RNA N6-methyladenosine methyltransferase complex

I. Literature review

[source]
NameRNA N6-methyladenosine methyltransferase complex
IDGO_0036396
collection_id

Cellular component

Exact synonym

Mum2, Ime4, and Slz1 complex, WMM complex

Description

A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B).

Related synonym

METTL3-METTL14-WTAP methyltransferase complex, MIS complex, m(6)A writer complex, m6A methyltransferase complex

External URL
Genes