle	94%	989.09	755 / 803	0%	0	0 / 0
heart	93%	1257.71	800 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	51%	4.00	41 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	ACAP2
Protein name	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein (Cnt-b) (Centaurin-beta) Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2)
Synonyms	CENTB2 KIAA0041
Description	FUNCTION: GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6). . FUNCTION: GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6). .; FUNCTION: GTPase-activating protein for the ADP ribosylation factor family. . FUNCTION: GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6). .; FUNCTION: GTPase-activating protein for the ADP ribosylation factor family. . FUNCTION: GTPase-activating protein for the ADP ribosylation factor family. . FUNCTION: GTPase-activating protein for the ADP ribosylation factor family. .
Accessions	A0A0U1RQT1 Q15057 ENST00000326793.11 ENST00000450200.2 ENST00000466876.2 F8WAU0 H7C3Q8 H7C3K3 ENST00000439758.3 A0A5F9ZHJ9 C9J8L1 ENST00000447662.1 ENST00000439666.1 ENST00000635383.1

GO_0030029	Biological process	actin filament-based process
GO_1990090	Biological process	cellular response to nerve growth factor stimulus
GO_0032456	Biological process	endocytic recycling
GO_0001726	Cellular component	ruffle
GO_0010008	Cellular component	endosome membrane
GO_0016020	Cellular component	membrane
GO_0046872	Molecular function	metal ion binding
GO_0005096	Molecular function	GTPase activator activity

ACAP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review