endoplasmic reticulum quality control compartment

I. Literature review

[source]
Nameendoplasmic reticulum quality control compartment
IDGO_0044322
collection_id

Cellular component

Exact synonym

ER quality control compartment, ERQC

Description

A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins.

Related synonym

ER-derived quality control compartment

External URL
Genes