Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 6 studies | 22% ± 4% | |
| epithelial cell | 5 studies | 29% ± 9% | |
| GABAergic neuron | 5 studies | 32% ± 12% | |
| astrocyte | 5 studies | 27% ± 7% | |
| oligodendrocyte | 5 studies | 24% ± 5% | |
| ciliated cell | 4 studies | 20% ± 4% | |
| glutamatergic neuron | 4 studies | 45% ± 16% | |
| interneuron | 4 studies | 32% ± 17% | |
| lymphocyte | 3 studies | 17% ± 1% | |
| oligodendrocyte precursor cell | 3 studies | 27% ± 6% | |
| dendritic cell | 3 studies | 21% ± 5% | |
| macrophage | 3 studies | 18% ± 2% | |
| transit amplifying cell | 3 studies | 23% ± 9% | |
| neuron | 3 studies | 25% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 3402.68 | 459 / 459 | 100% | 46.78 | 1118 / 1118 |
| esophagus | 100% | 2875.44 | 1445 / 1445 | 100% | 25.33 | 183 / 183 |
| stomach | 100% | 2627.92 | 359 / 359 | 100% | 20.64 | 286 / 286 |
| prostate | 100% | 2508.33 | 245 / 245 | 100% | 18.79 | 501 / 502 |
| ovary | 100% | 3527.68 | 180 / 180 | 100% | 18.01 | 429 / 430 |
| lung | 100% | 2603.38 | 576 / 578 | 100% | 22.19 | 1155 / 1155 |
| brain | 100% | 1899.99 | 2632 / 2642 | 100% | 18.49 | 705 / 705 |
| bladder | 100% | 3237.05 | 21 / 21 | 100% | 19.42 | 502 / 504 |
| uterus | 100% | 3825.16 | 170 / 170 | 100% | 20.02 | 457 / 459 |
| intestine | 100% | 3163.86 | 966 / 966 | 99% | 19.31 | 524 / 527 |
| thymus | 100% | 2779.53 | 653 / 653 | 99% | 17.61 | 600 / 605 |
| pancreas | 100% | 1928.67 | 327 / 328 | 99% | 17.15 | 177 / 178 |
| kidney | 100% | 1639.21 | 89 / 89 | 98% | 16.04 | 880 / 901 |
| liver | 100% | 1344.05 | 225 / 226 | 98% | 14.24 | 398 / 406 |
| skin | 100% | 4033.47 | 1809 / 1809 | 97% | 26.82 | 460 / 472 |
| adrenal gland | 100% | 2574.97 | 258 / 258 | 97% | 13.25 | 222 / 230 |
| adipose | 100% | 3308.38 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3399.43 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 17.19 | 29 / 29 |
| spleen | 100% | 2935.70 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 20.67 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 12.50 | 1 / 1 |
| muscle | 100% | 1765.41 | 800 / 803 | 0% | 0 | 0 / 0 |
| heart | 97% | 1605.92 | 834 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 95% | 20.09 | 76 / 80 |
| peripheral blood | 87% | 2201.30 | 807 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0008380 | Biological process | RNA splicing |
| GO_0006397 | Biological process | mRNA processing |
| GO_0016556 | Biological process | mRNA modification |
| GO_0016607 | Cellular component | nuclear speck |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0016604 | Cellular component | nuclear body |
| GO_0036396 | Cellular component | RNA N6-methyladenosine methyltransferase complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | VIRMA |
| Protein name | Protein virilizer homolog Vir like m6A methyltransferase associated |
| Synonyms | MSTP054 KIAA1429 |
| Description | FUNCTION: Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing . Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3'-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites . Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR near the stop codon correlating with alternative polyadenylation (APA) . . |
| Accessions | ENST00000297591.10 [Q69YN4-1] Q69YN4 ENST00000522263.5 ENST00000421249.2 [Q69YN4-4] H0YBN5 ENST00000517624.1 H0YC41 H0YB68 ENST00000523263.1 |