Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 6 studies | 22% ± 4% | |
epithelial cell | 5 studies | 29% ± 9% | |
GABAergic neuron | 5 studies | 32% ± 12% | |
astrocyte | 5 studies | 27% ± 7% | |
oligodendrocyte | 5 studies | 24% ± 5% | |
ciliated cell | 4 studies | 20% ± 4% | |
glutamatergic neuron | 4 studies | 45% ± 16% | |
interneuron | 4 studies | 32% ± 17% | |
lymphocyte | 3 studies | 17% ± 1% | |
oligodendrocyte precursor cell | 3 studies | 27% ± 6% | |
dendritic cell | 3 studies | 21% ± 5% | |
macrophage | 3 studies | 18% ± 2% | |
transit amplifying cell | 3 studies | 23% ± 9% | |
neuron | 3 studies | 25% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 3402.68 | 459 / 459 | 100% | 46.78 | 1118 / 1118 |
esophagus | 100% | 2875.44 | 1445 / 1445 | 100% | 25.33 | 183 / 183 |
stomach | 100% | 2627.92 | 359 / 359 | 100% | 20.64 | 286 / 286 |
prostate | 100% | 2508.33 | 245 / 245 | 100% | 18.79 | 501 / 502 |
ovary | 100% | 3527.68 | 180 / 180 | 100% | 18.01 | 429 / 430 |
lung | 100% | 2603.38 | 576 / 578 | 100% | 22.19 | 1155 / 1155 |
brain | 100% | 1899.99 | 2632 / 2642 | 100% | 18.49 | 705 / 705 |
bladder | 100% | 3237.05 | 21 / 21 | 100% | 19.42 | 502 / 504 |
uterus | 100% | 3825.16 | 170 / 170 | 100% | 20.02 | 457 / 459 |
intestine | 100% | 3163.86 | 966 / 966 | 99% | 19.31 | 524 / 527 |
thymus | 100% | 2779.53 | 653 / 653 | 99% | 17.61 | 600 / 605 |
pancreas | 100% | 1928.67 | 327 / 328 | 99% | 17.15 | 177 / 178 |
kidney | 100% | 1639.21 | 89 / 89 | 98% | 16.04 | 880 / 901 |
liver | 100% | 1344.05 | 225 / 226 | 98% | 14.24 | 398 / 406 |
skin | 100% | 4033.47 | 1809 / 1809 | 97% | 26.82 | 460 / 472 |
adrenal gland | 100% | 2574.97 | 258 / 258 | 97% | 13.25 | 222 / 230 |
adipose | 100% | 3308.38 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3399.43 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 17.19 | 29 / 29 |
spleen | 100% | 2935.70 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 20.67 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 12.50 | 1 / 1 |
muscle | 100% | 1765.41 | 800 / 803 | 0% | 0 | 0 / 0 |
heart | 97% | 1605.92 | 834 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 95% | 20.09 | 76 / 80 |
peripheral blood | 87% | 2201.30 | 807 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0008380 | Biological process | RNA splicing |
GO_0006397 | Biological process | mRNA processing |
GO_0016556 | Biological process | mRNA modification |
GO_0016607 | Cellular component | nuclear speck |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0016604 | Cellular component | nuclear body |
GO_0036396 | Cellular component | RNA N6-methyladenosine methyltransferase complex |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0003723 | Molecular function | RNA binding |
Gene name | VIRMA |
Protein name | Protein virilizer homolog Vir like m6A methyltransferase associated |
Synonyms | MSTP054 KIAA1429 |
Description | FUNCTION: Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing . Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3'-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites . Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR near the stop codon correlating with alternative polyadenylation (APA) . . |
Accessions | ENST00000297591.10 [Q69YN4-1] Q69YN4 ENST00000522263.5 ENST00000421249.2 [Q69YN4-4] H0YBN5 ENST00000517624.1 H0YC41 H0YB68 ENST00000523263.1 |