Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 8635.10 | 21 / 21 | 100% | 161.32 | 504 / 504 |
esophagus | 100% | 7653.24 | 1445 / 1445 | 100% | 116.11 | 183 / 183 |
intestine | 100% | 10014.45 | 966 / 966 | 100% | 177.12 | 527 / 527 |
uterus | 100% | 7022.98 | 170 / 170 | 100% | 141.22 | 459 / 459 |
skin | 100% | 4352.59 | 1805 / 1809 | 100% | 88.53 | 472 / 472 |
lung | 100% | 7708.29 | 577 / 578 | 100% | 117.68 | 1154 / 1155 |
stomach | 100% | 5841.92 | 358 / 359 | 100% | 163.93 | 286 / 286 |
thymus | 100% | 3586.21 | 651 / 653 | 100% | 91.56 | 604 / 605 |
breast | 100% | 5344.45 | 459 / 459 | 99% | 112.06 | 1110 / 1118 |
prostate | 100% | 6139.97 | 244 / 245 | 100% | 97.62 | 500 / 502 |
kidney | 98% | 3733.03 | 87 / 89 | 99% | 76.07 | 896 / 901 |
adrenal gland | 100% | 3114.57 | 257 / 258 | 92% | 46.31 | 212 / 230 |
ovary | 88% | 2449.53 | 158 / 180 | 100% | 85.89 | 430 / 430 |
liver | 75% | 1819.13 | 170 / 226 | 94% | 61.56 | 383 / 406 |
pancreas | 56% | 1115.09 | 185 / 328 | 99% | 214.08 | 177 / 178 |
adipose | 100% | 5779.92 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 233.43 | 29 / 29 |
peripheral blood | 100% | 33350.04 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 14374.19 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 108.77 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 78.51 | 1 / 1 |
blood vessel | 100% | 7884.91 | 1333 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 98% | 43.07 | 78 / 80 |
heart | 96% | 2866.06 | 827 / 861 | 0% | 0 | 0 / 0 |
brain | 17% | 273.98 | 442 / 2642 | 77% | 33.18 | 541 / 705 |
muscle | 22% | 345.91 | 175 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030838 | Biological process | positive regulation of actin filament polymerization |
GO_0008154 | Biological process | actin polymerization or depolymerization |
GO_0030036 | Biological process | actin cytoskeleton organization |
GO_0001843 | Biological process | neural tube closure |
GO_0007411 | Biological process | axon guidance |
GO_0051289 | Biological process | protein homotetramerization |
GO_0005886 | Cellular component | plasma membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005925 | Cellular component | focal adhesion |
GO_0031527 | Cellular component | filopodium membrane |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0031258 | Cellular component | lamellipodium membrane |
GO_0005829 | Cellular component | cytosol |
GO_0005923 | Cellular component | bicellular tight junction |
GO_0045296 | Molecular function | cadherin binding |
GO_0005522 | Molecular function | profilin binding |
GO_0005515 | Molecular function | protein binding |
GO_0003779 | Molecular function | actin binding |
GO_0017124 | Molecular function | SH3 domain binding |
Gene name | VASP |
Protein name | Vasodilator-stimulated phosphoprotein isoform 3 Vasodilator-stimulated phosphoprotein isoform 1 Vasodilator-stimulated phosphoprotein isoform 2 Vasodilator-stimulated phosphoprotein (VASP) Vasodilator stimulated phosphoprotein Vasodilator-stimulated phosphoprotein isoform 4 Vasodilator-stimulated phosphoprotein isoform 5 |
Synonyms | |
Description | FUNCTION: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation. . |
Accessions | A0A994J508 K7ENR7 A0A0S2Z4I9 P50552 ENST00000586014.5 ENST00000589627.1 ENST00000245932.11 A0A0S2Z4H6 K7ENL7 A0A0S2Z4I7 K7EQD0 ENST00000592139.1 K7EIG8 ENST00000588482.5 ENST00000705986.1 A0A024R0V4 K7EM16 A0A994J7X3 ENST00000590603.1 A0A0S2Z4N8 ENST00000705987.1 |