SYPL1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
B cell	35 studies	37% ± 11%	Explore
endothelial cell	34 studies	35% ± 13%	Explore
fibroblast	30 studies	28% ± 10%	Explore
pericyte	23 studies	34% ± 9%	Explore
smooth muscle cell	22 studies	31% ± 9%	Explore
endothelial cell of lymphatic vessel	20 studies	45% ± 15%	Explore
memory B cell	20 studies	40% ± 10%	Explore
naive B cell	20 studies	34% ± 10%	Explore
basal cell	20 studies	40% ± 19%	Explore
CD4-positive, alpha-beta T cell	18 studies	20% ± 4%	Explore
epithelial cell	17 studies	37% ± 19%	Explore
ciliated cell	15 studies	39% ± 15%	Explore
capillary endothelial cell	13 studies	32% ± 7%	Explore
myofibroblast cell	13 studies	25% ± 7%	Explore
mast cell	12 studies	25% ± 6%	Explore
vein endothelial cell	12 studies	30% ± 7%	Explore
regulatory T cell	12 studies	20% ± 4%	Explore
endothelial cell of vascular tree	12 studies	33% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	11 studies	21% ± 4%	Explore
endothelial cell of artery	11 studies	30% ± 7%	Explore
secretory cell	10 studies	33% ± 13%	Explore
connective tissue cell	10 studies	28% ± 8%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	20% ± 4%	Explore
macrophage	9 studies	20% ± 5%	Explore
type I pneumocyte	8 studies	25% ± 9%	Explore
T cell	8 studies	24% ± 4%	Explore
oligodendrocyte	8 studies	28% ± 12%	Explore
hematopoietic stem cell	7 studies	44% ± 14%	Explore
type II pneumocyte	7 studies	25% ± 12%	Explore
T follicular helper cell	7 studies	22% ± 4%	Explore
plasmacytoid dendritic cell	7 studies	22% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	21% ± 3%	Explore
epithelial cell of proximal tubule	6 studies	26% ± 6%	Explore
kidney loop of Henle epithelial cell	6 studies	26% ± 12%	Explore
renal alpha-intercalated cell	6 studies	49% ± 13%	Explore
abnormal cell	6 studies	39% ± 10%	Explore
precursor B cell	6 studies	34% ± 11%	Explore
astrocyte	6 studies	26% ± 11%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	21% ± 6%	Explore
classical monocyte	5 studies	23% ± 7%	Explore
conventional dendritic cell	5 studies	28% ± 10%	Explore
CD8-positive, alpha-beta T cell	5 studies	20% ± 6%	Explore
mesothelial cell	5 studies	36% ± 18%	Explore
club cell	5 studies	32% ± 13%	Explore
hematopoietic precursor cell	4 studies	47% ± 21%	Explore
non-classical monocyte	4 studies	29% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	20% ± 2%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	28% ± 9%	Explore
pro-B cell	4 studies	35% ± 9%	Explore
immature B cell	4 studies	38% ± 5%	Explore
germinal center B cell	4 studies	44% ± 18%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	20% ± 3%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	23% ± 6%	Explore
innate lymphoid cell	4 studies	22% ± 4%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	33% ± 5%	Explore
goblet cell	4 studies	30% ± 11%	Explore
glial cell	4 studies	29% ± 14%	Explore
duct epithelial cell	3 studies	25% ± 3%	Explore
hillock cell	3 studies	27% ± 8%	Explore
respiratory goblet cell	3 studies	27% ± 11%	Explore
glomerular endothelial cell	3 studies	33% ± 5%	Explore
progenitor cell	3 studies	21% ± 2%	Explore
extravillous trophoblast	3 studies	21% ± 5%	Explore
myeloid cell	3 studies	29% ± 10%	Explore
monocyte	3 studies	20% ± 4%	Explore
serous secreting cell	3 studies	40% ± 9%	Explore
Mueller cell	3 studies	28% ± 5%	Explore
gamma-delta T cell	3 studies	33% ± 19%	Explore
myoepithelial cell	3 studies	33% ± 7%	Explore
granulocyte	3 studies	24% ± 6%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	42% ± 31%	Explore
enteroendocrine cell	3 studies	25% ± 5%	Explore
intestinal crypt stem cell	3 studies	27% ± 4%	Explore
leukocyte	3 studies	22% ± 2%	Explore
group 3 innate lymphoid cell	3 studies	32% ± 10%	Explore
transit amplifying cell	3 studies	18% ± 2%	Explore
keratinocyte	3 studies	31% ± 3%	Explore
progenitor cell of mammary luminal epithelium	3 studies	20% ± 4%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	15 studies	29% ± 14%	Explore
peripheral blood	10 studies	22% ± 9%	Explore
kidney	8 studies	22% ± 6%	Explore
brain	6 studies	21% ± 3%	Explore
uterus	5 studies	27% ± 15%	Explore
intestine	5 studies	25% ± 10%	Explore
placenta	4 studies	29% ± 6%	Explore
prostate	4 studies	27% ± 11%	Explore
lymph node	4 studies	36% ± 7%	Explore
breast	4 studies	25% ± 1%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	8907.69	1445 / 1445	100%	243.44	183 / 183
ovary	100%	5410.36	180 / 180	100%	140.30	430 / 430
bladder	100%	8414.29	21 / 21	100%	219.45	503 / 504
uterus	100%	8282.28	170 / 170	100%	196.45	458 / 459
stomach	100%	5635.67	359 / 359	100%	167.08	285 / 286
lung	100%	5671.13	576 / 578	100%	192.32	1153 / 1155
intestine	100%	7236.93	966 / 966	99%	190.91	524 / 527
prostate	100%	6010.89	245 / 245	99%	180.91	499 / 502
thymus	100%	7253.40	653 / 653	99%	167.53	601 / 605
breast	100%	7522.40	459 / 459	99%	196.84	1110 / 1118
kidney	100%	5443.73	89 / 89	99%	177.23	893 / 901
pancreas	98%	3035.67	323 / 328	99%	170.00	176 / 178
skin	100%	7267.28	1809 / 1809	97%	148.74	458 / 472
liver	99%	2616.03	224 / 226	98%	92.29	396 / 406
adrenal gland	100%	5965.60	258 / 258	93%	75.76	213 / 230
brain	87%	2922.84	2290 / 2642	100%	117.53	702 / 705
adipose	100%	7271.10	1204 / 1204	0%	0	0 / 0
blood vessel	100%	6749.93	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	155.02	29 / 29
muscle	100%	6825.00	803 / 803	0%	0	0 / 0
spleen	100%	4673.42	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	232.38	45 / 45
ureter	0%	0	0 / 0	100%	93.43	1 / 1
heart	99%	4165.08	853 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	91%	69.51	73 / 80
peripheral blood	60%	1571.74	562 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0