ZC3H13 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	29 studies	29% ± 11%	Explore
fibroblast	25 studies	24% ± 7%	Explore
smooth muscle cell	20 studies	25% ± 5%	Explore
natural killer cell	19 studies	22% ± 4%	Explore
pericyte	19 studies	22% ± 6%	Explore
macrophage	17 studies	23% ± 7%	Explore
oligodendrocyte	14 studies	36% ± 15%	Explore
CD8-positive, alpha-beta T cell	13 studies	20% ± 5%	Explore
B cell	12 studies	19% ± 5%	Explore
oligodendrocyte precursor cell	12 studies	26% ± 10%	Explore
gamma-delta T cell	12 studies	22% ± 11%	Explore
mast cell	10 studies	22% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	20% ± 5%	Explore
CD4-positive, alpha-beta T cell	10 studies	19% ± 5%	Explore
epithelial cell	10 studies	33% ± 18%	Explore
glutamatergic neuron	10 studies	43% ± 26%	Explore
microglial cell	10 studies	25% ± 9%	Explore
astrocyte	10 studies	30% ± 15%	Explore
plasmacytoid dendritic cell	10 studies	22% ± 7%	Explore
endothelial cell of lymphatic vessel	9 studies	22% ± 3%	Explore
GABAergic neuron	9 studies	40% ± 23%	Explore
mature NK T cell	9 studies	21% ± 5%	Explore
myofibroblast cell	9 studies	27% ± 6%	Explore
connective tissue cell	9 studies	28% ± 7%	Explore
neuron	9 studies	36% ± 14%	Explore
mucosal invariant T cell	9 studies	18% ± 2%	Explore
ciliated cell	9 studies	26% ± 11%	Explore
regulatory T cell	9 studies	20% ± 4%	Explore
T cell	8 studies	22% ± 6%	Explore
type I pneumocyte	8 studies	21% ± 3%	Explore
non-classical monocyte	8 studies	23% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	21% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	19% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	21% ± 5%	Explore
basal cell	7 studies	28% ± 10%	Explore
leukocyte	6 studies	22% ± 2%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	23% ± 6%	Explore
capillary endothelial cell	6 studies	21% ± 1%	Explore
endothelial cell of artery	6 studies	19% ± 3%	Explore
interneuron	6 studies	46% ± 26%	Explore
myeloid cell	6 studies	26% ± 8%	Explore
amacrine cell	6 studies	32% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	24% ± 4%	Explore
classical monocyte	5 studies	23% ± 9%	Explore
naive B cell	5 studies	21% ± 3%	Explore
hepatocyte	5 studies	59% ± 23%	Explore
hematopoietic precursor cell	5 studies	26% ± 9%	Explore
abnormal cell	5 studies	28% ± 17%	Explore
vein endothelial cell	5 studies	19% ± 2%	Explore
retinal ganglion cell	5 studies	36% ± 17%	Explore
retina horizontal cell	5 studies	34% ± 11%	Explore
adipocyte	5 studies	23% ± 3%	Explore
lymphocyte	5 studies	25% ± 9%	Explore
Mueller cell	5 studies	23% ± 6%	Explore
endothelial cell of vascular tree	5 studies	22% ± 8%	Explore
innate lymphoid cell	5 studies	19% ± 4%	Explore
dendritic cell	5 studies	28% ± 11%	Explore
monocyte	5 studies	22% ± 4%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	22% ± 6%	Explore
conventional dendritic cell	4 studies	30% ± 15%	Explore
progenitor cell	4 studies	24% ± 4%	Explore
mesothelial cell	4 studies	21% ± 4%	Explore
retinal bipolar neuron	4 studies	27% ± 9%	Explore
granule cell	4 studies	22% ± 3%	Explore
type II pneumocyte	4 studies	23% ± 7%	Explore
retinal rod cell	4 studies	20% ± 4%	Explore
secretory cell	4 studies	21% ± 3%	Explore
enteroendocrine cell	4 studies	21% ± 9%	Explore
goblet cell	4 studies	27% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	21% ± 1%	Explore
neural crest cell	3 studies	30% ± 1%	Explore
GABAergic interneuron	3 studies	30% ± 5%	Explore
club cell	3 studies	25% ± 8%	Explore
precursor B cell	3 studies	28% ± 7%	Explore
pro-B cell	3 studies	23% ± 2%	Explore
retinal cone cell	3 studies	23% ± 6%	Explore
mononuclear phagocyte	3 studies	24% ± 10%	Explore
GABAergic amacrine cell	3 studies	23% ± 3%	Explore
OFF-bipolar cell	3 studies	20% ± 2%	Explore
ON-bipolar cell	3 studies	21% ± 3%	Explore
glycinergic amacrine cell	3 studies	21% ± 2%	Explore
rod bipolar cell	3 studies	29% ± 3%	Explore
respiratory goblet cell	3 studies	26% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	24% ± 6%	Explore
neural progenitor cell	3 studies	20% ± 0%	Explore
hematopoietic stem cell	3 studies	24% ± 3%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	34% ± 14%	Explore
group 3 innate lymphoid cell	3 studies	27% ± 10%	Explore
transit amplifying cell	3 studies	30% ± 19%	Explore
erythroblast	3 studies	34% ± 14%	Explore
double negative thymocyte	3 studies	27% ± 16%	Explore
memory B cell	3 studies	19% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	16 studies	36% ± 20%	Explore
lung	10 studies	21% ± 5%	Explore
liver	8 studies	32% ± 16%	Explore
peripheral blood	7 studies	23% ± 7%	Explore
eye	7 studies	24% ± 6%	Explore
intestine	6 studies	23% ± 10%	Explore
kidney	3 studies	19% ± 3%	Explore
uterus	3 studies	30% ± 14%	Explore
bone marrow	3 studies	24% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4526.57	1445 / 1445	100%	51.25	183 / 183
skin	100%	5804.20	1809 / 1809	99%	102.01	469 / 472
breast	100%	5031.76	459 / 459	99%	34.48	1107 / 1118
brain	100%	4823.48	2641 / 2642	99%	32.50	698 / 705
thymus	100%	5101.49	653 / 653	99%	29.39	597 / 605
ovary	100%	4909.43	180 / 180	99%	22.20	424 / 430
intestine	100%	5095.12	966 / 966	98%	29.27	518 / 527
prostate	100%	4106.99	245 / 245	98%	25.39	493 / 502
lung	100%	3934.93	576 / 578	98%	23.87	1135 / 1155
stomach	100%	3435.46	359 / 359	98%	34.56	280 / 286
bladder	100%	5047.62	21 / 21	97%	19.61	487 / 504
uterus	100%	6019.49	170 / 170	96%	20.73	441 / 459
pancreas	97%	2005.87	319 / 328	98%	20.69	174 / 178
kidney	100%	2712.62	89 / 89	94%	21.01	849 / 901
adrenal gland	100%	3406.63	257 / 258	91%	17.15	209 / 230
liver	100%	11290.50	226 / 226	77%	11.12	311 / 406
adipose	100%	4979.73	1204 / 1204	0%	0	0 / 0
blood vessel	100%	5725.62	1335 / 1335	0%	0	0 / 0
muscle	100%	3546.31	803 / 803	0%	0	0 / 0
spleen	100%	4041.13	241 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	21.59	28 / 29
eye	0%	0	0 / 0	96%	49.10	77 / 80
heart	95%	2422.01	820 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	91%	17.18	41 / 45
peripheral blood	67%	2235.48	627 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0008380	Biological process	RNA splicing
GO_2000036	Biological process	regulation of stem cell population maintenance
GO_0006397	Biological process	mRNA processing
GO_0016607	Cellular component	nuclear speck
GO_0005654	Cellular component	nucleoplasm
GO_0036396	Cellular component	RNA N6-methyladenosine methyltransferase complex
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	ZC3H13
Protein name	Zinc finger CCCH domain-containing protein 13 ZC3H13 protein Zinc finger CCCH-type containing 13 Alternative protein ZC3H13
Synonyms	KIAA0853
Description	FUNCTION: Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing . Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs at the 3'-UTR (By similarity). Controls embryonic stem cells (ESCs) pluripotency via its role in m6A methylation (By similarity). In the WMM complex, anchors component of the MACOM subcomplex in the nucleus (By similarity). Also required for bridging WTAP to the RNA-binding component RBM15 (RBM15 or RBM15B) (By similarity). .
Accessions	ENST00000242848.8 [Q5T200-1] ENST00000679008.1 Q32Q34 ENST00000464597.2 Q6PJ96 A0A7I2V4I5 Q5T200 ENST00000282007.7 [Q5T200-2] A0A087WX14 L8E857 A0PJJ2

ZC3H13 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review